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Entry version 131 (12 Aug 2020)
Sequence version 2 (27 Jul 2011)
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Protein

ATPase MORC2B

Gene

Morc2b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for chromosomal synapsis and meiotic recombination in males and females.1 Publication

Miscellaneous

Retrotransposed homolog of Morc2a.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi39MagnesiumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei39ATPBy similarity1
Binding sitei427ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi87 – 89ATPBy similarity3
Nucleotide bindingi99 – 105ATPBy similarity7
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri490 – 544CW-typePROSITE-ProRule annotationAdd BLAST55

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATPase MORC2BCurated (EC:3.6.1.-By similarity)
Alternative name(s):
MORC family CW-type zinc finger protein 2BCurated
TCE6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Morc2bImported
Synonyms:Tce6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3045293, Morc2b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Knockouts are viable and appear to be grossly normal. Mutant males and females show meiotic arrest and sterility. Males have significantly smaller testes than control males. Their testes weigh approximately 70% less than control testes. Their spermatocytes and oocytes exhibit failures in chromosomal synapsis, blockades in meiotic recombination, and increased apoptosis (PubMed:29329290). The ovaries of adult female mutant mice are much smaller than those from heterozygous littermates and are devoid of oocytes (PubMed:29329290).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002482442 – 1022ATPase MORC2BAdd BLAST1021

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei615PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki649Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei690PhosphoserineBy similarity1
Modified residuei724PhosphoserineBy similarity1
Modified residuei733PhosphoserineBy similarity1
Modified residuei737PhosphoserineBy similarity1
Cross-linki758Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei768PhosphoserineBy similarity1
Modified residuei770PhosphoserineBy similarity1
Modified residuei827PhosphothreonineBy similarity1
Modified residuei846PhosphoserineBy similarity1
Modified residuei851PhosphoserineBy similarity1
Cross-linki922Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8C5W4

PRoteomics IDEntifications database

More...
PRIDEi
Q8C5W4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8C5W4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8C5W4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Protein is abundant in testes but not detected in other adult tissues examined (at protein level). Detected in germ cells with a distinct developmental-specific expression pattern but not in somatic cells such as Sertoli cells.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In juvenile testes, expression is absent prior to postnatal day 12, is detected at a low level at day 12, and increased significantly at day 14 and beyond. In adul testes, expressed in meiotic spermatocytes, abundant in post-meiotic haploid round spermatids, and absent from elongated spermatids.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000048602, Expressed in spermatocyte and 37 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8C5W4, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Morc2a.

1 Publication

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8C5W4, 1 interactor

STRING: functional protein association networks

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STRINGi
10090.ENSMUSP00000123354

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8C5W4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8C5W4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili285 – 362Sequence analysisAdd BLAST78
Coiled coili555 – 583Sequence analysisAdd BLAST29
Coiled coili962 – 1001Sequence analysisAdd BLAST40

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri490 – 544CW-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1845, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153998

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011516_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8C5W4

KEGG Orthology (KO)

More...
KOi
K24135

Identification of Orthologs from Complete Genome Data

More...
OMAi
PRDCWVE

Database of Orthologous Groups

More...
OrthoDBi
193855at2759

TreeFam database of animal gene trees

More...
TreeFami
TF329118

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55874, SSF55874, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51050, ZF_CW, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 11 Publication (identifier: Q8C5W4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAFTNYSTLN RAQLTFDYLH TNSTTHAFLF GALAELIDNA RDADATRIDI
60 70 80 90 100
YAEKREDLQG GFMLCFLDNG VGMDPNDVIN VIQFGKSAKR TPESTQIGRY
110 120 130 140 150
GNGLKSGSMR IGKDFILFTK KENTMSCLFL SRTFHEEEGI DEVIVPLPTW
160 170 180 190 200
NSQTREPVTD NMEKFAIETE LIYKYSPFHT EEEVMTQFTK ISGTSGTLVV
210 220 230 240 250
IFNLKLTDNG EPELDVTSNP KDIRMAEISQ EGVKPERHSF CAYAAVLYID
260 270 280 290 300
PRMRIFIHGH KVQTKKLCCC LYKPRKYTFT SHRFKTRAEQ EVKKADQVAQ
310 320 330 340 350
LAEEKAREAE SKARTLEIHM GGDITRDSRV MLRQVQNTAI TLRREADVKK
360 370 380 390 400
RIRDAKQQAL KEPKELTFVF GVNIEHRDHD GMFIYNCSRL IKMYEKVGPQ
410 420 430 440 450
LEKGMVCGGV VGVIDVPYLV LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY
460 470 480 490 500
WKDIEIAQHG IIKFWDEFGY LSANWNRPPS DELHFKRKRA MQVPTTIQCD
510 520 530 540 550
LCLKWRTLPF QLSAVEEGYP INWVCSMNPD PEQDQCEAFE LKQKIPLGIL
560 570 580 590 600
KKAPKTQEER QKQLTEKIQQ EQRKLKALKK IKPIHSQSDL KKLPLEVTSR
610 620 630 640 650
PFSKYPAHIF QGPQSSFHVV KTNARRRPQS RHAPFRQLQR SSIICTNPKP
660 670 680 690 700
PFLVDKTEAV LLQPPETPQK SVSLLVKTIP QPPPLVQSLS PSVVPKSNNP
710 720 730 740 750
WKVETPQIMN TPVAEMPYVP VNPSLVICDH KRSPEVSDEI EDEDRRKRMC
760 770 780 790 800
KRGRFTVKKE KIQASELSDS SGEENPVDLK TAQKDKGLYV EVRMMGECYK
810 820 830 840 850
GHVTAVEVGD NVVWWKVKFE DMPKDSTPRD CWVEKGSENV WLVKPSPEYQ
860 870 880 890 900
STDEQQEDRK GEEDTVVQQA LALQQTSTSE CFCTEPDTTA STANHKTIDL
910 920 930 940 950
LVQILWNCLH YFMPLSFPIS KKELGAMNSE ELLSLPLKEC FKQYEVGLQN
960 970 980 990 1000
LCRSYQRCAD SQAKVSEESL RISQKKLQET EEKLQKLRTN IQTLLQMAQQ
1010 1020
GINIRADDEL DAYIEDLVSS DD
Length:1,022
Mass (Da):117,186
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6AFABF5964A1B8A0
GO
Isoform 21 Publication (identifier: Q8C5W4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     812-835: Missing.

Show »
Length:998
Mass (Da):114,194
Checksum:i4F8B671BC165BC04
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti521I → V in AAO17388 (PubMed:15112104).Curated1
Sequence conflicti674L → P in AAO17388 (PubMed:15112104).Curated1
Sequence conflicti731K → E in BAC36567 (PubMed:16141072).Curated1
Sequence conflicti943Q → R in BAC36567 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_052135812 – 835Missing in isoform 2. 1 PublicationAdd BLAST24

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK077016 mRNA Translation: BAC36567.1
AF528164 Genomic DNA Translation: AAO17388.1
CT033756 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37561.1 [Q8C5W4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_808387.2, NM_177719.4 [Q8C5W4-1]
XP_006524320.1, XM_006524257.2 [Q8C5W4-1]
XP_006524321.1, XM_006524258.2 [Q8C5W4-1]
XP_006524322.1, XM_006524259.2
XP_011244746.1, XM_011246444.1 [Q8C5W4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000053896; ENSMUSP00000056879; ENSMUSG00000048602 [Q8C5W4-1]
ENSMUST00000131954; ENSMUSP00000123354; ENSMUSG00000048602 [Q8C5W4-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
240069

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:240069

UCSC genome browser

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UCSCi
uc008byc.2, mouse [Q8C5W4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK077016 mRNA Translation: BAC36567.1
AF528164 Genomic DNA Translation: AAO17388.1
CT033756 Genomic DNA No translation available.
CCDSiCCDS37561.1 [Q8C5W4-1]
RefSeqiNP_808387.2, NM_177719.4 [Q8C5W4-1]
XP_006524320.1, XM_006524257.2 [Q8C5W4-1]
XP_006524321.1, XM_006524258.2 [Q8C5W4-1]
XP_006524322.1, XM_006524259.2
XP_011244746.1, XM_011246444.1 [Q8C5W4-1]

3D structure databases

SMRiQ8C5W4
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8C5W4, 1 interactor
STRINGi10090.ENSMUSP00000123354

PTM databases

iPTMnetiQ8C5W4
PhosphoSitePlusiQ8C5W4

Proteomic databases

PaxDbiQ8C5W4
PRIDEiQ8C5W4

Genome annotation databases

EnsembliENSMUST00000053896; ENSMUSP00000056879; ENSMUSG00000048602 [Q8C5W4-1]
ENSMUST00000131954; ENSMUSP00000123354; ENSMUSG00000048602 [Q8C5W4-1]
GeneIDi240069
KEGGimmu:240069
UCSCiuc008byc.2, mouse [Q8C5W4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
240069
MGIiMGI:3045293, Morc2b

Phylogenomic databases

eggNOGiKOG1845, Eukaryota
GeneTreeiENSGT00940000153998
HOGENOMiCLU_011516_0_0_1
InParanoidiQ8C5W4
KOiK24135
OMAiPRDCWVE
OrthoDBi193855at2759
TreeFamiTF329118

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
240069, 0 hits in 18 CRISPR screens

Protein Ontology

More...
PROi
PR:Q8C5W4
RNActiQ8C5W4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000048602, Expressed in spermatocyte and 37 other tissues
GenevisibleiQ8C5W4, MM

Family and domain databases

Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR036890, HATPase_C_sf
IPR041006, Morc_S5
IPR011124, Znf_CW
PfamiView protein in Pfam
PF17942, Morc6_S5, 1 hit
PF07496, zf-CW, 1 hit
SUPFAMiSSF55874, SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS51050, ZF_CW, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOR2B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C5W4
Secondary accession number(s): B8JK02, Q8CG24
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: July 27, 2011
Last modified: August 12, 2020
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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