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Entry version 106 (03 Jul 2019)
Sequence version 2 (13 Nov 2007)
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Protein

VPS35 endosomal protein sorting factor-like

Gene

Vps35l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
VPS35 endosomal protein sorting factor-likeCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Vps35lImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1918767 Vps35l

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei699 – 719HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endosome, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003113531 – 963VPS35 endosomal protein sorting factor-likeAdd BLAST963

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei265PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BWQ6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BWQ6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BWQ6

PeptideAtlas

More...
PeptideAtlasi
Q8BWQ6

PRoteomics IDEntifications database

More...
PRIDEi
Q8BWQ6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BWQ6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BWQ6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8BWQ6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030982 Expressed in 269 organ(s), highest expression level in fibroblast

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BWQ6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BWQ6 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the heterotrimeric retriever complex formed by VPS26C, VPS29 and VPS35L.

Interacts with COMMD1, CCDC93 and CCDC22; associates with the CCC (COMMD/CCDC22/CCDC93) complex which contains at least COMMD1 (and possibly other COMM domain-containing proteins), CCDC22 and CCDC93.

Interacts with WASHC1, WASHC2A and WASHC2C.

Interacts with SNX17 and SNX31.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
214753, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000051263

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi49 – 71Ser-richAdd BLAST23

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VPS35L family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3682 Eukaryota
ENOG410XQR5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011343

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BWQ6

Database of Orthologous Groups

More...
OrthoDBi
247677at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BWQ6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029705 VPS35L

The PANTHER Classification System

More...
PANTHERi
PTHR13673 PTHR13673, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BWQ6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAVFPWHSRN RNYKAELASC RLETVPLECG DYHPLKPITV TESKTKKVSR
60 70 80 90 100
KGSTSSTSSS SSSSVIDPLS SVLDGTDPLS MFAATSDPAA TGTVTDSSRK
110 120 130 140 150
KRDKDENSFV GPDFEPWANK RVEILARYTT TEKLSINLFM GSEKGRGGAA
160 170 180 190 200
ASAMSEKVRT RLEELDDFEE GSQKELLNLT QQDYVNRIEE LNQSLKDAWA
210 220 230 240 250
SDQKVKALKI VIQCSKLLSD TSVIQFYPSK FVLITDILDT FGKLVYERIS
260 270 280 290 300
SMCVDSRSAL PDHFSPENVN DTAKETCLNW FFKIASIREL IPRFYVEASI
310 320 330 340 350
LKCNKFLSKT GISECLPRLT CMIRGIGDPL VSVYARAYLC RVGIEVAPHL
360 370 380 390 400
KESLNKNFFD FLLTFKQIHG DTVQNQLVAQ GVELLSYLPL YSPAMGWIFQ
410 420 430 440 450
CVSYHAPEAL LTEMMERCKK LGNNALLLNS VMSAFRAEFV ATRSMDFIGM
460 470 480 490 500
IKECDESGFP KHLLFRSLGL NLALADPPEN DRLQILNEAW KVITKLKSPQ
510 520 530 540 550
DYINCAEVWV EYTCRHFTKR EVNTVLADVI KHMTPDRAFE DSYPQLQSII
560 570 580 590 600
QKVIAHFHDF SVLFSVEKFL PFLDMFQKES VRVEVCKCIM EAFIKHQQEP
610 620 630 640 650
TKDPVILNAL LHICKTMHDS VNALTLEDEK RTLAHLINGF IKMVSFGRDF
660 670 680 690 700
EQQLSFYVES RSMFCNLEPV LVQLIHSVNR LAMETRKVMK GNHSRKTAAF
710 720 730 740 750
VRACVAYCFI TIPSLVGIFT RLNLYLHSGQ VALANQCLSQ ADAFFKAAIG
760 770 780 790 800
LVPEVPKTIS IDGKLRPSEP FLLEFLCNFF STLLIVPDHP EHGVLFLVRE
810 820 830 840 850
LLNVIQDYTW EDSSDDKIRI YTSVLHLLSA MSQDTYLYHI DKVDSNDSLY
860 870 880 890 900
GGDSKFLAEN SKLCEAVMAQ ILEHLKTLAK DEALKRQSLL GLSFFNSILA
910 920 930 940 950
HGDLRNNKLN QLSVNLWHLA QRHGCADTRT MVKTLDYIKK RSKQPDMNHL
960
SELALRLPLQ TRT
Length:963
Mass (Da):109,077
Last modified:November 13, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A7A7A73FDBDF740
GO
Isoform 2 (identifier: Q8BWQ6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     409-434: ALLTEMMERCKKLGNNALLLNSVMSA → CALSSLPSLLSELRGLSHLWRCAEAV
     435-963: Missing.

