Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 17 of 17  Show
  1. 1
    "IAN family critically regulates survival and development of T lymphocytes."
    Nitta T., Nasreen M., Seike T., Goji A., Ohigashi I., Miyazaki T., Ohta T., Kanno M., Takahama Y.
    PLoS Biol. 4:593-605(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH BAD; BAK1; BAX; BCL2; BCL2L1 AND BCL2L11, DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.
    Category: Function, Expression, Interaction, Sequences.
    Tissue: Thymocyte.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 19 and mapped to 6 other entries.

  2. 2
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Kidney.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10626 and mapped to 43943 other entries.

  3. 3
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Strain: C57BL/6J.
    Tissue: Kidney.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50446 other entries.

  4. 4
    "Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5."
    Schulteis R.D., Chu H., Dai X., Chen Y., Edwards B., Haribhai D., Williams C.B., Malarkannan S., Hessner M.J., Glisic-Milosavljevic S., Jana S., Kerschen E.J., Ghosh S., Wang D., Kwitek A.E., Lernmark A., Gorski J., Weiler H.
    Blood 112:4905-4914(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    Category: Function, Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  5. 5
    Cited for: SUBCELLULAR LOCATION.
    Category: Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 other entries.

  6. 6
    "Critical role for Gimap5 in the survival of mouse hematopoietic stem and progenitor cells."
    Chen Y., Yu M., Dai X., Zogg M., Wen R., Weiler H., Wang D.
    J. Exp. Med. 208:923-935(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH BCL2; BCL2L1; HSPA8 AND MCL1, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.
    Category: Function, Pathology & Biotech, Expression, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  7. 7
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  8. 8
    "Gimap5-dependent inactivation of GSK3beta is required for CD4+ T cell homeostasis and prevention of immune pathology."
    Patterson A.R., Endale M., Lampe K., Aksoylar H.I., Flagg A., Woodgett J.R., Hildeman D., Jordan M.B., Singh H., Kucuk Z., Bleesing J., Hoebe K.
    Nat. Commun. 9:430-430(2018) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
    Category: Function, Subcellular Location.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 8 other entries.

  9. 9
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:2442232.

    This publication is cited by 16983 and mapped to 41374 other entries.

  10. 10
    "Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery."
    Barnes M.J., Krebs P., Harris N., Eidenschenk C., Gonzalez-Quintial R., Arnold C.N., Crozat K., Sovath S., Moresco E.M., Theofilopoulos A.N., Beutler B., Hoebe K.
    PLoS Biol. 7:e51-e51(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: MGI:2442232.

    This publication is mapped to 2 other entries.

  11. 11
    "Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice."
    Barnes M.J., Aksoylar H., Krebs P., Bourdeau T., Arnold C.N., Xia Y., Khovananth K., Engel I., Sovath S., Lampe K., Laws E., Saunders A., Butcher G.W., Kronenberg M., Steinbrecher K., Hildeman D., Grimes H.L., Beutler B., Hoebe K.
    J. Immunol. 184:3743-3754(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:2442232.

    This publication is mapped to 27 other entries.

  12. 12
    Category: Function, Pathology & Biotech.
    Source: MGI:2442232.

    This publication is mapped to 34959 other entries.

  13. 13
    "Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells."
    Aksoylar H.I., Lampe K., Barnes M.J., Plas D.R., Hoebe K.
    J. Immunol. 188:146-154(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: a novel link between Gimap5 and Foxo expression and provide evidence for a regulatory mechanism that controls Foxo protein expression and may help to maintain immunological tolerance. [GeneRIF:317757].
    Source: GeneRIF:317757, MGI:2442232.
  14. 14
    Category: Function, Pathology & Biotech.
    Annotation: The defects in T-cell cellularity were more severe in mice lacking both Gimap3 and Gimap5. [GeneRIF:317757].
    Source: GeneRIF:317757, MGI:2442232.

    This publication is mapped to 1 other entry.

  15. 15
    "Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut."
    Endale M., Aksoylar H.I., Hoebe K.
    Mediators Inflamm. 2015:436017-436017(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: gimap5 has a role in maintaining peripheral tolerance and T cell homeostasis in the gut (review).
    Source: GeneRIF:317757.

    This publication is mapped to 3 other entries.

  16. 16
    "TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)."
    Chen X.L., Serrano D., Ghobadi F., Mayhue M., Hoebe K., Ilangumaran S., Ramanathan S.
    PLoS ONE 11:e0151837-e0151837(2016) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells. [GeneRIF:317757].
    Source: GeneRIF:317757, MGI:2442232.

    This publication is mapped to 7 other entries.

  17. 17
    "Loss of GTPase of immunity-associated protein 5 (Gimap5) promotes pathogenic CD4+ T-cell development and allergic airway disease."
    Patterson A.R., Bolcas P., Lampe K., Cantrell R., Ruff B., Lewkowich I., Hogan S.P., Janssen E.M., Bleesing J., Khurana Hershey G.K., Hoebe K.
    J. Allergy Clin. Immunol. 143:245-257.e6(2019) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Activation of Gimap5-deficient CD4(+) T cells is associated with increased DNA damage and reduced survival that can be overcome by TGF-beta. This leads to selective survival of pathogenic TH17 cells but also TH2 cells in human subjects and mice ultimately promoting allergic airway disease. [GeneRIF:317757].
    Source: GeneRIF:317757, MGI:2442232.
1 to 17 of 17  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again