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Entry version 131 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Tetratricopeptide repeat protein 39B

Gene

Ttc39b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid metabolism, Ubl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetratricopeptide repeat protein 39B
Short name:
TPR repeat protein 39B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ttc39bImported
Synonyms:T391 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917113, Ttc39b

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Chow-fed deficient mice display increased HDL-cholesterol level, accompanied by increased ABCA1 and MYLIP expression, increased oxysterols receptors LXR (NR1H3 AND NR1H2) protein level without change in NR1H2/3 mRNA levels. Many NR1H2/3 targets are up-regulated, including ABCG5/8, SCD1, ELOVL5, INSIG2 and LPCAT3. Deficiency of TTC39B reduced processing of SREBP1 a pivotal regulator of lipogenesis. When fed with a high-fat/high-cholesterol/bile-salt diet during 20 weeks, used as a model of steatohepatitis resembling human non-alcoholic steatohepatitis, mice show increased HDL cholesterol and APOA1 levels, reduced VLDL (very low density lipoprotein), and reduced mortality compared with wild-type. The livers of deficient mice shown diminished hepatic triglyceride and cholesteryl ester accumulation, fewer inflammatory foci consisting of neutrophils and lymphocytes, less hepatocellular ballooning degeneration and less hepatocyte proliferation compared to control. Knockout mice lacking both TTC39B and LDLR, fed a Western diet for 20 weeks, exhibit a reduction in LDL-cholesterol, but plasma triglyceride levels are not different. Atherosclerotic lesion area of the aorta are reduced compared to LDLR single knockout mice.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002920021 – 617Tetratricopeptide repeat protein 39BAdd BLAST617

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BYY4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BYY4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BYY4

PeptideAtlas

More...
PeptideAtlasi
Q8BYY4

PRoteomics IDEntifications database

More...
PRIDEi
Q8BYY4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BYY4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BYY4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

High expression in lung and spleen. Low lower expression in liver and small intestine. Weak expression in heart, brain, kidney, adipose, and adrenal gland.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000038172, Expressed in cardiac ventricle and 249 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BYY4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BYY4, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
213723, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000099887

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BYY4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati328 – 361TPR 1Add BLAST34
Repeati520 – 553TPR 2Add BLAST34
Repeati561 – 594TPR 3Add BLAST34

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TTC39 family.Curated

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3783, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182917

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010086_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BYY4

Identification of Orthologs from Complete Genome Data

More...
OMAi
ELMYVWN

Database of Orthologous Groups

More...
OrthoDBi
754120at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BYY4

TreeFam database of animal gene trees

More...
TreeFami
TF313761

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019412, Iml2/TPR_39
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR034305, TTC39B

The PANTHER Classification System

More...
PANTHERi
PTHR31859, PTHR31859, 1 hit
PTHR31859:SF4, PTHR31859:SF4, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10300, DUF3808, 1 hit
PF13174, TPR_6, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BYY4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALVGSRVEL DADEDIFEDA LETISRSPSD MATSGFHFVP CETKRTSRQL
60 70 80 90 100
GASAMGRPEG SSAKVDLKSG LEECAEALNL FLSNKFKDAL ELLRPWAKES
110 120 130 140 150
MYHALGYSTI VVLQAVMTFE QQDIQNGISA MKDALQTCQK YRKKCTVVES
160 170 180 190 200
FSSLLSRGSL EQLSEEEMHA EICYAECLLQ KAALTFVQDE NMINFIKGGL
210 220 230 240 250
KIRTSYQIYK ECLSILHVIQ KNKQEQHFFY EFEGGVKLGT GAFNLMLSLL
260 270 280 290 300
PARIIRLLEF IGFSGNRDLG LLQLREGASG SSMRSPLCCL TILAFHTYIS
310 320 330 340 350
LILGTGEVNV VEAESLLAPF LQQFPNGSLI LFYHARIELL KGNTEKAQET
360 370 380 390 400
FRKCISVQEE WKQFHHLCYW ELMWIHIYQQ NWMQAYYYSD LLCKESKWSK
410 420 430 440 450
ATYVFLKAAI LSMLPEEEVA ATKENVVSLF RQVDGLKQRI AGKSLPTEKF
460 470 480 490 500
AVRKARRYSP PSGVPGKLVM PALEMMYVWN GFSIVGKRKD LSENLLVTVE
510 520 530 540 550
KAEEALQNQD FTDYSVDDEC LVKLLKGCCL KNLERPLQAE LCFNHVVESE
560 570 580 590 600
KLLKYDHYLV PFTLFELAFL YKSQGEIDKA IKVLETARNN YKDYSLESRL
610
HFRIQAALHL WKKPSTD
Length:617
Mass (Da):70,293
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD7FF38C238C6A5BB
GO
Isoform 2 (identifier: Q8BYY4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     474-518: EMMYVWNGFS...QDFTDYSVDD → VLLLLTVYLP...YYVFLYLYVN
     519-617: Missing.

