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Entry version 111 (08 May 2019)
Sequence version 2 (24 Jul 2007)
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Protein

NAD kinase 2, mitochondrial

Gene

Nadk2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial NAD+ kinase that phosphorylates NAD+ to yield NADP+. Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by NADH, NADPH and NADP+.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-196807 Nicotinate metabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NAD kinase 2, mitochondrial (EC:2.7.1.23)
Alternative name(s):
Mitochondrial NAD kinase
NAD kinase domain-containing protein 1, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nadk2
Synonyms:Mnadk, Nadkd1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915896 Nadk2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 50MitochondrionSequence analysisAdd BLAST50
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000029629351 – 452NAD kinase 2, mitochondrialAdd BLAST402

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei64N6-acetyllysine; alternateCombined sources1
Modified residuei64N6-succinyllysine; alternateCombined sources1
Modified residuei176PhosphoserineBy similarity1
Modified residuei312N6-succinyllysineCombined sources1
Modified residuei327N6-acetyllysine; alternateCombined sources1
Modified residuei327N6-succinyllysine; alternateCombined sources1
Modified residuei377PhosphoserineBy similarity1
Modified residuei407N6-acetyllysineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8C5H8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8C5H8

PeptideAtlas

More...
PeptideAtlasi
Q8C5H8

PRoteomics IDEntifications database

More...
PRIDEi
Q8C5H8

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
Q8C5H8
Q9CTE4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8C5H8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8C5H8

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8C5H8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022253 Expressed in 240 organ(s), highest expression level in retina

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8C5H8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8C5H8 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000068318

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8C5H8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NAD kinase family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4180 Eukaryota
ENOG410XQA4 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006320

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8C5H8

KEGG Orthology (KO)

More...
KOi
K00858

Identification of Orthologs from Complete Genome Data

More...
OMAi
GEFRWQW

Database of Orthologous Groups

More...
OrthoDBi
1416565at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8C5H8

TreeFam database of animal gene trees

More...
TreeFami
TF314077

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017438 ATP-NAD_kinase_N
IPR016064 NAD/diacylglycerol_kinase_sf
IPR002504 NADK
IPR012355 NADK2_mit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01513 NAD_kinase, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017565 Kin_ATP-NAD_euk, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF111331 SSF111331, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8C5H8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTCYRGFLLG SCRRVAGGRA ALRGSGSGAD GRRHLGHGQP RELAGGGSPA
60 70 80 90 100
DGGFRPSRVV VVAKTTRYEF EQQRYRYAEL SEEDLKQLLA LKGSSYSGLL
110 120 130 140 150
ERHHIHTKNV EHIIDSLRDE GIEVRLVKRR EYDEETVRWA DAVIAAGGDG
160 170 180 190 200
TMLLAASKVL DRLKPVIGVN TDPERSEGHL CLPVRYTHSF PEALRRFSRG
210 220 230 240 250
EFRWLWRQRI RLYLEGTGIN PTPVDLHEQQ LSLNQHSRAF NIERAHDERS
260 270 280 290 300
EASGPQLLPV RALNEVFIGE SLSSRMPYCW AVAVDNLRRD IPNLKGLASY
310 320 330 340 350
YEISVDDGPW EKQKSSGLNL CTGTGSKAWS FNINRVAAQA VEDVLHIARR
360 370 380 390 400
QGNLTLPLNK DLVEKVTNEY NESLLYSPEE PKILFSIREP IANRVFSSSR
410 420 430 440 450
QRCFSSKVCV RSRCWDACMV VDGGTSFEFN DGAIASMMIN KEDELRTVIL

EQ
Length:452
Mass (Da):50,859
Last modified:July 24, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC0FC67A5BA762D1B
GO
Isoform 2 (identifier: Q8C5H8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     276-297: Missing.
     408-452: Missing.

Show »
Length:385
Mass (Da):43,309
Checksum:iA7E10B3ABE5699D4
GO
Isoform 3 (identifier: Q8C5H8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     276-297: Missing.

Show »
Length:430
Mass (Da):48,332
Checksum:i0B92E5E4D3234688
GO
Isoform 4 (identifier: Q8C5H8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     175-202: Missing.
     276-297: Missing.

Note: No experimental confirmation available.
Show »
Length:402
Mass (Da):45,001
Checksum:iE6B139A5248DEF09
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Z4YK42Z4YK42_MOUSE
NAD kinase 2, mitochondrial
Nadk2
401Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WQI8A0A087WQI8_MOUSE
NAD kinase 2, mitochondrial
Nadk2
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB23041 differs from that shown. Reason: Frameshift at position 80.Curated
The sequence BAE28780 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti62V → G in BAB23041 (PubMed:16141072).Curated1
Sequence conflicti81S → P in BAB23041 (PubMed:16141072).Curated1
Sequence conflicti207R → S in BAB23041 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027194175 – 202Missing in isoform 4. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_027195276 – 297Missing in isoform 2, isoform 3 and isoform 4. 1 PublicationAdd BLAST22
Alternative sequenceiVSP_027196408 – 452Missing in isoform 2. 1 PublicationAdd BLAST45

