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Entry version 144 (08 May 2019)
Sequence version 2 (26 Apr 2004)
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Protein

Pogo transposable element with ZNF domain

Gene

Pogz

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri372 – 394C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri527 – 550C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri557 – 580C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri587 – 610C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri616 – 638C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri644 – 667C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri767 – 790C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri811 – 836C2H2-type 9PROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Pogo transposable element with ZNF domain
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pogz
Synonyms:Kiaa0461
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2442117 Pogz

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000472251 – 1409Pogo transposable element with ZNF domainAdd BLAST1409

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki319Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei333PhosphoserineBy similarity1
Cross-linki356Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei360PhosphoserineBy similarity1
Cross-linki419Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei422PhosphoserineBy similarity1
Modified residuei436PhosphothreonineBy similarity1
Modified residuei442PhosphoserineBy similarity1
Cross-linki446Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei460PhosphothreonineBy similarity1
Cross-linki486Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki626Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki674Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki797Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki879Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1334PhosphoserineBy similarity1
Modified residuei1360PhosphoserineBy similarity1
Modified residuei1366PhosphoserineBy similarity1
Modified residuei1391PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BZH4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BZH4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8BZH4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BZH4

PRoteomics IDEntifications database

More...
PRIDEi
Q8BZH4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BZH4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BZH4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000038902 Expressed in 247 organ(s), highest expression level in cardiac ventricle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BZH4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BZH4 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CBX1, CBX3, MAD2L2 and CHAMP1.

Interacts with CBX5; POGZ competes with PXVXL motif-containing proteins such as INCENP and TRIM28 for interaction with CBX5.

Interacts with PSIP1 isoform 1 (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
230865, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q8BZH4, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000102891

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BZH4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1011 – 1081HTH CENPB-typePROSITE-ProRule annotationAdd BLAST71
Domaini1113 – 1319DDE-1Sequence analysisAdd BLAST207

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni806 – 846Required for interaction with CBX5By similarityAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1336 – 1364Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi872 – 927Pro-richAdd BLAST56

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri372 – 394C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri491 – 513C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri527 – 550C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri557 – 580C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri587 – 610C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri616 – 638C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri644 – 667C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri767 – 790C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri811 – 836C2H2-type 9PROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
KOG3105 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160649

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000010309

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BZH4

KEGG Orthology (KO)

More...
KOi
K22594

Database of Orthologous Groups

More...
OrthoDBi
105829at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BZH4

TreeFam database of animal gene trees

More...
TreeFami
TF331707

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeobox-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03184 DDE_1, 1 hit
PF03221 HTH_Tnp_Tc5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00674 CENPB, 1 hit
SM00355 ZnF_C2H2, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51253 HTH_CENPB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8BZH4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADTDLFMEC EEEELEPWQK ISDVIEDSVV EDYNSVDKTT SVSVSQQPVS
60 70 80 90 100
APVPIAAHAS VAGHLSTSTT VSNSGAQNSD STKKTLVTLI ANNNAGNTLV
110 120 130 140 150
QQGGQPLILT QNPAPGLGTM VTQPVLRPVQ VMQNANHVTS SPVASQPIFI
160 170 180 190 200
TTQGFPVRNV RPVQNAMNQV GIVLNVQQGQ TVRPITLVPA PGTQFVKPTV
210 220 230 240 250
GVPQVFSQMT PVRPGSTMPV RPTTNTFTTV IPATLTIRST VPQSQSQQTK
260 270 280 290 300
STPSTSTTPT ATQPTSLGQL AGQPPGQSNQ TSNPKLAPSF PSPPAVSIAS
310 320 330 340 350
FVTVKRPGVT GENSNEVAKL VNTLNTVPSL GQSPGPVVVS NNSSAQRTSG
360 370 380 390 400
PESSVKVTSS IPVFDLQDGG RKICPRCNAQ FRVTEALRGH MCYCCPEMVE
410 420 430 440 450
YQKKGKSLDA EPSVPSAAKP SSPEKTAPVT STPSSTPIPA LSPPTKVPEP
460 470 480 490 500
NENAGDAVQT KLIMLVDDFY YGRDGGKAAQ LTSFPKVATS FRCPHCTKRL
510 520 530 540 550
KNNIRFMNHM KHHVELDQQN GEVDGHTICQ HCYRQFSTPF QLQCHLENVH
560 570 580 590 600
SPYESTTKCK ICEWAFESEP LFLQHMKDTH KPGEMPYVCQ VCQYRSSLYS
610 620 630 640 650
EVDVHFRMIH EDTRHLLCPY CLKVFKNGNA FQQHYMRHQK RNVYHCNKCR
660 670 680 690 700
LQFLFAKDKI EHKLQHHKTF RKPKQLEGLK PGTKVTIRAS RGQPRTVPVS
710 720 730 740 750
SNDAPSGTLQ EAAALTSTDP LPVFLYPPVQ RNIQKRAVRK MSVMGRQTCL
760 770 780 790 800
ECSFEIPDFP NHFPTYVHCS LCRYSTCCSR AYANHMINNH VPRKSPKYLA
810 820 830 840 850
LFKNSVSGIK LACTSCTFAT SVGDAMAKHL VFNPSHRSSN ILPRGLSWMS
860 870 880 890 900
HLRPGQASER VFDWSMKNTY LPPPLVPNKA ATVKPVGVTP AEPQELAGPV
910 920 930 940 950
LQALPSPAST ATPPATPTHP QPSALPPSAT EGTECLNVSE QEEGSPVTQD
960 970 980 990 1000
PEPASGGGGG SGVGKKEQLS VKKLRVVLFA LCCNTEQAAE HFRNPQRRIR
1010 1020 1030 1040 1050
RWLRRFQASQ GENLEGKYLS FEAEEKLAEW VLIQREQQLP VNEETLFQKA
1060 1070 1080 1090 1100
TKIGRSLEGG FKISYEWAVR FMLRHHLTPH ARRAVAHTLP KHVAENAGLF
1110 1120 1130 1140 1150
IEFVQRQIHN QDLPLSMIVA IDEISLFLDT EVLSSDDRKE NALQTVGTGE
1160 1170 1180 1190 1200
PWCDVVLAIL ADGTVLPTLV FFRGQANRFA NVPDSILLEA KDSGYSDDEI
1210 1220 1230 1240 1250
MELWSTRVWK KHTACQHSKS MLVMDCHRTH LSEEVLALLS ASSTLPAVVP
1260 1270 1280 1290 1300
AGCSSKIQPL DVCIKRTVKN FLHKKWKEQA REMADAACDS DVLLQLVLVW
1310 1320 1330 1340 1350
LGEVLGVIGD SPELVQRSFL VASVLPGPDG NVNSPTRNAD MQEELIASLE
1360 1370 1380 1390 1400
EQLKLNGEQS EEHSASAPRP RSSPEETVEP ESLHQLFEGE SETESFYGFE

