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Entry version 115 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
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Protein

C2H2-type domain-containing protein

Gene

Zfp106

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C2H2-type domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zfp106Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1270153, Zfp106

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q8C235

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini7 – 29C2H2-typeInterPro annotationAdd BLAST23

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni68 – 187DisorderedSequence analysisAdd BLAST120
Regioni287 – 325DisorderedSequence analysisAdd BLAST39
Regioni338 – 362DisorderedSequence analysisAdd BLAST25
Regioni410 – 438DisorderedSequence analysisAdd BLAST29
Regioni453 – 617DisorderedSequence analysisAdd BLAST165

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi76 – 90AcidicSequence analysisAdd BLAST15
Compositional biasi91 – 108PolyampholyteSequence analysisAdd BLAST18
Compositional biasi120 – 164PolyampholyteSequence analysisAdd BLAST45
Compositional biasi165 – 179PolarSequence analysisAdd BLAST15
Compositional biasi287 – 314PolyampholyteSequence analysisAdd BLAST28
Compositional biasi338 – 355PolarSequence analysisAdd BLAST18
Compositional biasi502 – 526PolarSequence analysisAdd BLAST25
Compositional biasi538 – 552PolyampholyteSequence analysisAdd BLAST15
Compositional biasi553 – 577PolarSequence analysisAdd BLAST25
Compositional biasi578 – 592PolyampholyteSequence analysisAdd BLAST15
Compositional biasi593 – 615PolarSequence analysisAdd BLAST23

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR042622, Znf106
IPR013087, Znf_C2H2_type

The PANTHER Classification System

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PANTHERi
PTHR14435, PTHR14435, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8C235-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRERKCILC HIVYGSKKEM DEHMRSMLHH RELENLKGRD ISHECRVCRV
60 70 80 90 100
TEVGLSAYAK HISGQLHKDN VDAQEREDDG KEEEEEEYFD KELVQLIQER
110 120 130 140 150
KEQSRQDEPP SNSQEVNSDD RQPQWRREDR IPYQDRESYS QPPRHHRGPP
160 170 180 190 200
QRDWKWEKDG FNSTRKNSFP HSLRNSGGPR GSSVWHKGAT RGSSTWFLNH
210 220 230 240 250
SNSGGGWHSN NGMVDWNYNG TGRNSSWHSE GTGGFPSWHM NNSNGNWKSS
260 270 280 290 300
VRSTNSWNYN GPGDKFQQGR NRNPNYQMED MTKMWNKKSN KPSKYSQERC
310 320 330 340 350
KWQRQDRDKA AKYRSPPEGY ASDTFPSEGL LEFNFEQRES QTTKQTDTAA
360 370 380 390 400
SKINGKNGTK ARDKFRRWTP YPSQKTLDLQ SALKEVIGSK SDTLEKPLFN
410 420 430 440 450
FSLITAGLRK PVDKTSNPPV IKTQKAGPPG SPSHKAISDG TAFCEVPRAC
460 470 480 490 500
PITEQSEPHQ KSNKIPLLKS PLLPLPTPKS GPHKQNLKNR SKNKETKSFP
510 520 530 540 550
SGDHSHLLNT STLEGSHGSS YTSKSRGLCP RVLKENKTVS GTQKEPDEKL
560 570 580 590 600
NSTSQKAQDT VLQCPKTLQN PLPTTPKRTE NDAKESSVEE SAKDSLSIES
610 620 630 640 650
QPHSAGNSAM TSDAENHGIK SEGVASLTTE VVSCSTHTVD KEQGSQIPGT
660 670 680 690 700
PENLSASPCN STVLQKEAEV QVSAATSPHS GLLLNLKTSL EDAQDNDLVK
710 720 730 740 750
SDGPFETESF EDTSLDAELQ KPDLNNQPPG TLLPELSKLG FPASLQRDLS
760 770 780 790 800
RHISLKSKTG THLPEPNLNS ARRIRNVSGH RKNETEKESG LKPTLRQILN
810 820 830
ASRRNVNWEQ VIQQVTKKKQ ELGKGLPRCV PLIPVLGFF
Length:839
Mass (Da):94,147
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6D6FFD76E32A3289
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK089359 mRNA Translation: BAC40854.1
AK155019 mRNA Translation: BAE32992.1

Genome annotation databases

UCSC genome browser

More...
UCSCi
uc008lwe.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK089359 mRNA Translation: BAC40854.1
AK155019 mRNA Translation: BAE32992.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ8C235

Genome annotation databases

UCSCiuc008lwe.1, mouse

Organism-specific databases

MGIiMGI:1270153, Zfp106

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Zfp106, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR042622, Znf106
IPR013087, Znf_C2H2_type
PANTHERiPTHR14435, PTHR14435, 1 hit
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8C235_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C235
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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