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UniProtKB - Q8BWW4 (LARP4_MOUSE)

Entry version 130 (02 Jun 2021)
Sequence version 2 (16 May 2006)
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Protein

La-related protein 4

Gene

Larp4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA binding protein that binds to the poly-A tract of mRNA molecules. Associates with the 40S ribosomal subunit and with polysomes. Plays a role in the regulation of mRNA translation. Plays a role in the regulation of cell morphology and cytoskeletal organization.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processProtein biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
La-related protein 4
Alternative name(s):
La ribonucleoprotein domain family member 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Larp4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2443114, Larp4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002076121 – 719La-related protein 4Add BLAST719

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei363Omega-N-methylarginineBy similarity1
Modified residuei387PhosphoserineBy similarity1
Modified residuei396PhosphoserineCombined sources1
Modified residuei500PhosphoserineBy similarity1
Modified residuei578PhosphoserineBy similarity1
Modified residuei592PhosphoserineBy similarity1
Modified residuei642PhosphoserineBy similarity1
Modified residuei644PhosphothreonineBy similarity1
Modified residuei681Omega-N-methylarginineBy similarity1
Modified residuei717PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8BWW4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8BWW4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8BWW4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8BWW4

PRoteomics IDEntifications database

More...PRIDEi		Q8BWW4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		265042

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8BWW4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8BWW4

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q8BWW4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminal region) with PABPC1.

Interacts with RACK1.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		228885, 4 interactors

Protein interaction database and analysis system

More...IntActi		Q8BWW4, 2 interactors

Molecular INTeraction database

More...MINTi		Q8BWW4

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000097780

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8BWW4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8BWW4

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini109 – 198HTH La-type RNA-bindingPROSITE-ProRule annotationAdd BLAST90
Domaini199 – 277RRMAdd BLAST79

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni12 – 21Interaction with PABPC1By similarity10
Regioni21 – 55DisorderedSequence analysisAdd BLAST35
Regioni107 – 299Interaction with the poly-A tract of mRNABy similarityAdd BLAST193
Regioni363 – 398DisorderedSequence analysisAdd BLAST36
Regioni437 – 470DisorderedSequence analysisAdd BLAST34
Regioni529 – 562DisorderedSequence analysisAdd BLAST34
Regioni576 – 601DisorderedSequence analysisAdd BLAST26
Regioni615 – 719DisorderedSequence analysisAdd BLAST105

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi21 – 51Polar residuesSequence analysisAdd BLAST31
Compositional biasi377 – 398Polar residuesSequence analysisAdd BLAST22
Compositional biasi438 – 459Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi650 – 671Basic and acidic residuesSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2590, Eukaryota
KOG2591, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8BWW4

Database of Orthologous Groups

More...OrthoDBi		263288at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8BWW4

