UniProtKB - Q8BYG9 (EPHAA_MOUSE)

BLAST

>sp|Q8BYG9|EPHAA_MOUSE Ephrin type-A receptor 10 OS=Mus musculus OX=10090 GN=Epha10 PE=2 SV=2
METGAGPHPLRLFVCLIPLCLALLLGPGRPGTAEEVILLDSKASQAELGWTALPSTGWEE
ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGATG
TCKETFNAYYLETETDLGRGRPRLGGNRPRKIDTIAADESFTQGDLGERKMKLNTEVREI
GPLSRQGFHLAFQDVGACVALVSVRVYYKQCRATVRGLAAFPATAAESAFSTLVEVAGTC
VAHSEGEPSSPPRMHCGADGEWLVPVGRCSCSAGFQEHGDICEACPPGFYKVSPRRPLCS
PCPEHSLALENASTFCVCQDTYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLALRLRWL
PPADSGGRSDVTYSLLCLRCGRDGPAGACQPCGPRVAFVPRQAGLRERAATLLHLRPGAR
YTVRVAALNGVSGPAAAAGATYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPVPA
GAPGTNSTEYEIRYYEKGQSEQTYSTVKTGAPAVTVTNLKPATRYVFQIRAASPGPLWEA
QSFSPSIEVQTPGEVAPGSRDQSPAVVVTVVTISALLVLGSVMSVLAIWRRPCDGKGSGN
AHDEEELYFHFKVPTRRTFLDPQSCGDPLQAVHLFAKELDAKSVTLEKSLGAGRFGTLCC
GCLQLPGRQELPVAVHTLRDGCSDSQRLSFLAEALTLGQFDHSHIVRLEGVVTRGNPLMI
VTEYMNLGALDDFLRHHEGELVAAQLMGLLPGLASAMKYLSEMGYVHRGLAARRVLVSSG
LLCKISGFGRGPRDRAEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIVMWEVMA
FGERPYWDMSGQDVIKAVEDGFRLPPPRNCPSQLHRLMLECWQKDPSERPRFSQIHSILS
KMGQEPEPSKCASTTCLRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDNFSAAGYGS
LEAVAEMTAQDLGSLGISSTEHRESLLSGISALQTRVLQLQGQGVQV

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History
Entry version 130 (07 Nov 2018)
Sequence version 2 (20 Mar 2007)
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Protein

Ephrin type-A receptor 10

Gene

Epha10

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at transcript levelⁱ

Functionⁱ

Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5 (By similarity).By similarity

Catalytic activityⁱ

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
transmembrane-ephrin receptor activity Source: MGI
transmembrane receptor protein tyrosine kinase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
transmembrane signaling receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell differentiation
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
negative regulation of apoptotic process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
negative regulation of signal transduction
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of ERK1 and ERK2 cascade
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Kinase, Receptor, Transferase, Tyrosine-protein kinase
Ligand	ATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2682334 EPH-Ephrin signaling R-MMU-3928663 EPHA-mediated growth cone collapse R-MMU-3928665 EPH-ephrin mediated repulsion of cells

Reactomeⁱ

R-MMU-2682334 EPH-Ephrin signaling
R-MMU-3928663 EPHA-mediated growth cone collapse
R-MMU-3928665 EPH-ephrin mediated repulsion of cells

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ephrin type-A receptor 10 (EC:2.7.10.1)
Gene namesⁱ	Name:Epha10
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 4

Organism-specific databases

MGIⁱ	MGI:3586824 Epha10

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	23 – 565	ExtracellularSequence analysisAdd BLAST	543
Transmembraneⁱ	566 – 586	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	587 – 1007	CytoplasmicSequence analysisAdd BLAST	421

Keywords - Cellular componentⁱ

Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 22	Sequence analysisAdd BLAST		22
ChainⁱPRO_0000280444	23 – 1007	Ephrin type-A receptor 10Add BLAST		985

