UniProtKB - Q8BXS7 (GP152_MOUSE)
Protein
Probable G-protein coupled receptor 152
Gene
Gpr152
Organism
Mus musculus (Mouse)
Status
Functioni
Orphan receptor.
GO - Molecular functioni
- G protein-coupled receptor activity Source: GO_Central
- identical protein binding Source: MGI
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: GO_Central
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Names & Taxonomyi
Protein namesi | Recommended name: Probable G-protein coupled receptor 152 |
Gene namesi | Name:Gpr152 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2685519, Gpr152 |
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 33 | ExtracellularSequence analysisAdd BLAST | 33 | |
Transmembranei | 34 – 54 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 55 – 65 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 66 – 86 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 87 – 105 | ExtracellularSequence analysisAdd BLAST | 19 | |
Transmembranei | 106 – 126 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 127 – 148 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 149 – 169 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 170 – 194 | ExtracellularSequence analysisAdd BLAST | 25 | |
Transmembranei | 195 – 215 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 216 – 258 | CytoplasmicSequence analysisAdd BLAST | 43 | |
Transmembranei | 259 – 279 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 280 – 282 | ExtracellularSequence analysis | 3 | |
Transmembranei | 283 – 303 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 304 – 511 | CytoplasmicSequence analysisAdd BLAST | 208 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000069636 | 1 – 511 | Probable G-protein coupled receptor 152Add BLAST | 511 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 104 ↔ 182 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondProteomic databases
PaxDbi | Q8BXS7 |
PRIDEi | Q8BXS7 |
PTM databases
iPTMneti | Q8BXS7 |
PhosphoSitePlusi | Q8BXS7 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000044724, Expressed in retinal neural layer and 69 other tissues |
Genevisiblei | Q8BXS7, MM |
Interactioni
GO - Molecular functioni
- identical protein binding Source: MGI
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000094062 |
Miscellaneous databases
RNActi | Q8BXS7, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502SP7R, Eukaryota |
GeneTreei | ENSGT01010000222443 |
HOGENOMi | CLU_587370_0_0_1 |
InParanoidi | Q8BXS7 |
OMAi | YYFLWGV |
OrthoDBi | 1256901at2759 |
PhylomeDBi | Q8BXS7 |
TreeFami | TF338313 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027313, GPR152_orphan_prd IPR026234, MRGPCRFAMILY |
PANTHERi | PTHR11334, PTHR11334, 1 hit PTHR11334:SF1, PTHR11334:SF1, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8BXS7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDTAVEANLG AAGHGPRTEL SDEDYYPQGS WDTVFLVALL LLGLPANGLM
60 70 80 90 100
AWLAGSQARH GAGTRLALLL LSLALSDFLF LAAATFQILE IQHGGHWPLG
110 120 130 140 150
TAACRFYYFL WGVSYSSGLF LLTALSLDRC LLALCPRWYP GHRPARLPLW
160 170 180 190 200
VCAGVWVLAT LFSVPWLVFP EAAVWWYDLV ICLDFWDTEE LPLRMLEILG
210 220 230 240 250
GFLPFLLLLV CHVLTQATAC RTCCGHQPRR MACHGFARVA KTILSAYVVL
260 270 280 290 300
RLPYQLAQLL YLAFLWDVYP GYLLWEALVY SDYLILLNSC LSPFLCLAAS
310 320 330 340 350
ADLRALLRTV LSSFAAAVCE ERPGSFIPAE PQTLPGPTSE GQSRLDSVVQ
360 370 380 390 400
PQVNPSVQLQ SDSVVQPEVS PSAQPQSDSV AQPTVGSLIQ PPLDTVVQLE
410 420 430 440 450
VNPLTQPQLD PMAQPQVNPS AQPQSKSVVQ PQVDPLTQPQ LDPVAQPQSN
460 470 480 490 500
TETPIPAFGD ESASNPGEEN SSGPCPDPTP GTPENLDRPA VPQEKSPSNV
510
PPEEAPSAGP T
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK044366 mRNA Translation: BAC31886.1 BC099681 mRNA Translation: AAH99681.1 |
CCDSi | CCDS29417.1 |
RefSeqi | NP_996856.1, NM_206973.2 |
Genome annotation databases
Ensembli | ENSMUST00000096338; ENSMUSP00000094062; ENSMUSG00000044724 ENSMUST00000181548; ENSMUSP00000137706; ENSMUSG00000097905 |
GeneIDi | 269053 |
KEGGi | mmu:269053 |
UCSCi | uc008fyx.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK044366 mRNA Translation: BAC31886.1 BC099681 mRNA Translation: AAH99681.1 |
CCDSi | CCDS29417.1 |
RefSeqi | NP_996856.1, NM_206973.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000094062 |
Protein family/group databases
GPCRDBi | Search... |
PTM databases
iPTMneti | Q8BXS7 |
PhosphoSitePlusi | Q8BXS7 |
Proteomic databases
PaxDbi | Q8BXS7 |
PRIDEi | Q8BXS7 |
Protocols and materials databases
Antibodypediai | 16520, 157 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000096338; ENSMUSP00000094062; ENSMUSG00000044724 ENSMUST00000181548; ENSMUSP00000137706; ENSMUSG00000097905 |
GeneIDi | 269053 |
KEGGi | mmu:269053 |
UCSCi | uc008fyx.1, mouse |
Organism-specific databases
CTDi | 390212 |
MGIi | MGI:2685519, Gpr152 |
Phylogenomic databases
eggNOGi | ENOG502SP7R, Eukaryota |
GeneTreei | ENSGT01010000222443 |
HOGENOMi | CLU_587370_0_0_1 |
InParanoidi | Q8BXS7 |
OMAi | YYFLWGV |
OrthoDBi | 1256901at2759 |
PhylomeDBi | Q8BXS7 |
TreeFami | TF338313 |
Miscellaneous databases
BioGRID-ORCSi | 269053, 0 hits in 17 CRISPR screens |
ChiTaRSi | Gpr152, mouse |
PROi | PR:Q8BXS7 |
RNActi | Q8BXS7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000044724, Expressed in retinal neural layer and 69 other tissues |
Genevisiblei | Q8BXS7, MM |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR027313, GPR152_orphan_prd IPR026234, MRGPCRFAMILY |
PANTHERi | PTHR11334, PTHR11334, 1 hit PTHR11334:SF1, PTHR11334:SF1, 1 hit |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GP152_MOUSE | |
Accessioni | Q8BXS7Primary (citable) accession number: Q8BXS7 Secondary accession number(s): Q499X3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2004 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families - 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries