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Protein

Serine-rich coiled-coil domain-containing protein 1

Gene

Ccser1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Serine-rich coiled-coil domain-containing protein 1
Alternative name(s):
Coiled-coil serine-rich protein 1
Gene namesi
Name:Ccser1
Synonyms:Fam190a, Kiaa1680
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3045354 Ccser1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003492931 – 895Serine-rich coiled-coil domain-containing protein 1Add BLAST895

Proteomic databases

PaxDbiQ8C0C4
PRIDEiQ8C0C4

PTM databases

iPTMnetiQ8C0C4
PhosphoSitePlusiQ8C0C4

Expressioni

Gene expression databases

BgeeiENSMUSG00000039578
ExpressionAtlasiQ8C0C4 baseline and differential
GenevisibleiQ8C0C4 MM

Interactioni

Protein-protein interaction databases

IntActiQ8C0C4, 1 interactor
MINTiQ8C0C4
STRINGi10090.ENSMUSP00000040251

Structurei

3D structure databases

ProteinModelPortaliQ8C0C4
SMRiQ8C0C4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili675 – 705Sequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi28 – 202Ser-richAdd BLAST175

Sequence similaritiesi

Belongs to the CCSER family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IEYT Eukaryota
ENOG410YA7F LUCA
GeneTreeiENSGT00730000111248
HOGENOMiHOG000113174
InParanoidiQ8C0C4
OMAiYHSVVSC
OrthoDBiEOG091G0340
PhylomeDBiQ8C0C4
TreeFamiTF331021

Family and domain databases

InterProiView protein in InterPro
IPR029627 CCSER
IPR029628 CCSER1
PANTHERiPTHR22461 PTHR22461, 1 hit
PTHR22461:SF1 PTHR22461:SF1, 1 hit

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8C0C4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGDSGSRRCT LVSRLPIFRK SINRRHDSLP SSPSSSNTAG VHSSSPSSTN
60 70 80 90 100
SSSGSTGKRR SIFRAPSISF HHKKGSEPKP EPTEQNLSIS NGAQPSHSNM
110 120 130 140 150
QKLSLEEHVK TRGRHSVGFS SSRSKKITRS LTEDFEREKE PSTNKNVFIN
160 170 180 190 200
CLSSGRSEGD DSGFTEEQSR RSIKQSTKKL LPKSFSSHYK FCKSVPQSQS
210 220 230 240 250
TSLIQQPEFS LAIAQYQEQE AALGRPSPSC SVDVTERAGS SLQSPLLSAD
260 270 280 290 300
LTTAQTPSEF LALTEDSLSE ADAFPKSGST ASHCDNFGHN DATSQPTSSL
310 320 330 340 350
TAVSKTKMEF VGTAPCVMSP GRYRLEGRCS TELHSSPETP AGNRREVSLQ
360 370 380 390 400
STELSVGNGS DPETHLPAHH QRGESPLAHA GEPALRTGSP RTLGSYDQHK
410 420 430 440 450
ALAERFKGVH PVSDSRVIPS SGDHVFNKTS YGYEASAAKV LASSLSPYRE
460 470 480 490 500
GRYIERRLRS SSEGTAGSSR MVLKPKDGHV EASSLRKHRT GSSSSKMNSL
510 520 530 540 550
DVLNHLGSCE LDEDDLMLDL EFLEEQNLQP PVCREDSCHS VMSCTAVLLS
560 570 580 590 600
PVDPGKEVNM LEEPKCPEPS KQNLSLRITK DTDQEARCSH VSCMPNSPSA
610 620 630 640 650
DWPQQGVEEN GGIDSLPFRL MLQECTAVKT LLLKMKRVLQ ESDVSPSSST
660 670 680 690 700
TSLPISPLTE EPLPFKDITR DECSMLRLQL KDRDELISQL QAELEKVQHL
710 720 730 740 750
QKAFASRVDK STQTELLGCD GLSLKRLEAV QGGRETTHRN RTMSQSHSTR
760 770 780 790 800
DRKAIHTPTE DRFRYSTADQ TSPYKNICQL PGLCLSNFLK DKELGGVMKH
810 820 830 840 850
TRGNHEAVTS EMTQNSRTTM GQSFLKAAAK PEGLPMFSEK PKDPAALSRQ
860 870 880 890
HSTFTGRFGQ PPRGPISLHT YSRKNVFLHH NLHTTEFQTL GQQDG
Length:895
Mass (Da):98,217
Last modified:September 2, 2008 - v2
Checksum:iF630C3EB4233E4A9
GO
Isoform 2 (identifier: Q8C0C4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     440-485: VLASSLSPYR...KDGHVEASSL → GMQIFLVQKL...IISVKSLLWF
     486-895: Missing.

Show »
Length:485
Mass (Da):52,886
Checksum:i58E5B4FCA6995F0B
GO
Isoform 3 (identifier: Q8C0C4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     721-743: GLSLKRLEAVQGGRETTHRNRTM → TNLKHLGAFRRIIPGINGIPNSY
     744-895: Missing.

Note: No experimental confirmation available.
Show »
Length:743
Mass (Da):81,123
Checksum:i93573157539CD59D
GO

Sequence cautioni

The sequence BAD32509 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti432G → R in BAC27537 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_035320440 – 485VLASS…EASSL → GMQIFLVQKLCTLIFILFEQ LFLRHIVNERHVSFVFIISV KSLLWF in isoform 2. 2 PublicationsAdd BLAST46
Alternative sequenceiVSP_035321486 – 895Missing in isoform 2. 2 PublicationsAdd BLAST410
Alternative sequenceiVSP_035322721 – 743GLSLK…RNRTM → TNLKHLGAFRRIIPGINGIP NSY in isoform 3. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_035323744 – 895Missing in isoform 3. 1 PublicationAdd BLAST152

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK031754 mRNA Translation: BAC27537.1
AK048645 mRNA Translation: BAC33408.1
AC122505 Genomic DNA No translation available.
AC103630 Genomic DNA No translation available.
AC113320 Genomic DNA No translation available.
AC122524 Genomic DNA No translation available.
AC125119 Genomic DNA No translation available.
AC137119 Genomic DNA No translation available.
AC154007 Genomic DNA No translation available.
AC154008 Genomic DNA No translation available.
AC168089 Genomic DNA No translation available.
AC174640 Genomic DNA No translation available.
AC174778 Genomic DNA No translation available.
BC107398 mRNA Translation: AAI07399.1
BC107399 mRNA Translation: AAI07400.1
BC117738 mRNA Translation: AAI17739.1
AK173231 mRNA Translation: BAD32509.1 Different initiation.
CCDSiCCDS51800.1 [Q8C0C4-1]
RefSeqiNP_001157788.1, NM_001164316.1 [Q8C0C4-1]
NP_899133.2, NM_183310.2 [Q8C0C4-1]
XP_006506017.1, XM_006505954.1 [Q8C0C4-3]
UniGeneiMm.150324

Genome annotation databases

EnsembliENSMUST00000045522; ENSMUSP00000040251; ENSMUSG00000039578 [Q8C0C4-1]
ENSMUST00000126214; ENSMUSP00000122894; ENSMUSG00000039578 [Q8C0C4-1]
GeneIDi232035
KEGGimmu:232035
UCSCiuc009cdu.2 mouse [Q8C0C4-2]
uc009cdw.2 mouse [Q8C0C4-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiCCSE1_MOUSE
AccessioniPrimary (citable) accession number: Q8C0C4
Secondary accession number(s): Q3KN97, Q69ZD5, Q8C822
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: February 28, 2018
This is version 94 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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