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Glycosylationⁱ	311	N-linked (GlcNAc...) asparagineSequence analysis		1
Glycosylationⁱ	486	N-linked (GlcNAc...) asparagineSequence analysis		1

Keywords - PTMⁱ

Glycoprotein

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q8BYG9
PRIDEⁱ	Q8BYG9

PTM databases

iPTMnetⁱ	Q8BYG9
PhosphoSitePlusⁱ	Q8BYG9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000028876 Expressed in 94 organ(s), highest expression level in bone marrow
CleanExⁱ	MM_EPHA10
ExpressionAtlasⁱ	Q8BYG9 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8BYG9
SMRⁱ	Q8BYG9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	35 – 216	Eph LBDPROSITE-ProRule annotationAdd BLAST	182
Domainⁱ	340 – 452	Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST	113
Domainⁱ	456 – 554	Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST	99
Domainⁱ	644 – 899	Protein kinasePROSITE-ProRule annotationAdd BLAST	256
Domainⁱ	932 – 996	SAMPROSITE-ProRule annotationAdd BLAST	65

Domainⁱ

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesⁱ

Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.PROSITE-ProRule annotation

Keywords - Domainⁱ

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150909
HOGENOMⁱ	HOG000233856
HOVERGENⁱ	HBG062180
InParanoidⁱ	Q8BYG9
KEGG Orthology (KO) More...KOⁱ	K08897
PhylomeDBⁱ	Q8BYG9

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00063 FN3, 2 hits
Gene3Dⁱ	2.60.120.260, 1 hit 2.60.40.10, 2 hits
InterProⁱ	View protein in InterPro IPR027936 Eph_TM IPR001090 Ephrin_rcpt_lig-bd_dom IPR003961 FN3_dom IPR036116 FN3_sf IPR008979 Galactose-bd-like_sf IPR013783 Ig-like_fold IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR001660 SAM IPR013761 SAM/pointed_sf IPR001245 Ser-Thr/Tyr_kinase_cat_dom IPR011641 Tyr-kin_ephrin_A/B_rcpt-like IPR016257 Tyr_kinase_ephrin_rcpt IPR001426 Tyr_kinase_rcpt_V_CS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14575 EphA2_TM, 1 hit PF01404 Ephrin_lbd, 1 hit PF00041 fn3, 2 hits PF07714 Pkinase_Tyr, 1 hit PF07647 SAM_2, 1 hit
PIRSFⁱ	PIRSF000666 TyrPK_ephrin_receptor, 1 hit
PRINTSⁱ	PR00109 TYRKINASE
SMARTⁱ	View protein in SMART SM00615 EPH_lbd, 1 hit SM01411 Ephrin_rec_like, 1 hit SM00060 FN3, 2 hits SM00454 SAM, 1 hit
SUPFAMⁱ	SSF47769 SSF47769, 1 hit SSF49265 SSF49265, 1 hit SSF49785 SSF49785, 1 hit SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS01186 EGF_2, 1 hit PS51550 EPH_LBD, 1 hit PS50853 FN3, 2 hits PS50011 PROTEIN_KINASE_DOM, 1 hit PS00790 RECEPTOR_TYR_KIN_V_1, 1 hit PS00791 RECEPTOR_TYR_KIN_V_2, 1 hit PS50105 SAM_DOMAIN, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show all Align All