Show »
Length:518
Mass (Da):58,620
Checksum:i8EF03B3F6FEF19DD
GO
Isoform 3 (identifier: Q8BYY4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     167-209: EMHAEICYAE...LKIRTSYQIY → TDLRASLRTR...HCLFLPGNPM
     210-617: Missing.

Show »
Length:209
Mass (Da):23,306
Checksum:i7A6FA41165EE6CB0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E0CX38E0CX38_MOUSE
Tetratricopeptide repeat protein 39...
Ttc39b
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CY48E0CY48_MOUSE
Tetratricopeptide repeat protein 39...
Ttc39b
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026359167 – 209EMHAE…SYQIY → TDLRASLRTRAGTGRPKVFP RQSMRLNWPQYDLHCLFLPG NPM in isoform 3. 1 PublicationAdd BLAST43
Alternative sequenceiVSP_026360210 – 617Missing in isoform 3. 1 PublicationAdd BLAST408
Alternative sequenceiVSP_026361474 – 518EMMYV…YSVDD → VLLLLTVYLPEIRSLLGASR DALTFACEVYSSVENYYVFL YLYVN in isoform 2. 1 PublicationAdd BLAST45
Alternative sequenceiVSP_026362519 – 617Missing in isoform 2. 1 PublicationAdd BLAST99

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK007856 mRNA Translation: BAB25308.1
AK037208 mRNA Translation: BAC29754.1
AK049108 mRNA Translation: BAC33545.1
AK132655 mRNA Translation: BAE21284.1
BX571885 Genomic DNA No translation available.
CH466527 Genomic DNA Translation: EDL31029.1
BC151021 mRNA Translation: AAI51022.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18297.1 [Q8BYY4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_081514.1, NM_027238.2 [Q8BYY4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030205; ENSMUSP00000030205; ENSMUSG00000038172 [Q8BYY4-3]
ENSMUST00000048274; ENSMUSP00000040590; ENSMUSG00000038172 [Q8BYY4-2]
ENSMUST00000102823; ENSMUSP00000099887; ENSMUSG00000038172 [Q8BYY4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
69863

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:69863

UCSC genome browser

More...
UCSCi
uc008tkq.1, mouse [Q8BYY4-1]
uc008tkr.1, mouse [Q8BYY4-2]
uc008tks.1, mouse [Q8BYY4-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007856 mRNA Translation: BAB25308.1
AK037208 mRNA Translation: BAC29754.1
AK049108 mRNA Translation: BAC33545.1
AK132655 mRNA Translation: BAE21284.1
BX571885 Genomic DNA No translation available.
CH466527 Genomic DNA Translation: EDL31029.1
BC151021 mRNA Translation: AAI51022.1
CCDSiCCDS18297.1 [Q8BYY4-1]
RefSeqiNP_081514.1, NM_027238.2 [Q8BYY4-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi213723, 1 interactor
STRINGi10090.ENSMUSP00000099887

PTM databases

iPTMnetiQ8BYY4
PhosphoSitePlusiQ8BYY4

Proteomic databases

EPDiQ8BYY4
jPOSTiQ8BYY4
PaxDbiQ8BYY4
PeptideAtlasiQ8BYY4
PRIDEiQ8BYY4

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
24508, 95 antibodies

Genome annotation databases

EnsembliENSMUST00000030205; ENSMUSP00000030205; ENSMUSG00000038172 [Q8BYY4-3]
ENSMUST00000048274; ENSMUSP00000040590; ENSMUSG00000038172 [Q8BYY4-2]
ENSMUST00000102823; ENSMUSP00000099887; ENSMUSG00000038172 [Q8BYY4-1]
GeneIDi69863
KEGGimmu:69863
UCSCiuc008tkq.1, mouse [Q8BYY4-1]
uc008tkr.1, mouse [Q8BYY4-2]
uc008tks.1, mouse [Q8BYY4-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
158219
MGIiMGI:1917113, Ttc39b

Phylogenomic databases

eggNOGiKOG3783, Eukaryota
GeneTreeiENSGT00950000182917
HOGENOMiCLU_010086_3_0_1
InParanoidiQ8BYY4
OMAiELMYVWN
OrthoDBi754120at2759
PhylomeDBiQ8BYY4
TreeFamiTF313761

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
69863, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ttc39b, mouse

Protein Ontology

More...
PROi
PR:Q8BYY4
RNActiQ8BYY4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000038172, Expressed in cardiac ventricle and 249 other tissues
ExpressionAtlasiQ8BYY4, baseline and differential
GenevisibleiQ8BYY4, MM

Family and domain databases

InterProiView protein in InterPro
IPR019412, Iml2/TPR_39
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
IPR034305, TTC39B
PANTHERiPTHR31859, PTHR31859, 1 hit
PTHR31859:SF4, PTHR31859:SF4, 1 hit
PfamiView protein in Pfam
PF10300, DUF3808, 1 hit
PF13174, TPR_6, 1 hit
SUPFAMiSSF48452, SSF48452, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTT39B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BYY4
Secondary accession number(s): B2RX73
, Q3V168, Q8BX40, Q9D8N8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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