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Entry version 115 (29 Sep 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Putative Polycomb group protein ASXL2

Gene

Asxl2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3 (By similarity).

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri1332 – 1369PHD-type; atypicalAdd BLAST38

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5689603, UCH proteinases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative Polycomb group protein ASXL2
Alternative name(s):
Additional sex combs-like protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Asxl2
Synonyms:Kiaa1685
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1922552, Asxl2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003138271 – 1370Putative Polycomb group protein ASXL2Add BLAST1370

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei150PhosphoserineBy similarity1
Modified residuei477PhosphoserineBy similarity1
Modified residuei524PhosphoserineBy similarity1
Modified residuei553PhosphoserineBy similarity1
Modified residuei590PhosphoserineBy similarity1
Modified residuei594Asymmetric dimethylarginineCombined sources1
Modified residuei601PhosphoserineBy similarity1
Modified residuei1121PhosphoserineCombined sources1
Modified residuei1254PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BZ32

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8BZ32

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BZ32

PRoteomics IDEntifications database

More...
PRIDEi
Q8BZ32

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
265120

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BZ32

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BZ32

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PPARA and PPARG.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
217375, 4 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000106846

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BZ32, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BZ32

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 86HTH HARE-typePROSITE-ProRule annotationAdd BLAST76
Domaini229 – 338DEUBADPROSITE-ProRule annotationAdd BLAST110

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni92 – 216DisorderedSequence analysisAdd BLAST125
Regioni340 – 487DisorderedSequence analysisAdd BLAST148
Regioni516 – 535DisorderedSequence analysisAdd BLAST20
Regioni643 – 734DisorderedSequence analysisAdd BLAST92
Regioni805 – 891DisorderedSequence analysisAdd BLAST87
Regioni1103 – 1175DisorderedSequence analysisAdd BLAST73

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi178 – 182Nuclear localization signalSequence analysis5
Motifi258 – 262LXXLL motif5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi92 – 106Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi107 – 121Polar residuesSequence analysisAdd BLAST15
Compositional biasi153 – 167Polar residuesSequence analysisAdd BLAST15
Compositional biasi176 – 202Polar residuesSequence analysisAdd BLAST27
Compositional biasi340 – 357Polar residuesSequence analysisAdd BLAST18
Compositional biasi415 – 429Polar residuesSequence analysisAdd BLAST15
Compositional biasi448 – 462Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi463 – 484Polar residuesSequence analysisAdd BLAST22
Compositional biasi520 – 535Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi705 – 734Polar residuesSequence analysisAdd BLAST30
Compositional biasi826 – 891Polar residuesSequence analysisAdd BLAST66
Compositional biasi1148 – 1175Polar residuesSequence analysisAdd BLAST28

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Asx family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1332 – 1369PHD-type; atypicalAdd BLAST38

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QWPH, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BZ32

Database of Orthologous Groups

More...
OrthoDBi
123355at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026905, ASX-like_PHD
IPR024811, ASX/ASX-like
IPR028020, ASX_DEUBAD_dom
IPR024817, ASXL2
IPR007759, Asxl_HARE-HTH
IPR044867, DEUBAD_dom

