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Entry version 118 (02 Jun 2021)
Sequence version 1 (01 Mar 2003)
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Protein

DENN domain-containing protein 2A

Gene

Dennd2a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factor
Biological processProtein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DENN domain-containing protein 2A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dennd2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444961, Dennd2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002426831 – 1000DENN domain-containing protein 2AAdd BLAST1000

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei544PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8C4S8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8C4S8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8C4S8

PRoteomics IDEntifications database

More...
PRIDEi
Q8C4S8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
279369

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8C4S8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8C4S8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000038456, Expressed in floor plate of midbrain and 222 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8C4S8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8C4S8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
229109, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000045367

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8C4S8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8C4S8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini559 – 708uDENNPROSITE-ProRule annotationAdd BLAST150
Domaini730 – 863cDENNPROSITE-ProRule annotationAdd BLAST134
Domaini865 – 960dDENNPROSITE-ProRule annotationAdd BLAST96

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 155DisorderedSequence analysisAdd BLAST155
Regioni174 – 328DisorderedSequence analysisAdd BLAST155
Regioni427 – 464DisorderedSequence analysisAdd BLAST38
Regioni491 – 525DisorderedSequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 48Polar residuesSequence analysisAdd BLAST16
Compositional biasi59 – 116Basic and acidic residuesSequence analysisAdd BLAST58
Compositional biasi138 – 153Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi193 – 240Basic and acidic residuesSequence analysisAdd BLAST48
Compositional biasi262 – 280Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi288 – 306Pro residuesSequence analysisAdd BLAST19
Compositional biasi442 – 460Polar residuesSequence analysisAdd BLAST19
Compositional biasi508 – 525Basic and acidic residuesSequence analysisAdd BLAST18

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3569, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182931

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008960_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8C4S8

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPIFFRQ

Database of Orthologous Groups

More...
OrthoDBi
138384at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8C4S8

TreeFam database of animal gene trees

More...
TreeFami
TF320336

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.11500, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001194, cDENN_dom
IPR005112, dDENN_dom
IPR043153, DENN_C
IPR037516, Tripartite_DENN
IPR005113, uDENN_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03455, dDENN, 1 hit
PF02141, DENN, 1 hit
PF03456, uDENN, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00801, dDENN, 1 hit
SM00799, DENN, 1 hit
SM00800, uDENN, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50211, DENN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8C4S8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEARVDMLS SNMIISGPAA DLGAKEASRP WKKQLNSVPN SGPSARARAQ
60 70 80 90 100
PQPLSIKDKI SKWEGKKEPP ASDPARQTDG QEDHLPSCKV ERRGSELTRT
110 120 130 140 150
KNGMRLETER LQNDSRARTV CQDTEQLPGP RPIDGQPELS QHRGRELKPS
160 170 180 190 200
DLRFQSDHLS VLRQVKRLEK ALKDGSAGLD PQMPGTCYSP HCLPDKTEED
210 220 230 240 250
LPSLESHEKG GVLAAGRRAH HLEVREPGPE ISEDWKGQES VYRGSRWYPP
260 270 280 290 300
KPFINPVPKP RRTFKHAGEG DKDVSPGISF KKEKRNLPPL PSLPPPPPPL
310 320 330 340 350
PSSPPPTSVN RRLWTGRQRP SADHRKSYEF EDLLQSSSEN SRVDWYAQTK
360 370 380 390 400
LGLTRTLSEE NVYEDILDPP MKENPYEDVE LHGRCLGKKC VLTFPASPTS
410 420 430 440 450
SIPDTSTKQS LSKSAFFRQN SERRNLKLLD TRKLSRDGAG SPLRTSPPST
460 470 480 490 500
PSSPDDTFFN LGDLQNGRKK KKIPRLVLRI NAIYEARRGK KRVKRLSQST
510 520 530 540 550
ESNSGKVTDE NSESDSDTEE KLKAHSQRLV NVKSRLKQAP RYSSLDRDLI
560 570 580 590 600
EYQERQLFEY FVVVSLHKKQ AGAAYVPELT QQFPLKLEKS FKFMREAEDQ
610 620 630 640 650
LKAIPQFCFP DAKDWAPVQE FTSETFSFVL TGEDGSRRFG YCRRLLPGGK
660 670 680 690 700
GKRLPEVYCI VSRLGCFSLF SKILDEVEKR RGISPALVQP LMRSVMEAPF
710 720 730 740 750
PALGKTIIVK NFLPGSGTEV IELCRPLDSR LEHVDFESLF SSLSVRHLVS
760 770 780 790 800
VFASLLLERR VIFIADKLST LSKCCHAMVA LIYPFSWQHT YIPVLPPAMI
810 820 830 840 850
DIVCSPTPFL IGLLSSSLPL LRELPLEEVL VVDLINDRFL RQMEDEDSIL
860 870 880 890 900
PRKLQVALEH ILEQRNDLAC DQDGGPLDCV HGPESSSLSE VVSEAFVRFF
910 920 930 940 950
VEIVGHYPLF LTSGEERSLQ REAFRKAVSS KSLRRFLEVF METQTFRGFI
960 970 980 990 1000
QERELRRQDA KGLFEVRAQE YLETLPSGEH SGVNKFLKGL GNKMKFLHKK
Length:1,000
Mass (Da):113,094
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8866696B3B25303B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z1C6D3Z1C6_MOUSE
DENN domain-containing protein 2A
Dennd2a
420Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE22660 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti67K → E in BAE36008 (PubMed:16141072).Curated1
Sequence conflicti122Q → L in BAE39403 (PubMed:16141072).Curated1
Sequence conflicti523K → E in BAE39403 (PubMed:16141072).Curated1
Sequence conflicti612A → V in BAE22660 (PubMed:16141072).Curated1
Sequence conflicti620E → G in BAE39403 (PubMed:16141072).Curated1
Sequence conflicti698A → P in BAE22660 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK081176 mRNA Translation: BAC38157.1
AK135781 mRNA Translation: BAE22660.1 Different initiation.
AK160784 mRNA Translation: BAE36008.1
AK167298 mRNA Translation: BAE39403.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20023.1

