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Entry version 129 (18 Sep 2019)
Sequence version 2 (16 Aug 2005)
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Protein

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

Gene

Arap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri698 – 721C4-typePROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-194840 Rho GTPase cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
Alternative name(s):
Centaurin-delta-1
Short name:
Cnt-d1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Arap2
Synonyms:Centd1, Gm148, Kiaa0580
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2684416 Arap2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000742131 – 1703Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2Add BLAST1703

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei77PhosphotyrosineCombined sources1
Modified residuei1627PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BZ05

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BZ05

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BZ05

PRoteomics IDEntifications database

More...
PRIDEi
Q8BZ05

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BZ05

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BZ05

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000075924

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BZ05

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 70SAMPROSITE-ProRule annotationAdd BLAST65
Domaini480 – 572PH 1PROSITE-ProRule annotationAdd BLAST93
Domaini585 – 677PH 2PROSITE-ProRule annotationAdd BLAST93
Domaini674 – 809Arf-GAPPROSITE-ProRule annotationAdd BLAST136
Domaini899 – 1001PH 3PROSITE-ProRule annotationAdd BLAST103
Domaini1012 – 1110PH 4PROSITE-ProRule annotationAdd BLAST99
Domaini1114 – 1295Rho-GAPPROSITE-ProRule annotationAdd BLAST182
Domaini1324 – 1418Ras-associatingPROSITE-ProRule annotationAdd BLAST95
Domaini1428 – 1531PH 5PROSITE-ProRule annotationAdd BLAST104

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri698 – 721C4-typePROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1117 Eukaryota
COG5347 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000246988

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BZ05

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BZ05

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04385 RhoGAP_ARAP, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.50, 1 hit
1.10.555.10, 1 hit
2.30.29.30, 5 hits
3.30.40.160, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000159 RA_dom
IPR008936 Rho_GTPase_activation_prot
IPR037858 RhoGAP_ARAP
IPR000198 RhoGAP_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 4 hits
PF00788 RA, 1 hit
PF00620 RhoGAP, 1 hit
PF00536 SAM_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00405 REVINTRACTNG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 5 hits
SM00324 RhoGAP, 1 hit
SM00454 SAM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47769 SSF47769, 1 hit
SSF48350 SSF48350, 1 hit
SSF57863 SSF57863, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 4 hits
PS50200 RA, 1 hit
PS50238 RHOGAP, 1 hit
PS50105 SAM_DOMAIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BZ05-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSVSEVNAD IRDFLMSINL EQYLLHFREF GFYTVRDCTS INDSVLHQIG
60 70 80 90 100
ISPTGHRRRI LKQLQMIFSK MQDFPIYANV HKAKNGSTTK EQQHSDPSSS
110 120 130 140 150
THTGIECSDS ITVHRPGPAP SEMVTTSTLS EGNCQSPKSH DKLCLSSHDL
160 170 180 190 200
LCPEEELHQN VDSSKDSLFG GVNVKIDPLI TKRAVEYTAG EEHTEKGNLT
210 220 230 240 250
SEDSSKALST NTECLPSGDC PTSGTHSGNG TNGVLESFPP TPFFQFQGEM
260 270 280 290 300
VVNELYVPSS PVHGPMRSRS KLVSRPSRSF LLRHRPVPEI PGSTKSIPGS
310 320 330 340 350
YFRDRRSNTT SAGKSLTLKN SNEDNSTSIF PYGETFLFQR LESSKKRSIK
360 370 380 390 400
NEFWPHENTV KEEAATTRNS ILTQSSIYDN RKEKVSEDKV EDIWIPREDK
410 420 430 440 450
NNLAQDSASE SEYSTVEECF QSLRRKNSKA SKSRTQKAFY LDPFNRHSYP
460 470 480 490 500
LSSTSGNTEP SSTISNAISP YACFYGSSAA KEKCGWLDKL SPQGKRMFQK
510 520 530 540 550
RWVKFDGLSI SHYNNDREMY SKGIIPLTAI STVRAQGDNK FEIVTTQRTF
560 570 580 590 600
VFRVEKEEER NDWISILLSA LKSPSLASQL QAAVAPEKCG YLELRGYKAK
610 620 630 640 650
IFTVLRGNSV WLCKNEQDFK SGLGITIIPM NVANVKQVDR AVKQSFEIIT
660 670 680 690 700
PYRSFSFTAD SEREKQEWIE AVQQSIAETL SDYEVAEKIW FNESNRSCAD
710 720 730 740 750
CKAPDPDWAS INLCVVICKK CAGQHRSLGP KDCKVRSLKM DASIWSNELI
760 770 780 790 800
ELFIVIGNKR ANDFWAGNLQ KDEELQVDSP VEKRKNFITQ KYKEGKFRKT
810 820 830 840 850
LLASLTKEEL NKALCAAVVK PDVLETMALL FSGADVMCAT GDPVHSTPYL
860 870 880 890 900
LAKKAGQSLQ MEFLYHNKFS DFPQYDAHFE GGSSQDAAQS SFLCDFLYQT
910 920 930 940 950
AAAASRVSSE KKLLEDTNKK WCVLEGGFLS YYENDRCTTP NGTINISEVI
960 970 980 990 1000
CLAVHKEDFY LNTGPIFVFE IYLPSERVFL FGAETSQIQR KWTETIAKRF
1010 1020 1030 1040 1050
VPFVAENLTE ADYDLIGQLF YKDCHALDQW RKGWFAMDKS SLCFCLQTQE
1060 1070 1080 1090 1100
AQEERMNLRR LQELTISTMV QNGEKVDVLL LVEKGRTLYI HGHTKLDFTV
1110 1120 1130 1140 1150
WHTAIEKAAG TDGNALQDQQ LCKNDVPIIV NSCIAFVTQY GLGCKYIYQK
1160 1170 1180 1190 1200
DGDPLHISEL LESFKKDARS VKLRAGKHQL EDVTGVLKSF LSDIDDALLT
1210 1220 1230 1240 1250
KELYPYWVSA LDTQDEKERT SKYRAFIRSL PGVNRATLAA LIEHLYRVQK
1260 1270 1280 1290 1300
CSEINHMNAH NLAMVFSSCL FQTKGQTSEE VNVIEDLINN YVEIFEVKED
1310 1320 1330 1340 1350
QVKQMDIENS FITKWKDTQV SQAGDLLIEV FVERKEPDCS IIIRISPVME
1360 1370 1380 1390 1400
AEELTNDILA IKNIIPMKGD IWATFEVIEN EELERPLHYT ENVLEQVLQW
1410 1420 1430 1440 1450
SSLAEPGSAY LVVKRFLTVD SIKQCREKSI KEGILKLKEE PSKILSGNKF
1460 1470 1480 1490 1500
QDRCVVLRDG HLFIYKDPKS SKHDKMFPLR AMKFYLGVKK KMKPPTSWGL
1510 1520 1530 1540 1550
TVYSEKHHWH LCCDSLQAQM EWMASIFIAQ HENDIWPPAG KERKRSITKN
1560 1570 1580 1590 1600
PKIGGLPLIP IQHERNATQA RKNIETARAE LERLRLSEKH DPRDFTDSSL
1610 1620 1630 1640 1650
KDRASLIAHC LEHKDEKLRN RARKHRSFNC LEDTEAEGPH GLPKAYKGPK
1660 1670 1680 1690 1700
TLKKTEERNS KATLDADPKL PSKVIEELSV VLQRSRPLHK ELPDEQTLQK