Family and domain databases

Conserved Domains Database

More...CDDi		cd12707, RRM_LARP4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006630, La_HTH
IPR034903, LARP4_RRM
IPR035979, RBD_domain_sf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05383, La, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00715, LA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46785, SSF46785, 1 hit
SSF54928, SSF54928, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50961, HTH_LA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q8BWW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLFVEVTSK GTGLNPNAKV WQEIPSGNPD GTPVTEPSWH ETAATSGSHP 
        60         70         80         90        100
EGHTELSEDM CKEYEVMYSP SCETTRNTAD VEESADGMIL GPEDLSYQLY 
       110        120        130        140        150
DVSGESSSAI STEDLKECLK KQLEFCFSRE NLSKDLYLIS QMDSDQFVPI 
       160        170        180        190        200
WTVANMEEIK KLTTNTDLIL EVLRSSPMVQ VDEKGEKVRP SHKRCIVILR 
       210        220        230        240        250
EIPETTPVEE VKALFKNENC PKVISCEFAH NSNWYITFQS DTDAQQAFKY 
       260        270        280        290        300
LREEVKTFQG KPIMARIKAI NTFFAKNGYR LMDSSMYTQP IQTPTQYPSP 
       310        320        330        340        350
VFMQPVYNPQ QYSVYSLVPQ SWSPSPAPYF ETPLAPFPNG SFVDGFSSPG 
       360        370        380        390        400
SYKTNAAAMN MGRPFPKNRV KPHFRSSSGS EHSTEGSVSL GDGPLSRSSS 
       410        420        430        440        450
RIFLSERHNP TVTGQQEQTY LPKEAPILQM EQNGDFGRGR RTLFRGRRRR 
       460        470        480        490        500
DDDRIPRPQP AATEAKAPTP KFDLLATNFP PLPGSSSRVP DELGLENRMS 
       510        520        530        540        550
DVVKGVCREK DSEDVRVSCP VPAEDGQTDC TSAPLSISPS PPCTAEPPVL 
       560        570        580        590        600
STTQQEQDQM EDSAVPKDTL NPVAVPVSSP TATKPSPANT ASPCTSNINP 
       610        620        630        640        650
PRAVALQEPR KLSYAEVCQK PPKEPSPVLV QPLRELRSNA VSPTRNEENG 
       660        670        680        690        700
APEKPVEKPH EKPETRASKD HSGFRGNTIP RGAAGKIREQ RRQFSHRATP 
       710 
QGVTRRNGKE QYVPPRSPK
Length:719
Mass (Da):79,763
Last modified:May 16, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB699A5FC5642023B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3X9Q6G3X9Q6_MOUSE
La-related protein 4
Larp4
719Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q066E9Q066_MOUSE
La-related protein 4
Larp4
718Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8VKL5A0A2R8VKL5_MOUSE
La-related protein 4
Larp4
660Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8W6Y5A0A2R8W6Y5_MOUSE
La-related protein 4
Larp4
610Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8VHW8A0A2R8VHW8_MOUSE
La-related protein 4
Larp4
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK049756 mRNA Translation: BAC33905.2
AK141743 mRNA Translation: BAE24819.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS37208.1

NCBI Reference Sequences

More...RefSeqi		NP_001019697.2, NM_001024526.2
NP_001074417.1, NM_001080948.2
NP_001271450.1, NM_001284521.1
NP_001271451.1, NM_001284522.1
NP_001271452.1, NM_001284523.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		207214

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:207214

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK049756 mRNA Translation: BAC33905.2
AK141743 mRNA Translation: BAE24819.1
CCDSiCCDS37208.1
RefSeqiNP_001019697.2, NM_001024526.2
NP_001074417.1, NM_001080948.2
NP_001271450.1, NM_001284521.1
NP_001271451.1, NM_001284522.1
NP_001271452.1, NM_001284523.1

3D structure databases

SMRiQ8BWW4
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi228885, 4 interactors
IntActiQ8BWW4, 2 interactors
MINTiQ8BWW4
STRINGi10090.ENSMUSP00000097780

PTM databases

iPTMnetiQ8BWW4
PhosphoSitePlusiQ8BWW4
SwissPalmiQ8BWW4

Proteomic databases

EPDiQ8BWW4
jPOSTiQ8BWW4
MaxQBiQ8BWW4
PaxDbiQ8BWW4
PRIDEiQ8BWW4
ProteomicsDBi265042

Genome annotation databases

GeneIDi207214
KEGGimmu:207214

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		113251
MGIiMGI:2443114, Larp4

Phylogenomic databases

eggNOGiKOG2590, Eukaryota
KOG2591, Eukaryota
InParanoidiQ8BWW4
OrthoDBi263288at2759
PhylomeDBiQ8BWW4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		207214, 14 hits in 54 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Larp4, mouse

Protein Ontology

More...PROi		PR:Q8BWW4
RNActiQ8BWW4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Family and domain databases

CDDicd12707, RRM_LARP4, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR006630, La_HTH
IPR034903, LARP4_RRM
IPR035979, RBD_domain_sf
IPR036388, WH-like_DNA-bd_sf
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF05383, La, 1 hit
SMARTiView protein in SMART
SM00715, LA, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
SSF54928, SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50961, HTH_LA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLARP4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BWW4
Secondary accession number(s): Q3UR69
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: May 16, 2006
Last modified: June 2, 2021
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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