Note: No experimental confirmation available.
Show »
Length:434
Mass (Da):48,439
Checksum:iEB7571165ECAB71F
GO
Isoform 3 (identifier: Q8BWQ6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-235: Missing.
     236-241: DILDTF → MLLAGH

Note: No experimental confirmation available.
Show »
Length:728
Mass (Da):82,999
Checksum:i8ECCC39C174A83AD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6RR19F6RR19_MOUSE
VPS35 endosomal protein sorting fac...
Vps35l 9030624J02Rik, Vsp35l
203Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I1E4X5I1E4X5_MOUSE
VPS35 endosomal protein sorting fac...
Vps35l 9030624J02Rik, Vsp35l
991Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YW19D3YW19_MOUSE
VPS35 endosomal protein sorting fac...
Vps35l 9030624J02Rik, Vsp35l
940Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YW20D3YW20_MOUSE
VPS35 endosomal protein sorting fac...
Vps35l 9030624J02Rik, Vsp35l
874Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BJE8H3BJE8_MOUSE
VPS35 endosomal protein sorting fac...
Vps35l 9030624J02Rik, Vsp35l
245Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti208L → V in BAE22841 (PubMed:16141072).Curated1
Sequence conflicti632T → M in AAH07154 (PubMed:15489334).Curated1
Sequence conflicti632T → M in AAH25808 (PubMed:15489334).Curated1
Sequence conflicti759I → M in BAE22543 (PubMed:16141072).Curated1
Sequence conflicti781S → C in BAC34176 (PubMed:16141072).Curated1
Sequence conflicti785I → M in AAH25808 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0295391 – 235Missing in isoform 3. 1 PublicationAdd BLAST235
Alternative sequenceiVSP_029540236 – 241DILDTF → MLLAGH in isoform 3. 1 Publication6
Alternative sequenceiVSP_029541409 – 434ALLTE…SVMSA → CALSSLPSLLSELRGLSHLW RCAEAV in isoform 2. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_029542435 – 963Missing in isoform 2. 1 PublicationAdd BLAST529

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK018573 mRNA Translation: BAB31285.1
AK050302 mRNA Translation: BAC34176.1
AK135468 mRNA Translation: BAE22543.1
AK136140 mRNA Translation: BAE22841.1
BC007154 mRNA Translation: AAH07154.1
BC025808 mRNA Translation: AAH25808.1
BC043674 mRNA Translation: AAH43674.1
BC054720 mRNA Translation: AAH54720.1

NCBI Reference Sequences

More...
RefSeqi
NP_082091.3, NM_027815.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000033280; ENSMUSP00000033280; ENSMUSG00000030982 [Q8BWQ6-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
71517

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:71517

UCSC genome browser

More...
UCSCi
uc009jkp.2 mouse [Q8BWQ6-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018573 mRNA Translation: BAB31285.1
AK050302 mRNA Translation: BAC34176.1
AK135468 mRNA Translation: BAE22543.1
AK136140 mRNA Translation: BAE22841.1
BC007154 mRNA Translation: AAH07154.1
BC025808 mRNA Translation: AAH25808.1
BC043674 mRNA Translation: AAH43674.1
BC054720 mRNA Translation: AAH54720.1
RefSeqiNP_082091.3, NM_027815.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi214753, 1 interactor
STRINGi10090.ENSMUSP00000051263

PTM databases

iPTMnetiQ8BWQ6
PhosphoSitePlusiQ8BWQ6
SwissPalmiQ8BWQ6

Proteomic databases

EPDiQ8BWQ6
jPOSTiQ8BWQ6
PaxDbiQ8BWQ6
PeptideAtlasiQ8BWQ6
PRIDEiQ8BWQ6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000033280; ENSMUSP00000033280; ENSMUSG00000030982 [Q8BWQ6-3]
GeneIDi71517
KEGGimmu:71517
UCSCiuc009jkp.2 mouse [Q8BWQ6-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57020
MGIiMGI:1918767 Vps35l

Phylogenomic databases

eggNOGiKOG3682 Eukaryota
ENOG410XQR5 LUCA
GeneTreeiENSGT00390000011343
InParanoidiQ8BWQ6
OrthoDBi247677at2759
PhylomeDBiQ8BWQ6

Enzyme and pathway databases

ReactomeiR-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8BWQ6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030982 Expressed in 269 organ(s), highest expression level in fibroblast
ExpressionAtlasiQ8BWQ6 baseline and differential
GenevisibleiQ8BWQ6 MM

Family and domain databases

InterProiView protein in InterPro
IPR029705 VPS35L
PANTHERiPTHR13673 PTHR13673, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVP35L_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BWQ6
Secondary accession number(s): Q3UWS3
, Q3UXM0, Q7TQF5, Q80XN3, Q8R3A8, Q91VY3, Q9D307
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 13, 2007
Last modified: July 3, 2019
This is version 106 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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