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Protein

RNA-binding protein 34

Gene

Rbm34

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 34
Alternative name(s):
RNA-binding motif protein 34
Gene namesi
Name:Rbm34
Synonyms:D8Ertd233e
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1098653 Rbm34

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000817911 – 375RNA-binding protein 34Add BLAST375

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei153N6-acetyllysineCombined sources1
Cross-linki246Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei292PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ8C5L7
MaxQBiQ8C5L7
PaxDbiQ8C5L7
PeptideAtlasiQ8C5L7
PRIDEiQ8C5L7

PTM databases

iPTMnetiQ8C5L7
PhosphoSitePlusiQ8C5L7

Expressioni

Gene expression databases

CleanExiMM_RBM34

Interactioni

Protein-protein interaction databases

BioGridi206450, 2 interactors
STRINGi10090.ENSMUSP00000048450

Structurei

3D structure databases

ProteinModelPortaliQ8C5L7
SMRiQ8C5L7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 284RRM 1PROSITE-ProRule annotationAdd BLAST96
Domaini291 – 368RRM 2PROSITE-ProRule annotationAdd BLAST78

Sequence similaritiesi

Belongs to the RRM RBM34 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0118 Eukaryota
COG0724 LUCA
HOVERGENiHBG052167
InParanoidiQ8C5L7
KOiK14837

Family and domain databases

CDDicd12394 RRM1_RBM34, 1 hit
cd12395 RRM2_RBM34, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR034220 RBM34_RRM1
IPR034221 RBM34_RRM2
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8C5L7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALGGEERKR RKGSERRQSS GDGVSCAASD YLVGQVADSL RGGPRPPGGG
60 70 80 90 100
TGRLAALFST AEPSAPPVFV PVPQETSKKR KLDDDDDDEE ESVSQTKKPV
110 120 130 140 150
LQEPSRKVKV KKLSDADKRL ANRESALASA DLEEELHQDQ GQGRRRRSQS
160 170 180 190 200
RGKVADGEAL DVALSLAKDG GQRTKIPVNP EEERLKNERT VFVGNLPVTC
210 220 230 240 250
NKKKLKSFFK EYGQVESVRF RSVMPAEGTL TKKLAAIKRK FHPDQKSINA
260 270 280 290 300
YVVFKDESAA AKALQRNGAQ IAEGFRIRVD LASETASRDK RSVFVGNLPY
310 320 330 340 350
KIEDSALEEH FLDCGSIVAV RIVRNPLTGV GRGFGYVLFE NTDAVHLALK
360 370
LNNSELMGRK LRVMRSVNKE KLKQQ
Length:375
Mass (Da):41,326
Last modified:March 1, 2003 - v1
Checksum:i05CE283C0C89EFC2
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B2RUP0B2RUP0_MOUSE
RNA binding motif protein 34
Rbm34 mCG_10092
442Annotation score:
A0A1D5RLR3A0A1D5RLR3_MOUSE
RNA-binding protein 34
Rbm34
422Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078099 mRNA Translation: BAC37124.1
RefSeqiNP_766350.2, NM_172762.2
UniGeneiMm.28199

Genome annotation databases

GeneIDi52202
KEGGimmu:52202

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078099 mRNA Translation: BAC37124.1
RefSeqiNP_766350.2, NM_172762.2
UniGeneiMm.28199

3D structure databases

ProteinModelPortaliQ8C5L7
SMRiQ8C5L7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi206450, 2 interactors
STRINGi10090.ENSMUSP00000048450

PTM databases

iPTMnetiQ8C5L7
PhosphoSitePlusiQ8C5L7

Proteomic databases

EPDiQ8C5L7
MaxQBiQ8C5L7
PaxDbiQ8C5L7
PeptideAtlasiQ8C5L7
PRIDEiQ8C5L7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi52202
KEGGimmu:52202

Organism-specific databases

CTDi23029
MGIiMGI:1098653 Rbm34

Phylogenomic databases

eggNOGiKOG0118 Eukaryota
COG0724 LUCA
HOVERGENiHBG052167
InParanoidiQ8C5L7
KOiK14837

Miscellaneous databases

PROiPR:Q8C5L7
SOURCEiSearch...

Gene expression databases

CleanExiMM_RBM34

Family and domain databases

CDDicd12394 RRM1_RBM34, 1 hit
cd12395 RRM2_RBM34, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR034220 RBM34_RRM1
IPR034221 RBM34_RRM2
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiRBM34_MOUSE
AccessioniPrimary (citable) accession number: Q8C5L7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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