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK003858 mRNA Translation: BAB23041.1 Frameshift.
AK046666 mRNA No translation available.
AK078318 mRNA Translation: BAC37218.1
AK149267 mRNA Translation: BAE28780.1 Different initiation.
AK162601 mRNA Translation: BAE36982.1

NCBI Reference Sequences

More...
RefSeqi
NP_001035485.2, NM_001040395.4 [Q8C5H8-3]
NP_001078879.1, NM_001085410.2 [Q8C5H8-1]
NP_001273184.1, NM_001286255.1 [Q8C5H8-4]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000067760; ENSMUSP00000068318; ENSMUSG00000022253 [Q8C5H8-1]
ENSMUST00000100790; ENSMUSP00000098354; ENSMUSG00000022253 [Q8C5H8-3]
ENSMUST00000213299; ENSMUSP00000149659; ENSMUSG00000111527 [Q8C5H8-1]
ENSMUST00000217358; ENSMUSP00000150501; ENSMUSG00000111527 [Q8C5H8-4]
ENSMUST00000229627; ENSMUSP00000155724; ENSMUSG00000111527 [Q8C5H8-4]
ENSMUST00000229949; ENSMUSP00000155273; ENSMUSG00000111527 [Q8C5H8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68646

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68646

UCSC genome browser

More...
UCSCi
uc029sno.2 mouse [Q8C5H8-1]
uc029snp.2 mouse [Q8C5H8-3]
uc033gta.1 mouse [Q8C5H8-2]
uc033gtb.1 mouse [Q8C5H8-4]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003858 mRNA Translation: BAB23041.1 Frameshift.
AK046666 mRNA No translation available.
AK078318 mRNA Translation: BAC37218.1
AK149267 mRNA Translation: BAE28780.1 Different initiation.
AK162601 mRNA Translation: BAE36982.1
RefSeqiNP_001035485.2, NM_001040395.4 [Q8C5H8-3]
NP_001078879.1, NM_001085410.2 [Q8C5H8-1]
NP_001273184.1, NM_001286255.1 [Q8C5H8-4]

3D structure databases

SMRiQ8C5H8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000068318

PTM databases

iPTMnetiQ8C5H8
PhosphoSitePlusiQ8C5H8
SwissPalmiQ8C5H8

2D gel databases

REPRODUCTION-2DPAGEiQ8C5H8
Q9CTE4

Proteomic databases

jPOSTiQ8C5H8
PaxDbiQ8C5H8
PeptideAtlasiQ8C5H8
PRIDEiQ8C5H8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000067760; ENSMUSP00000068318; ENSMUSG00000022253 [Q8C5H8-1]
ENSMUST00000100790; ENSMUSP00000098354; ENSMUSG00000022253 [Q8C5H8-3]
ENSMUST00000213299; ENSMUSP00000149659; ENSMUSG00000111527 [Q8C5H8-1]
ENSMUST00000217358; ENSMUSP00000150501; ENSMUSG00000111527 [Q8C5H8-4]
ENSMUST00000229627; ENSMUSP00000155724; ENSMUSG00000111527 [Q8C5H8-4]
ENSMUST00000229949; ENSMUSP00000155273; ENSMUSG00000111527 [Q8C5H8-1]
GeneIDi68646
KEGGimmu:68646
UCSCiuc029sno.2 mouse [Q8C5H8-1]
uc029snp.2 mouse [Q8C5H8-3]
uc033gta.1 mouse [Q8C5H8-2]
uc033gtb.1 mouse [Q8C5H8-4]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
133686
MGIiMGI:1915896 Nadk2

Phylogenomic databases

eggNOGiKOG4180 Eukaryota
ENOG410XQA4 LUCA
GeneTreeiENSGT00390000006320
InParanoidiQ8C5H8
KOiK00858
OMAiGEFRWQW
OrthoDBi1416565at2759
PhylomeDBiQ8C5H8
TreeFamiTF314077

Enzyme and pathway databases

ReactomeiR-MMU-196807 Nicotinate metabolism

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8C5H8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000022253 Expressed in 240 organ(s), highest expression level in retina
ExpressionAtlasiQ8C5H8 baseline and differential
GenevisibleiQ8C5H8 MM

Family and domain databases

Gene3Di3.40.50.10330, 1 hit
InterProiView protein in InterPro
IPR017438 ATP-NAD_kinase_N
IPR016064 NAD/diacylglycerol_kinase_sf
IPR002504 NADK
IPR012355 NADK2_mit
PfamiView protein in Pfam
PF01513 NAD_kinase, 1 hit
PIRSFiPIRSF017565 Kin_ATP-NAD_euk, 1 hit
SUPFAMiSSF111331 SSF111331, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNAKD2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C5H8
Secondary accession number(s): Q3TRP5, Q3UEY1, Q9CTE4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: May 8, 2019
This is version 111 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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