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UniProtKB - Q8BTY8 (SCFD2_MOUSE)

Entry version 116 (02 Dec 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Sec1 family domain-containing protein 2

Gene

Scfd2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in protein transport.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • syntaxin binding Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sec1 family domain-containing protein 2
Alternative name(s):
Neuronal Sec1
Syntaxin-binding protein 1-like 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Scfd2
Synonyms:Stxbp1l1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2443446, Scfd2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002062911 – 684Sec1 family domain-containing protein 2Add BLAST684

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8BTY8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8BTY8

PeptideAtlas

More...PeptideAtlasi		Q8BTY8

PRoteomics IDEntifications database

More...PRIDEi		Q8BTY8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8BTY8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8BTY8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000062110, Expressed in pancreas and 199 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8BTY8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000072636

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8BTY8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi120 – 124Poly-Ala5

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the STXBP/unc-18/SEC1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QQIB, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011192

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_027230_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8BTY8

Identification of Orthologs from Complete Genome Data

More...OMAi		MIKPSNQ

Database of Orthologous Groups

More...OrthoDBi		277043at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8BTY8

TreeFam database of animal gene trees

More...TreeFami		TF329842

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.1910, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027482, Sec-1-like_dom2
IPR001619, Sec1-like
IPR036045, Sec1-like_sf

The PANTHER Classification System

More...PANTHERi		PTHR11679, PTHR11679, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00995, Sec1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56815, SSF56815, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BTY8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSAAGILAFA QQGWEQVLAK VKWSVVYLDA ACAESLHWSC GSSRLLEAVK 
        60         70         80         90        100
GPACHLREFE PQAIGGGAKQ PRAVFVLSSP LKGRIVDTLQ SIICRSHFQH 
       110        120        130        140        150
CVVVTAVSHA VHLTANHVPA AAAAELEGQQ PVFEQLEEKL CEWMGNENYT 
       160        170        180        190        200
AEVLHVPLFL APVASHLAFT PAFATLFPLL PQDVHALNSA RPDKRRLSSL 
       210        220        230        240        250
GEVDATALTP ELLLYIRCLV SGLSSLCEHL GVREECFAVG PLSRVIATDL 
       260        270        280        290        300
ANYAPAKNRK KTATGRASVV FVDRTLDLTG AVGHHGDNLV EKIMSVLPQL 
       310        320        330        340        350
PGHTHDVMVN MAELTAVQAV EENQNVIAPG CLAPSNEASA KALWEALLNS 
       360        370        380        390        400
KHKEAVMEVR RHLVEAASRE NLPIKMSMGR VTPGQLMSYI QLFKNNLRAL 
       410        420        430        440        450
RNHCGLLQLG MATVQTLKHP QTAKWDNFLA FERLLLQSLG DSTMAGVLNQ 
       460        470        480        490        500
LLPMIKSSSQ RTSDDLNPEE LLILLIYIYS VPGDVTLDRD LGDVEEKVKK 
       510        520        530        540        550
ALAHVLSEES ELSPLLQKIT GCDSAVDLTL PKSQIAVNDV FMALREIAGA 
       560        570        580        590        600
RNLMRQFKSV YVPGNNTHQA SYKPLLKQVV EEIFNPEKSD PIDIEHMSSG 
       610        620        630        640        650
LTDLLKTGFS MFMKVSRPHP SDHPLLILFV VGGVTVAEAK MVKDLVASLK 
       660        670        680 
PGTQVMVLST RLLKPLNIPE LLFATDRLHP DLGF
Length:684
Mass (Da):74,751
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i96F00899480022D5
GO
Isoform 2 (identifier: Q8BTY8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     615-654: Missing.

Show »
Length:644
Mass (Da):70,561
Checksum:i987736CB4E62161B
GO
Isoform 3 (identifier: Q8BTY8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     438-477: SLGDSTMAGV...PEELLILLIY → CSFVLRACGH...HPPHGCPFIP
     478-684: Missing.

Show »
Length:477
Mass (Da):52,029
Checksum:iE675A3D924CD6C96
GO
Isoform 4 (identifier: Q8BTY8-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-143: Missing.
     438-477: SLGDSTMAGV...PEELLILLIY → CSFVLRACGH...HPPHGCPFIP
     478-684: Missing.

