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Entry version 126 (29 Sep 2021)
Sequence version 2 (27 Jul 2011)
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Protein

Microtubule-associated protein 1S

Gene

Map1s

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis (By similarity).

Involved in the formation of microtubule bundles.

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processApoptosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microtubule-associated protein 1S
Short name:
MAP-1S
Alternative name(s):
BPY2-interacting protein 1
Microtubule-associated protein 8
Cleaved into the following 2 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Map1s
Synonyms:Bpy2ip1, Map8, Mtap1s
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2443304, Map1s

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000019261

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003113821 – 973Microtubule-associated protein 1SAdd BLAST973
ChainiPRO_00003113831 – 742MAP1S heavy chainAdd BLAST742
ChainiPRO_0000311384743 – 973MAP1S light chainAdd BLAST231

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei462PhosphoserineCombined sources1
Modified residuei586PhosphoserineBy similarity1
Modified residuei591PhosphoserineBy similarity1
Modified residuei593PhosphoserineBy similarity1
Modified residuei660PhosphoserineCombined sources1
Modified residuei684PhosphoserineBy similarity1
Modified residuei724PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8C052

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8C052

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8C052

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8C052

PeptideAtlas

More...
PeptideAtlasi
Q8C052

PRoteomics IDEntifications database

More...
PRIDEi
Q8C052

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
252730

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8C052

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8C052

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in ventral and dorsal horns of the spinal cord, hippocampus, cerebral cortex, molecular, Purkinje and granular cell layers of the cerebellum and in dorsal root ganglia of the PNS (at protein level). Expressed in brain, testis, heart, lung, kidney and liver.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in embryo at 10 dpc onwards (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000019261, Expressed in brain and 274 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8C052, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8C052, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterodimer of a heavy and a light chain.

Interacts with microtubules and actin. Both MAP1S heavy and light chains interact with microtubules. MAP1S light chain interacts with actin.

Interacts with ESR1, LRPPRC, RASSF1, microtubules and VCY2.

Interacts with WDR47 (via N-terminus of light chain) (By similarity).

Interacts (via C-terminus) with GAN (via Kelch domains).

By similarity3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
234753, 17 interactors

Protein interaction database and analysis system

More...
IntActi
Q8C052, 2 interactors

Molecular INTeraction database

More...
MINTi
Q8C052

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000019405

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8C052, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8C052

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 716Necessary for the microtubule-organizing center localizationBy similarityAdd BLAST716
Regioni452 – 538DisorderedSequence analysisAdd BLAST87
Regioni560 – 853DisorderedSequence analysisAdd BLAST294
Regioni601 – 973Necessary for interaction with RASSF1By similarityAdd BLAST373
Regioni645 – 880Necessary for association with microtubulesAdd BLAST236
Regioni875 – 973Necessary for association with actinAdd BLAST99
Regioni881 – 905Necessary for the mitochondrial aggregation and genome destructionBy similarityAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi567 – 585Pro residuesSequence analysisAdd BLAST19
Compositional biasi605 – 634Polar residuesSequence analysisAdd BLAST30
Compositional biasi687 – 714Polar residuesSequence analysisAdd BLAST28
Compositional biasi737 – 752Pro residuesSequence analysisAdd BLAST16
Compositional biasi766 – 793Polar residuesSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Its C-terminal part of the heavy chain interacts with ESR1 (By similarity). The N-terminus of the heavy chain associates with the C-terminus of the light chain to form the heterodimer complex.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MAP1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3592, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160221

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000285_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8C052

Identification of Orthologs from Complete Genome Data

More...
OMAi
YQETHDR

Database of Orthologous Groups

More...
OrthoDBi
86642at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8C052

TreeFam database of animal gene trees

More...
TreeFami
TF350229

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026074, MAP1
IPR027322, MAP1S
IPR036866, RibonucZ/Hydroxyglut_hydro