The PANTHER Classification System

More...
PANTHERi
PTHR13578, PTHR13578, 2 hits
PTHR13578:SF11, PTHR13578:SF11, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13919, ASXH, 1 hit
PF05066, HARE-HTH, 1 hit
PF13922, PHD_3, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51916, DEUBAD, 1 hit
PS51913, HTH_HARE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q8BZ32-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MREKGRRKKG RTWAEAAKTV LEKYPNTPMS HKEILQVIQR EGLKEIRSGT
60 70 80 90 100
SPLACLNAML HTNSRGEEGI FYKVPGRMGV YTLKKDVPDG VKELSECSEE
110 120 130 140 150
SSDGQSDSHS SDNSSSSDGG SNKEGRKSRW KRKVSSRLSH PPSPPSGCPS
160 170 180 190 200
PTIPASKVIS PSQKHSKKAL KQALKQQQQK KKQQQCRPSM SISNQHLSLK
210 220 230 240 250
TVKAASDSVP AKPGQMKRTK CADIDVETPD SILVNTNLRA LINKHTFSVL
260 270 280 290 300
PGDCQQRLLL LLPEVDRQVG PDGLMKLNGS ALNNEFFTSA AQGWKERLSE
310 320 330 340 350
GEFTPEMQVR IRQEIEKEKK VELWKEQFFE NYYGQSSGLS LEDSQKLTAS
360 370 380 390 400
SSDPKAKKTP AEQPKSILPS EASPVRIVPV VPQSECKEEA VQIPSPSQKE
410 420 430 440 450
ENQDEARPDS KSPEPVLASA SNTNELITMK PIKSPKDEGL LEQKPVACAE
460 470 480 490 500
QESEKENHVT TTSRNNKSEN QEALAISPSK SKNAGLQKPI IKPVAEASPL
510 520 530 540 550
NPDMKMPPAT VTDQIQESLK RKSSLTDEEA TSSWEKRPRI TENRQHQQPF
560 570 580 590 600
QVSPQPFLNR GDRVQVRKVP PLKIPVSRIS PMLFSTSQVS PRARFPISIT
610 620 630 640 650
SPYRTGARTL ADIKAKAQLV EAQKAAAAAA AAAAAAASVG GTIPGPGPGG
660 670 680 690 700
GQSPREGGER KIAGGGSAGS DPVSTNGKGP TLELAGTGSR GGTRELLPCG
710 720 730 740 750
PQPETNMPGQ AQPPGISGAQ LQQTSSVPTG LASSGACTSV PLPAHIEISN
760 770 780 790 800
SEKPNLHKAT ATAASPCHLQ DPRSCRLEKA LSPTGPPLIS GASTVYFVAD
810 820 830 840 850
GTVEPKAGSN KNAPKPSALA KTTAPAPLDM TSSPVTTASL EKLPVPQISG
860 870 880 890 900
TATSTGSAPS SSTLPAASSL KTPGTSANMN GPISRTSSSI PANNPLVTQL
910 920 930 940 950
LQGKDVPLEQ ILPKPLTKIE MKTVPLTTKE EKGIGIFPGI SVMESSSREE
960 970 980 990 1000
VNGRQAHLAI PQLGKPLQSK QLSQVPRPVF TAKDRKDPCI DTHQYREGLS
1010 1020 1030 1040 1050
KTTQDQLFQT LIQRAQRQSV LSFVPPSQFN FAHSGFHLED ISTSQKFMLG
1060 1070 1080 1090 1100
FAGRRTSKPA MAGHYLLNIS TYGRGTENIK RTHSVNPDDR FCLSSPTEAL
1110 1120 1130 1140 1150
RMGHADYKNT TGEISSKEDE SDEDRVGDEQ EPISVKEEPW ASQSSGRHPH
1160 1170 1180 1190 1200
HGEASSTNDC LASKNGKTEA PVSEQTTLGQ ENYIFSRGQA SDEKSLPRDF
1210 1220 1230 1240 1250
IPAAHKQMTH AVRGKTVCSS PELFNSTALS LPADSPTHQP LLLPPLQTPK
1260 1270 1280 1290 1300
LYGSPTQIGP SYRGMINVST SSDMDHNSAI PGSQVSSNVG DVMSFSVTVT
1310 1320 1330 1340 1350
TIPASQAMNP SSHGQTIPVQ TFPDDNSIED TPSKCYCRLK AMIMCKGCGA
1360 1370
FCHDDCIGPS KLCVSCLVVR
Length:1,370
Mass (Da):147,107
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5E93DCF61F64861B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6WV21F6WV21_MOUSE
Putative Polycomb group protein ASX...
Asxl2
1,370Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6REV1D6REV1_MOUSE
Putative Polycomb group protein ASX...
Asxl2
1,370Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z112D3Z112_MOUSE
Putative Polycomb group protein ASX...
Asxl2
597Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RI62D6RI62_MOUSE
Putative Polycomb group protein ASX...
Asxl2
403Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UXC9G3UXC9_MOUSE
Putative Polycomb group protein ASX...
Asxl2
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti564V → S in BAE36927 (PubMed:16141072).Curated1
Sequence conflicti621E → K in BAE36927 (PubMed:16141072).Curated1
Sequence conflicti621E → K in BAC65822 (PubMed:12693553).Curated1
Sequence conflicti627A → P in BAE36927 (PubMed:16141072).Curated1
Sequence conflicti646P → L in BAC65822 (PubMed:12693553).Curated1
Sequence conflicti686G → V in BAE36927 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK036839 mRNA Translation: BAC29602.1
AK162455 mRNA Translation: BAE36927.1
AK122540 mRNA Translation: BAC65822.1

NCBI Reference Sequences

More...
RefSeqi
NP_001257917.1, NM_001270988.1
NP_766009.2, NM_172421.5

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
75302

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:75302

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036839 mRNA Translation: BAC29602.1
AK162455 mRNA Translation: BAE36927.1
AK122540 mRNA Translation: BAC65822.1
RefSeqiNP_001257917.1, NM_001270988.1
NP_766009.2, NM_172421.5

3D structure databases

SMRiQ8BZ32
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi217375, 4 interactors
STRINGi10090.ENSMUSP00000106846

PTM databases

iPTMnetiQ8BZ32
PhosphoSitePlusiQ8BZ32

Proteomic databases

jPOSTiQ8BZ32
MaxQBiQ8BZ32
PaxDbiQ8BZ32
PRIDEiQ8BZ32
ProteomicsDBi265120

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
75302

Genome annotation databases

GeneIDi75302
KEGGimmu:75302

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55252
MGIiMGI:1922552, Asxl2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiENOG502QWPH, Eukaryota
InParanoidiQ8BZ32
OrthoDBi123355at2759

Enzyme and pathway databases

ReactomeiR-MMU-5689603, UCH proteinases

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
75302, 10 hits in 63 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Asxl2, mouse

Protein Ontology

More...
PROi
PR:Q8BZ32
RNActiQ8BZ32, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR026905, ASX-like_PHD
IPR024811, ASX/ASX-like
IPR028020, ASX_DEUBAD_dom
IPR024817, ASXL2
IPR007759, Asxl_HARE-HTH
IPR044867, DEUBAD_dom
PANTHERiPTHR13578, PTHR13578, 2 hits
PTHR13578:SF11, PTHR13578:SF11, 2 hits
PfamiView protein in Pfam
PF13919, ASXH, 1 hit
PF05066, HARE-HTH, 1 hit
PF13922, PHD_3, 1 hit
PROSITEiView protein in PROSITE
PS51916, DEUBAD, 1 hit
PS51913, HTH_HARE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiASXL2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BZ32
Secondary accession number(s): Q3TRU9, Q80TA5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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