Isoform 1 (identifier: Q8BYG9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
METGAGPHPL RLFVCLIPLC LALLLGPGRP GTAEEVILLD SKASQAELGW 
        60         70         80         90        100
TALPSTGWEE ISGVDEHDRP IRTYQVCNVL EPNQDNWLQT GWISRGRGQR 
       110        120        130        140        150
IFVELQFTLR DCSSIPGATG TCKETFNAYY LETETDLGRG RPRLGGNRPR 
       160        170        180        190        200
KIDTIAADES FTQGDLGERK MKLNTEVREI GPLSRQGFHL AFQDVGACVA 
       210        220        230        240        250
LVSVRVYYKQ CRATVRGLAA FPATAAESAF STLVEVAGTC VAHSEGEPSS 
       260        270        280        290        300
PPRMHCGADG EWLVPVGRCS CSAGFQEHGD ICEACPPGFY KVSPRRPLCS 
       310        320        330        340        350
PCPEHSLALE NASTFCVCQD TYARSPTDPP SASCTRPPSA PRDLQYSLSR 
       360        370        380        390        400
SPLALRLRWL PPADSGGRSD VTYSLLCLRC GRDGPAGACQ PCGPRVAFVP 
       410        420        430        440        450
RQAGLRERAA TLLHLRPGAR YTVRVAALNG VSGPAAAAGA TYAQVTVSTG 
       460        470        480        490        500
PGAPWEEDEI RRDRVEPQSV SLSWREPVPA GAPGTNSTEY EIRYYEKGQS 
       510        520        530        540        550
EQTYSTVKTG APAVTVTNLK PATRYVFQIR AASPGPLWEA QSFSPSIEVQ 
       560        570        580        590        600
TPGEVAPGSR DQSPAVVVTV VTISALLVLG SVMSVLAIWR RPCDGKGSGN 
       610        620        630        640        650
AHDEEELYFH FKVPTRRTFL DPQSCGDPLQ AVHLFAKELD AKSVTLEKSL 
       660        670        680        690        700
GAGRFGTLCC GCLQLPGRQE LPVAVHTLRD GCSDSQRLSF LAEALTLGQF 
       710        720        730        740        750
DHSHIVRLEG VVTRGNPLMI VTEYMNLGAL DDFLRHHEGE LVAAQLMGLL 
       760        770        780        790        800
PGLASAMKYL SEMGYVHRGL AARRVLVSSG LLCKISGFGR GPRDRAEAVY 
       810        820        830        840        850
TTMSGRSPAL WAAPETLQFG HFSSASDVWS FGIVMWEVMA FGERPYWDMS 
       860        870        880        890        900
GQDVIKAVED GFRLPPPRNC PSQLHRLMLE CWQKDPSERP RFSQIHSILS 
       910        920        930        940        950
KMGQEPEPSK CASTTCLRPP TPLADRAFST FPSFGSVGAW LEALDLCRYK 
       960        970        980        990       1000
DNFSAAGYGS LEAVAEMTAQ DLGSLGISST EHRESLLSGI SALQTRVLQL 

QGQGVQV

Length:1,007

Mass (Da):109,100

Last modified:March 20, 2007 - v2

Checksum:ⁱ157A0E17CDCB9ED9

Isoform 2 (identifier: Q8BYG9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
284-292: ACPPGFYKV → GIQGPRGMG
293-1007: Missing.

« Hide

        10         20         30         40         50
METGAGPHPL RLFVCLIPLC LALLLGPGRP GTAEEVILLD SKASQAELGW 
        60         70         80         90        100
TALPSTGWEE ISGVDEHDRP IRTYQVCNVL EPNQDNWLQT GWISRGRGQR 
       110        120        130        140        150
IFVELQFTLR DCSSIPGATG TCKETFNAYY LETETDLGRG RPRLGGNRPR 
       160        170        180        190        200
KIDTIAADES FTQGDLGERK MKLNTEVREI GPLSRQGFHL AFQDVGACVA 
       210        220        230        240        250
LVSVRVYYKQ CRATVRGLAA FPATAAESAF STLVEVAGTC VAHSEGEPSS 
       260        270        280        290 
PPRMHCGADG EWLVPVGRCS CSAGFQEHGD ICEGIQGPRG MG

Show »

Length:292

Mass (Da):31,593

Checksum:ⁱ4CA95ED12646A858

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	F6WVB0	F6WVB0_MOUSE		Ephrin type-A receptor 10 Ephrin type-A receptor 10	Epha10	862	Annotation score:

Sequence cautionⁱ

The sequence CAM16104 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	156	A → S in BAC30423 (PubMed:16141072).Curated	1
Sequence conflictⁱ	657	T → D in CAM16104 (PubMed:19468303).Curated	1
Sequence conflictⁱ	980	T → A in CAM16104 (PubMed:19468303).Curated	1
Sequence conflictⁱ	985	S → A in CAM16104 (PubMed:19468303).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_023676	284 – 292	ACPPGFYKV → GIQGPRGMG in isoform 2. 2 Publications		9
Alternative sequenceⁱVSP_023677	293 – 1007	Missing in isoform 2. 2 PublicationsAdd BLAST		715

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK039700 mRNA Translation: BAC30423.1 AK143168 mRNA Translation: BAE25289.1 AL606933 Genomic DNA Translation: CAM16103.1 AL606933 Genomic DNA Translation: CAM16104.1 Sequence problems. BC116991 mRNA Translation: AAI16992.1 BC119084 mRNA Translation: AAI19085.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS18630.1 [Q8BYG9-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_808339.2, NM_177671.5 [Q8BYG9-2]
UniGeneⁱ	Mm.171490 Mm.491537

Genome annotation databases

Ensemblⁱ	ENSMUST00000059343; ENSMUSP00000050810; ENSMUSG00000028876 [Q8BYG9-2]
GeneIDⁱ	230735
KEGGⁱ	mmu:230735
UCSC genome browser More...UCSCⁱ	uc008urh.2 mouse [Q8BYG9-2] uc008uri.2 mouse [Q8BYG9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8BYG9	Ephrin type-A receptor 10		HUMAN		1008	UniRef90_Q5JZY3
Uncharacterized protein		NOMLE		1080
ephrin type-A receptor 10 isoform X1		DELLE		1017
ephrin type-A receptor 10 isoform X1		PHYCD		1017
Uncharacterized protein		PAPAN		1017
+85
Q8BYG9-2	Isoform 2 of Ephrin type-A receptor 10		HUMAN		295	UniRef90_Q5JZY3-2
Uncharacterized protein		MACFA		295
ephrin type-A receptor 10-like		Yangtze finless porpoise		295
Uncharacterized protein		MACMU		295
Ephrin type-A receptor 10		PTEAL		295
+23

Protein	Similar proteins		Species	Score	Length	Source
Q8BYG9	Ephrin type-A receptor 10		HUMAN		1008	UniRef50_Q5JZY3
Uncharacterized protein		NOMLE		1080
LOW QUALITY PROTEIN: ephrin type-A receptor 10		Florida manatee		1017
ephrin type-A receptor 10 isoform X1		PHYCD		1017
Uncharacterized protein		PAPAN		1017
+157
Q8BYG9-2	Isoform 2 of Ephrin type-A receptor 10		HUMAN		295	UniRef50_Q5JZY3-2
ephrin type-A receptor 10-like		BALAS		295
Uncharacterized protein		MACFA		295
Uncharacterized protein		MACMU		295
EPHA10 isoform 11		PANTR		295
+191

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK039700 mRNA Translation: BAC30423.1 AK143168 mRNA Translation: BAE25289.1 AL606933 Genomic DNA Translation: CAM16103.1 AL606933 Genomic DNA Translation: CAM16104.1 Sequence problems. BC116991 mRNA Translation: AAI16992.1 BC119084 mRNA Translation: AAI19085.1
CCDSⁱ	CCDS18630.1 [Q8BYG9-2]
RefSeqⁱ	NP_808339.2, NM_177671.5 [Q8BYG9-2]
UniGeneⁱ	Mm.171490 Mm.491537

3D structure databases

ProteinModelPortalⁱ	Q8BYG9
SMRⁱ	Q8BYG9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