The PANTHER Classification System

More...
PANTHERi
PTHR13843, PTHR13843, 2 hits
PTHR13843:SF11, PTHR13843:SF11, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56281, SSF56281, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8C052-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVMAAPEA VEAPSSLLLL VVGGECGCPG LLAYVMEELE RGVRSWEDVD
60 70 80 90 100
PAVCSLDEQL KAFVSRHSAT FSSIVKGQRS LHHRGETLET LVLLNPSDKS
110 120 130 140 150
LCDELRNLLM DPAPHKLLVL AGPCLEETGE LLLQTGGFSA HHFLQVLGDK
160 170 180 190 200
EVQDALASAP AAPALTVSCP TFGDWALLGP VPGLQLRLNP PAQLPASEGL
210 220 230 240 250
RAFLEYVAES LEPPSPFELL EPPAAGGFLR LARPCCYVFP GGLGDAAFFA
260 270 280 290 300
VNGFTVLVNG GSNPKSSFWK LVRHLDRVDA VLVTHAGADS LPGLNSLLRR
310 320 330 340 350
KLAEREAAAG PQGQHEERLR RLLSPALGVV FLNAREAASR LRGGEDEAVC
360 370 380 390 400
ARSLLRSLGI APLPLQRGPQ PSCPTVLFEK LGVGRLELFV LHPPPGDPAA
410 420 430 440 450
PACALLVWQP AAPGDKVVRV LFPGRTPPAR LLDGLQRLQH LPCLRRPVVT
460 470 480 490 500
THDLEAPSRA NSQDSLASRD SARKEPVRGT VGSIANRSTV RREPALATRD
510 520 530 540 550
QKKDTRSGPT QPTARDTRRS GPGVVNTKPR VSQNGPRAPV LAAPLTAPVA
560 570 580 590 600
ECPGEAENIL ESERPPAPSP TLSPAQSPPP TAPGNSPERL SLSPLRPEPA
610 620 630 640 650
PDASPSATTP TLTTPSLPAE LGSPHSTEVD ESLSVSFEQV LPAGDPGLSL
660 670 680 690 700
PLRLARRSTS PHDVDLCLVS PCEFSHRKPP PPASPGSSDS SARSQERPPE
710 720 730 740 750
TPPTSVSESL PTLSDSDPVP VADSDDDAGS ESAARDPPPT PRVPPPLPDV
760 770 780 790 800
PGICMVDPEA LPPRARQPLN TTNPSRSRKA PARPSSASAT PRAATVAAKT
810 820 830 840 850
KGPAGDRNRP LSARSEPADR PGRVPLTRKP SVPKTVPKMA SATRLSSGPS
860 870 880 890 900
GRPAPLAAGS PVYLDLAYLP GGGAGHLDQN FFLRVRALCY VISGQGQRQE
910 920 930 940 950
EGLRAVLDAL LAGKRQWDLD LQVTLIPTFD SAVMHRWYEE THAQHQALGI
960 970
RVLGSGSLVS MQDEAFPACK VEF
Length:973
Mass (Da):102,939
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DD3E1A43F70E8DD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5RLY6A0A1D5RLY6_MOUSE
Microtubule-associated protein 1S
Map1s
864Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RMF1A0A1D5RMF1_MOUSE
Microtubule-associated protein 1S
Map1s
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RML0A0A1D5RML0_MOUSE
Microtubule-associated protein 1S
Map1s
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RMG7A0A1D5RMG7_MOUSE
Microtubule-associated protein 1S
Map1s
239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH52828 differs from that shown. Contaminating sequence. At the N-terminus.Curated
The sequence AAH52828 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti475E → G in AAH52828 (PubMed:15489334).Curated1
Sequence conflicti680P → T in ABD47683 (PubMed:16297881).Curated1
Sequence conflicti680P → T in BAC27800 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ387862 mRNA Translation: ABD47683.1
AK032300 mRNA Translation: BAC27800.1
AK162124 mRNA Translation: BAE36739.1
AC019302 Genomic DNA No translation available.
BC052828 mRNA Translation: AAH52828.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS22387.1

NCBI Reference Sequences

More...
RefSeqi
NP_766601.2, NM_173013.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000019405; ENSMUSP00000019405; ENSMUSG00000019261

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
270058

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:270058

UCSC genome browser

More...
UCSCi
uc009mcd.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ387862 mRNA Translation: ABD47683.1
AK032300 mRNA Translation: BAC27800.1
AK162124 mRNA Translation: BAE36739.1
AC019302 Genomic DNA No translation available.
BC052828 mRNA Translation: AAH52828.1 Different initiation.
CCDSiCCDS22387.1
RefSeqiNP_766601.2, NM_173013.3

3D structure databases

SMRiQ8C052
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi234753, 17 interactors
IntActiQ8C052, 2 interactors
MINTiQ8C052
STRINGi10090.ENSMUSP00000019405

PTM databases

iPTMnetiQ8C052
PhosphoSitePlusiQ8C052

Proteomic databases

EPDiQ8C052
jPOSTiQ8C052
MaxQBiQ8C052
PaxDbiQ8C052
PeptideAtlasiQ8C052
PRIDEiQ8C052
ProteomicsDBi252730

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27783, 194 antibodies

The DNASU plasmid repository

More...
DNASUi
270058

Genome annotation databases

EnsembliENSMUST00000019405; ENSMUSP00000019405; ENSMUSG00000019261
GeneIDi270058
KEGGimmu:270058
UCSCiuc009mcd.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55201
MGIiMGI:2443304, Map1s
VEuPathDBiHostDB:ENSMUSG00000019261

Phylogenomic databases

eggNOGiKOG3592, Eukaryota
GeneTreeiENSGT00940000160221
HOGENOMiCLU_000285_2_0_1
InParanoidiQ8C052
OMAiYQETHDR
OrthoDBi86642at2759
PhylomeDBiQ8C052
TreeFamiTF350229

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
270058, 5 hits in 62 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Map1s, mouse

Protein Ontology

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PROi
PR:Q8C052
RNActiQ8C052, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000019261, Expressed in brain and 274 other tissues
ExpressionAtlasiQ8C052, baseline and differential
GenevisibleiQ8C052, MM

Family and domain databases

InterProiView protein in InterPro
IPR026074, MAP1
IPR027322, MAP1S
IPR036866, RibonucZ/Hydroxyglut_hydro
PANTHERiPTHR13843, PTHR13843, 2 hits
PTHR13843:SF11, PTHR13843:SF11, 2 hits
SUPFAMiSSF56281, SSF56281, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAP1S_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C052
Secondary accession number(s): E9QKR8, Q3TSD6, Q7TMW8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: July 27, 2011
Last modified: September 29, 2021
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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