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Entry version 96 (29 Sep 2021)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

Eif4enif1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Eif4enif1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

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MGIi
MGI:1921453, Eif4enif1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q8BY82

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q8BY82, MM

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 22DisorderedSequence analysisAdd BLAST22
Regioni40 – 99DisorderedSequence analysisAdd BLAST60
Regioni206 – 229DisorderedSequence analysisAdd BLAST24
Regioni341 – 360DisorderedSequence analysisAdd BLAST20
Regioni563 – 592DisorderedSequence analysisAdd BLAST30
Regioni618 – 669DisorderedSequence analysisAdd BLAST52
Regioni684 – 776DisorderedSequence analysisAdd BLAST93
Regioni882 – 927DisorderedSequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi80 – 99Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi341 – 357Polar residuesSequence analysisAdd BLAST17
Compositional biasi640 – 669Polar residuesSequence analysisAdd BLAST30
Compositional biasi684 – 709Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi710 – 752Polar residuesSequence analysisAdd BLAST43
Compositional biasi882 – 908Polar residuesSequence analysisAdd BLAST27

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR018862, eIF4E-T

The PANTHER Classification System

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PANTHERi
PTHR12269, PTHR12269, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF10477, EIF4E-T, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8BY82-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKSVAETEN GDAFLELKKL PTSKSPHRYT KEELLDIKER PYSKQRPSCL
60 70 80 90 100
SEKYDSDGVW DPEKWHASLY PASGRSSPVE SLKKESESDR PSLVRRIADP
110 120 130 140 150
RERVKEDDLD VVLSPQRRSF GGGCHVTAAV SSRRSGSPLE KDSDGLRLLG
160 170 180 190 200
GRRIGSGRII SARAFEKDHR LSDKDLRDLR DRDRERDYKD KRFRREFGDS
210 220 230 240 250
KRVFGERRRN DSYTEEEPEW FSAGPTSQSE TIELTGFDDK ILEEDHKGRK
260 270 280 290 300
RTGRRTASVK EGIVECNGGV AEEDEVEVIL AQEPSADQEV PRDVILPEQS
310 320 330 340 350
PGEFDFNEFF NLDKVPCLAS MIEDVLGEGS VSASRFSRWF SNPSRSGSRS
360 370 380 390 400
SSLGSTPHEE LERLAGLEQA VLSPGQNSGN YFAPIPSEDH AENKVDILEM
410 420 430 440 450
LQKAKVDLKP LLSSLSANKE KLKESSHSGV VLSVEEVEAG LKGLKVDQQM
460 470 480 490 500
KNSTPFMAEH LEETLSAASS NRQLKKDGDM TAFNKLVNTM KASGTLPTQP
510 520 530 540 550
KVSELLGQPV QRPASSNLLS GLMGSLEATA SLLSQRAPSP PMSQVFRTQA
560 570 580 590 600
ASADYLHPRI PSPIGFPSGP QQLLGDPFQG MRKPMSPVSA QMSQLELQQA
610 620 630 640 650
ALEGLALPHD LAVQTAPFYQ PGFSKPQVDR TRDGLRNRQQ RMSKSPAPMH
660 670 680 690 700
GGNSSSPAPA ASITSMLSPS FTPTSVIRKM YESREKTKEE MAPGMVVPGD
710 720 730 740 750
DKEDTQKTSE ENLLSSNPIP NTDQDSFTTN PKLSTLQRSS CSTPLSQTSR
760 770 780 790 800
YTKEQDYRPK TAGRKTPTLA SPVPGTPFLR PTHQVPLVPH VPIVRPAHQL
810 820 830 840 850
HPGLVQRLIA QGVHPQHLPS LLQAGVLPPG IDMAPLQGLS GPLLGQPLYP
860 870 880 890 900
LVSAASHPLL NPRPGTPLHL AVMQQQLQRS VLHPPGSSSQ AAAISVQTPQ
910 920 930 940 950
NVPSRSGMPH MHSQLEHRTS QRSSSPVGLA KWFGSDVLQQ PLPSMPTKVI

SVDELEYRQ
Length:959
Mass (Da):105,412
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6CEBB3DEBEE9D3C6
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK041598 mRNA Translation: BAC30999.1

NCBI Reference Sequences

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RefSeqi
NP_001160020.1, NM_001166548.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
74203

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK041598 mRNA Translation: BAC30999.1
RefSeqiNP_001160020.1, NM_001166548.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ8BY82

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
74203

Genome annotation databases

GeneIDi74203

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56478
MGIiMGI:1921453, Eif4enif1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
74203, 10 hits in 62 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Eif4enif1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

GenevisibleiQ8BY82, MM

Family and domain databases

InterProiView protein in InterPro
IPR018862, eIF4E-T
PANTHERiPTHR12269, PTHR12269, 1 hit
PfamiView protein in Pfam
PF10477, EIF4E-T, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8BY82_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BY82
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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