EVK
Length:1,703
Mass (Da):193,398
Last modified:August 16, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D99E59D35E0ABEB
GO
Isoform 2 (identifier: Q8BZ05-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1519: Missing.
     1531-1575: Missing.

Note: No experimental confirmation available.
Show »
Length:139
Mass (Da):16,063
Checksum:iBD062C4BFD0425F4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QP44E9QP44_MOUSE
Arf-GAP with Rho-GAP domain, ANK re...
Arap2
1,703Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CXD0E0CXD0_MOUSE
Arf-GAP with Rho-GAP domain, ANK re...
Arap2
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0149961 – 1519Missing in isoform 2. 1 PublicationAdd BLAST1519
Alternative sequenceiVSP_0149971531 – 1575Missing in isoform 2. 1 PublicationAdd BLAST45

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK037027 mRNA Translation: BAC29675.1
AK084988 mRNA Translation: BAC39331.1
AK122316 mRNA Translation: BAC65598.1
BC018234 mRNA Translation: AAH18234.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS51506.1 [Q8BZ05-1]

Genome annotation databases

UCSC genome browser

More...
UCSCi
uc008xlz.2 mouse [Q8BZ05-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK037027 mRNA Translation: BAC29675.1
AK084988 mRNA Translation: BAC39331.1
AK122316 mRNA Translation: BAC65598.1
BC018234 mRNA Translation: AAH18234.1
CCDSiCCDS51506.1 [Q8BZ05-1]

3D structure databases

SMRiQ8BZ05
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075924

PTM databases

iPTMnetiQ8BZ05
PhosphoSitePlusiQ8BZ05

Proteomic databases

EPDiQ8BZ05
jPOSTiQ8BZ05
PaxDbiQ8BZ05
PRIDEiQ8BZ05

Genome annotation databases

UCSCiuc008xlz.2 mouse [Q8BZ05-2]

Organism-specific databases

MGIiMGI:2684416 Arap2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1117 Eukaryota
COG5347 LUCA
HOGENOMiHOG000246988
InParanoidiQ8BZ05
PhylomeDBiQ8BZ05

Enzyme and pathway databases

ReactomeiR-MMU-194840 Rho GTPase cycle

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Arap2 mouse

Protein Ontology

More...
PROi
PR:Q8BZ05

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

CDDicd04385 RhoGAP_ARAP, 1 hit
Gene3Di1.10.150.50, 1 hit
1.10.555.10, 1 hit
2.30.29.30, 5 hits
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000159 RA_dom
IPR008936 Rho_GTPase_activation_prot
IPR037858 RhoGAP_ARAP
IPR000198 RhoGAP_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 4 hits
PF00788 RA, 1 hit
PF00620 RhoGAP, 1 hit
PF00536 SAM_1, 1 hit
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 5 hits
SM00324 RhoGAP, 1 hit
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
SSF48350 SSF48350, 1 hit
SSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 4 hits
PS50200 RA, 1 hit
PS50238 RHOGAP, 1 hit
PS50105 SAM_DOMAIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARAP2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BZ05
Secondary accession number(s): Q80TX2, Q8C3T2, Q8VEL6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: August 16, 2005
Last modified: September 18, 2019
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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