PTM databases

iPTMnetⁱ	Q8BYG9
PhosphoSitePlusⁱ	Q8BYG9

Proteomic databases

PeptideAtlasⁱ	Q8BYG9
PRIDEⁱ	Q8BYG9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000059343; ENSMUSP00000050810; ENSMUSG00000028876 [Q8BYG9-2]
GeneIDⁱ	230735
KEGGⁱ	mmu:230735
UCSCⁱ	uc008urh.2 mouse [Q8BYG9-2] uc008uri.2 mouse [Q8BYG9-1]

Organism-specific databases

CTDⁱ	284656
MGIⁱ	MGI:3586824 Epha10

Phylogenomic databases

GeneTreeⁱ	ENSGT00930000150909
HOGENOMⁱ	HOG000233856
HOVERGENⁱ	HBG062180
InParanoidⁱ	Q8BYG9
KOⁱ	K08897
PhylomeDBⁱ	Q8BYG9

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2682334 EPH-Ephrin signaling R-MMU-3928663 EPHA-mediated growth cone collapse R-MMU-3928665 EPH-ephrin mediated repulsion of cells

Reactomeⁱ

R-MMU-2682334 EPH-Ephrin signaling
R-MMU-3928663 EPHA-mediated growth cone collapse
R-MMU-3928665 EPH-ephrin mediated repulsion of cells

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q8BYG9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000028876 Expressed in 94 organ(s), highest expression level in bone marrow
CleanExⁱ	MM_EPHA10
ExpressionAtlasⁱ	Q8BYG9 baseline and differential

Family and domain databases

CDDⁱ	cd00063 FN3, 2 hits
Gene3Dⁱ	2.60.120.260, 1 hit 2.60.40.10, 2 hits
InterProⁱ	View protein in InterPro IPR027936 Eph_TM IPR001090 Ephrin_rcpt_lig-bd_dom IPR003961 FN3_dom IPR036116 FN3_sf IPR008979 Galactose-bd-like_sf IPR013783 Ig-like_fold IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR001660 SAM IPR013761 SAM/pointed_sf IPR001245 Ser-Thr/Tyr_kinase_cat_dom IPR011641 Tyr-kin_ephrin_A/B_rcpt-like IPR016257 Tyr_kinase_ephrin_rcpt IPR001426 Tyr_kinase_rcpt_V_CS
Pfamⁱ	View protein in Pfam PF14575 EphA2_TM, 1 hit PF01404 Ephrin_lbd, 1 hit PF00041 fn3, 2 hits PF07714 Pkinase_Tyr, 1 hit PF07647 SAM_2, 1 hit
PIRSFⁱ	PIRSF000666 TyrPK_ephrin_receptor, 1 hit
PRINTSⁱ	PR00109 TYRKINASE
SMARTⁱ	View protein in SMART SM00615 EPH_lbd, 1 hit SM01411 Ephrin_rec_like, 1 hit SM00060 FN3, 2 hits SM00454 SAM, 1 hit
SUPFAMⁱ	SSF47769 SSF47769, 1 hit SSF49265 SSF49265, 1 hit SSF49785 SSF49785, 1 hit SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS01186 EGF_2, 1 hit PS51550 EPH_LBD, 1 hit PS50853 FN3, 2 hits PS50011 PROTEIN_KINASE_DOM, 1 hit PS00790 RECEPTOR_TYR_KIN_V_1, 1 hit PS00791 RECEPTOR_TYR_KIN_V_2, 1 hit PS50105 SAM_DOMAIN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EPHAA_MOUSE
Accessionⁱ	Q8BYG9Primary (citable) accession number: Q8BYG9 Secondary accession number(s): A2A7J5, Q3UPV5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
	Last sequence update:	March 20, 2007
	Last modified:	November 7, 2018
	This is version 130 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
Human and mouse protein kinases
Human and mouse protein kinases: classification and index

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UniProtKB - Q8BYG9 (EPHAA_MOUSE)

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Ephrin type-A receptor 10

Epha10

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