NCBI Reference Sequences

More...
RefSeqi
NP_766065.1, NM_172477.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000036877; ENSMUSP00000045367; ENSMUSG00000038456

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
209773

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:209773

UCSC genome browser

More...
UCSCi
uc009blx.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK081176 mRNA Translation: BAC38157.1
AK135781 mRNA Translation: BAE22660.1 Different initiation.
AK160784 mRNA Translation: BAE36008.1
AK167298 mRNA Translation: BAE39403.1
CCDSiCCDS20023.1
RefSeqiNP_766065.1, NM_172477.4

3D structure databases

SMRiQ8C4S8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi229109, 2 interactors
STRINGi10090.ENSMUSP00000045367

PTM databases

iPTMnetiQ8C4S8
PhosphoSitePlusiQ8C4S8

Proteomic databases

jPOSTiQ8C4S8
MaxQBiQ8C4S8
PaxDbiQ8C4S8
PRIDEiQ8C4S8
ProteomicsDBi279369

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32452, 39 antibodies

The DNASU plasmid repository

More...
DNASUi
209773

Genome annotation databases

EnsembliENSMUST00000036877; ENSMUSP00000045367; ENSMUSG00000038456
GeneIDi209773
KEGGimmu:209773
UCSCiuc009blx.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27147
MGIiMGI:2444961, Dennd2a

Phylogenomic databases

eggNOGiKOG3569, Eukaryota
GeneTreeiENSGT00950000182931
HOGENOMiCLU_008960_1_1_1
InParanoidiQ8C4S8
OMAiKPIFFRQ
OrthoDBi138384at2759
PhylomeDBiQ8C4S8
TreeFamiTF320336

Enzyme and pathway databases

ReactomeiR-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
209773, 5 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Dennd2a, mouse

Protein Ontology

More...
PROi
PR:Q8C4S8
RNActiQ8C4S8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000038456, Expressed in floor plate of midbrain and 222 other tissues
ExpressionAtlasiQ8C4S8, baseline and differential
GenevisibleiQ8C4S8, MM

Family and domain databases

Gene3Di3.40.50.11500, 1 hit
InterProiView protein in InterPro
IPR001194, cDENN_dom
IPR005112, dDENN_dom
IPR043153, DENN_C
IPR037516, Tripartite_DENN
IPR005113, uDENN_dom
PfamiView protein in Pfam
PF03455, dDENN, 1 hit
PF02141, DENN, 1 hit
PF03456, uDENN, 1 hit
SMARTiView protein in SMART
SM00801, dDENN, 1 hit
SM00799, DENN, 1 hit
SM00800, uDENN, 1 hit
PROSITEiView protein in PROSITE
PS50211, DENN, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDEN2A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C4S8
Secondary accession number(s): Q3TJU2, Q3TUG3, Q3UXA3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2003
Last modified: June 2, 2021
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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