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Entry version 119 (17 Jun 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Leukocyte receptor cluster member 9

Gene

Leng9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri8 – 35C3H1-typePROSITE-ProRule annotationAdd BLAST28

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leukocyte receptor cluster member 9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Leng9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444509 Leng9

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004158261 – 485Leukocyte receptor cluster member 9Add BLAST485

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8BTN6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BTN6

PeptideAtlas

More...
PeptideAtlasi
Q8BTN6

PRoteomics IDEntifications database

More...
PRIDEi
Q8BTN6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BTN6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BTN6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000043432 Expressed in intestine and 132 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BTN6 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000061079

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BTN6 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q8BTN6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri8 – 35C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IWVT Eukaryota
ENOG4111GEQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010577

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_044135_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BTN6

Identification of Orthologs from Complete Genome Data

More...
OMAi
PTHFICF

Database of Orthologous Groups

More...
OrthoDBi
1210602at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BTN6

TreeFam database of animal gene trees

More...
TreeFami
TF329287

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009097 Cyclic_Pdiesterase
IPR019510 Kinase-A_anchor_nucl_local_sig
IPR042653 Leng9
IPR040459 MJ1316
IPR041367 Znf-CCCH_4
IPR000571 Znf_CCCH

The PANTHER Classification System

More...
PANTHERi
PTHR46729 PTHR46729, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10469 AKAP7_NLS, 1 hit
PF04457 MJ1316, 1 hit
PF18044 zf-CCCH_4, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00356 ZnF_C3H1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55144 SSF55144, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50103 ZF_C3H1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8BTN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEASADSSEA PAVCRFFLEG RCRFGARCRQ PHPGAPAPSP VVTQPEAGSK
60 70 80 90 100
KPALRTAADV IRRIRWDPRL DPADFSVGYT DRFLGVQEEP FCAFCWDEPL
110 120 130 140 150
AALGPGVLAV PQHRIRYFRF RGRLVWDRAS RTDLIFGSGS VAGRGPTILD
160 170 180 190 200
ALDGGDEHWT EVTAEIPDTE KTGVGLEGLD TQDALAEAGG NPTGTGLDSG
210 220 230 240 250
LETHEEGGAI KETRTGLDSS LETPEVDGPT KETGLNGTTE LEMPDPSMNF
260 270 280 290 300
SGVKISSVEE PRATLLPQWQ AQGMETKGLS AEEMGNVWDP GVWPDDRRAP
310 320 330 340 350
RQPRPTHFVA LMVTESGLRA EVVKAQEHLV RIAPSCAEFL VPAQALHLTV
360 370 380 390 400
VLLRLTGPGE EAAAARALRR AILKPGLQAP SQLQFRDLVL LGHHVLCATP
410 420 430 440 450
SPTLTGMAQT LNQRLEAEGL RVVLLPELQP HLTLAKVPHG TQVCLPKPEY
460 470 480
TLNQELGRQP LSKLWLCRMG RAGHSYLPLV EISLK
Length:485
Mass (Da):52,613
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i98B03A4379141E21
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti62R → G in BAE22187 (PubMed:16141072).Curated1
Sequence conflicti63R → G in BAC41185 (PubMed:16141072).Curated1
Sequence conflicti398A → V in BAC41185 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK089196 mRNA Translation: BAC40788.1
AK090365 mRNA Translation: BAC41185.1
AK134559 mRNA Translation: BAE22187.1
AK147019 mRNA Translation: BAE27612.1
AC101941 Genomic DNA No translation available.
BC116676 mRNA Translation: AAI16677.1
CH466627 Genomic DNA Translation: EDL31225.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20732.1

NCBI Reference Sequences

More...
RefSeqi
NP_780738.1, NM_175529.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000058358; ENSMUSP00000061079; ENSMUSG00000043432

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
243813

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:243813

UCSC genome browser

More...
UCSCi
uc009exd.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK089196 mRNA Translation: BAC40788.1
AK090365 mRNA Translation: BAC41185.1
AK134559 mRNA Translation: BAE22187.1
AK147019 mRNA Translation: BAE27612.1
AC101941 Genomic DNA No translation available.
BC116676 mRNA Translation: AAI16677.1
CH466627 Genomic DNA Translation: EDL31225.1
CCDSiCCDS20732.1
RefSeqiNP_780738.1, NM_175529.3

3D structure databases

SMRiQ8BTN6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000061079

PTM databases

iPTMnetiQ8BTN6
PhosphoSitePlusiQ8BTN6

Proteomic databases

MaxQBiQ8BTN6
PaxDbiQ8BTN6
PeptideAtlasiQ8BTN6
PRIDEiQ8BTN6

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
72623 72 antibodies

Genome annotation databases

EnsembliENSMUST00000058358; ENSMUSP00000061079; ENSMUSG00000043432
GeneIDi243813
KEGGimmu:243813
UCSCiuc009exd.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
94059
MGIiMGI:2444509 Leng9

Phylogenomic databases

eggNOGiENOG410IWVT Eukaryota
ENOG4111GEQ LUCA
GeneTreeiENSGT00390000010577
HOGENOMiCLU_044135_0_0_1
InParanoidiQ8BTN6
OMAiPTHFICF
OrthoDBi1210602at2759
PhylomeDBiQ8BTN6
TreeFamiTF329287

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
243813 0 hits in 12 CRISPR screens

Protein Ontology

More...
PROi
PR:Q8BTN6
RNActiQ8BTN6 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000043432 Expressed in intestine and 132 other tissues
GenevisibleiQ8BTN6 MM

Family and domain databases

InterProiView protein in InterPro
IPR009097 Cyclic_Pdiesterase
IPR019510 Kinase-A_anchor_nucl_local_sig
IPR042653 Leng9
IPR040459 MJ1316
IPR041367 Znf-CCCH_4
IPR000571 Znf_CCCH
PANTHERiPTHR46729 PTHR46729, 1 hit
PfamiView protein in Pfam
PF10469 AKAP7_NLS, 1 hit
PF04457 MJ1316, 1 hit
PF18044 zf-CCCH_4, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF55144 SSF55144, 1 hit
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLENG9_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BTN6
Secondary accession number(s): Q3UYM5, Q8BTG8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: March 1, 2003
Last modified: June 17, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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