Show »
Length:334
Mass (Da):36,593
Checksum:iD1EB81E94A32A9B4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0J9YVF7A0A0J9YVF7_MOUSE
Sec1 family domain-containing prote...
Scfd2
51Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC32943 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC34373 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti89L → V in BAC29514 (PubMed:16141072).Curated1
Sequence conflicti234E → G in BAC31906 (PubMed:16141072).Curated1
Sequence conflicti234E → G in BAC34373 (PubMed:16141072).Curated1
Sequence conflicti368S → R in BAC29514 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0107111 – 143Missing in isoform 4. 1 PublicationAdd BLAST143
Alternative sequenceiVSP_010712438 – 477SLGDS…ILLIY → CSFVLRACGHLLHSCHGTML PPVPRQPPWVHPPHGCPFIP in isoform 3 and isoform 4. 2 PublicationsAdd BLAST40
Alternative sequenceiVSP_010713478 – 684Missing in isoform 3 and isoform 4. 2 PublicationsAdd BLAST207
Alternative sequenceiVSP_010714615 – 654Missing in isoform 2. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK036637 mRNA Translation: BAC29514.1
AK044408 mRNA Translation: BAC31906.1
AK047026 mRNA Translation: BAC32943.1 Different initiation.
AK047738 mRNA Translation: BAC33143.1
AK050673 mRNA Translation: BAC34373.1 Different initiation.
AK054548 mRNA Translation: BAC35820.1
AK088353 mRNA Translation: BAC40298.1
AK089011 mRNA Translation: BAC40699.1
AK140246 mRNA Translation: BAE24296.1
BC042528 mRNA Translation: AAH42528.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS19345.1 [Q8BTY8-3]
CCDS51519.1 [Q8BTY8-1]
CCDS71603.1 [Q8BTY8-2]

NCBI Reference Sequences

More...RefSeqi		NP_001108132.1, NM_001114660.2 [Q8BTY8-1]
NP_001273366.1, NM_001286437.1 [Q8BTY8-2]
NP_848787.2, NM_178672.7 [Q8BTY8-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000072857; ENSMUSP00000072636; ENSMUSG00000062110 [Q8BTY8-1]
ENSMUST00000075848; ENSMUSP00000075245; ENSMUSG00000062110 [Q8BTY8-3]
ENSMUST00000113542; ENSMUSP00000109170; ENSMUSG00000062110 [Q8BTY8-2]
ENSMUST00000151474; ENSMUSP00000121098; ENSMUSG00000062110 [Q8BTY8-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		212986

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:212986

UCSC genome browser

More...UCSCi		uc008xtk.3, mouse [Q8BTY8-1]
uc012dxh.2, mouse [Q8BTY8-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK036637 mRNA Translation: BAC29514.1
AK044408 mRNA Translation: BAC31906.1
AK047026 mRNA Translation: BAC32943.1 Different initiation.
AK047738 mRNA Translation: BAC33143.1
AK050673 mRNA Translation: BAC34373.1 Different initiation.
AK054548 mRNA Translation: BAC35820.1
AK088353 mRNA Translation: BAC40298.1
AK089011 mRNA Translation: BAC40699.1
AK140246 mRNA Translation: BAE24296.1
BC042528 mRNA Translation: AAH42528.1
CCDSiCCDS19345.1 [Q8BTY8-3]
CCDS51519.1 [Q8BTY8-1]
CCDS71603.1 [Q8BTY8-2]
RefSeqiNP_001108132.1, NM_001114660.2 [Q8BTY8-1]
NP_001273366.1, NM_001286437.1 [Q8BTY8-2]
NP_848787.2, NM_178672.7 [Q8BTY8-3]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000072636

PTM databases

iPTMnetiQ8BTY8
PhosphoSitePlusiQ8BTY8

Proteomic databases

EPDiQ8BTY8
PaxDbiQ8BTY8
PeptideAtlasiQ8BTY8
PRIDEiQ8BTY8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		23902, 70 antibodies

Genome annotation databases

EnsembliENSMUST00000072857; ENSMUSP00000072636; ENSMUSG00000062110 [Q8BTY8-1]
ENSMUST00000075848; ENSMUSP00000075245; ENSMUSG00000062110 [Q8BTY8-3]
ENSMUST00000113542; ENSMUSP00000109170; ENSMUSG00000062110 [Q8BTY8-2]
ENSMUST00000151474; ENSMUSP00000121098; ENSMUSG00000062110 [Q8BTY8-3]
GeneIDi212986
KEGGimmu:212986
UCSCiuc008xtk.3, mouse [Q8BTY8-1]
uc012dxh.2, mouse [Q8BTY8-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		152579
MGIiMGI:2443446, Scfd2

Phylogenomic databases

eggNOGiENOG502QQIB, Eukaryota
GeneTreeiENSGT00390000011192
HOGENOMiCLU_027230_1_0_1
InParanoidiQ8BTY8
OMAiMIKPSNQ
OrthoDBi277043at2759
PhylomeDBiQ8BTY8
TreeFamiTF329842

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		212986, 0 hits in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Scfd2, mouse

Protein Ontology

More...PROi		PR:Q8BTY8
RNActiQ8BTY8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000062110, Expressed in pancreas and 199 other tissues
GenevisibleiQ8BTY8, MM

Family and domain databases

Gene3Di3.40.50.1910, 1 hit
InterProiView protein in InterPro
IPR027482, Sec-1-like_dom2
IPR001619, Sec1-like
IPR036045, Sec1-like_sf
PANTHERiPTHR11679, PTHR11679, 1 hit
PfamiView protein in Pfam
PF00995, Sec1, 1 hit
SUPFAMiSSF56815, SSF56815, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCFD2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BTY8
Secondary accession number(s): Q3USN5
, Q8BFV9, Q8BKU5, Q8BKZ0, Q8BTP6, Q8BTQ9, Q8BXI1, Q8BXS0, Q8BZ58
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2004
Last sequence update: March 1, 2003
Last modified: December 2, 2020
This is version 116 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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