EADLDLMEI
Length:1,409
Mass (Da):154,910
Last modified:April 26, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED08A5E2C1E719A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YUW8D3YUW8_MOUSE
Pogo transposable element with ZNF ...
Pogz
1,314Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YUX1D3YUX1_MOUSE
Pogo transposable element with ZNF ...
Pogz
1,356Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q0VGT3Q0VGT3_MOUSE
Pogo transposable element with ZNF ...
Pogz mCG_13704
1,400Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7D0L1F7D0L1_MOUSE
Pogo transposable element with ZNF ...
Pogz
54Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti513 – 515HVE → TRP in AAH32176 (PubMed:15489334).Curated3
Sequence conflicti1342Q → E in BAC29003 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK030880 mRNA Translation: BAC27169.1
AK035255 mRNA Translation: BAC29003.1
BC032176 mRNA Translation: AAH32176.1
BC096492 mRNA Translation: AAH96492.1
AK122288 mRNA Translation: BAC65570.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17596.1

NCBI Reference Sequences

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RefSeqi
NP_766271.2, NM_172683.3
XP_011238392.1, XM_011240090.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000107270; ENSMUSP00000102891; ENSMUSG00000038902

Database of genes from NCBI RefSeq genomes

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GeneIDi
229584

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:229584

UCSC genome browser

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UCSCi
uc008qhc.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK030880 mRNA Translation: BAC27169.1
AK035255 mRNA Translation: BAC29003.1
BC032176 mRNA Translation: AAH32176.1
BC096492 mRNA Translation: AAH96492.1
AK122288 mRNA Translation: BAC65570.1
CCDSiCCDS17596.1
RefSeqiNP_766271.2, NM_172683.3
XP_011238392.1, XM_011240090.2

3D structure databases

SMRiQ8BZH4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi230865, 6 interactors
IntActiQ8BZH4, 1 interactor
STRINGi10090.ENSMUSP00000102891

PTM databases

iPTMnetiQ8BZH4
PhosphoSitePlusiQ8BZH4

Proteomic databases

EPDiQ8BZH4
jPOSTiQ8BZH4
MaxQBiQ8BZH4
PaxDbiQ8BZH4
PRIDEiQ8BZH4

Genome annotation databases

EnsembliENSMUST00000107270; ENSMUSP00000102891; ENSMUSG00000038902
GeneIDi229584
KEGGimmu:229584
UCSCiuc008qhc.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
23126
MGIiMGI:2442117 Pogz

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
KOG3105 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000160649
HOGENOMiHOG000010309
InParanoidiQ8BZH4
KOiK22594
OrthoDBi105829at2759
PhylomeDBiQ8BZH4
TreeFamiTF331707

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Pogz mouse

Protein Ontology

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PROi
PR:Q8BZH4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000038902 Expressed in 247 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiQ8BZH4 baseline and differential
GenevisibleiQ8BZH4 MM

Family and domain databases

InterProiView protein in InterPro
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeobox-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF03184 DDE_1, 1 hit
PF03221 HTH_Tnp_Tc5, 1 hit
SMARTiView protein in SMART
SM00674 CENPB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS51253 HTH_CENPB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOGZ_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BZH4
Secondary accession number(s): Q4VA94
, Q80TZ8, Q8C0K1, Q8K294
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 26, 2004
Last modified: May 8, 2019
This is version 144 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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