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Protein

Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

Gene

Ankrd52

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Short name:
PP6-ARS-C
Short name:
Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C
Gene namesi
Name:Ankrd52
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2444029 Ankrd52

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002445881 – 1076Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit CAdd BLAST1076

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1028PhosphoserineBy similarity1
Modified residuei1075PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8BTI7
MaxQBiQ8BTI7
PaxDbiQ8BTI7
PeptideAtlasiQ8BTI7
PRIDEiQ8BTI7

PTM databases

iPTMnetiQ8BTI7
PhosphoSitePlusiQ8BTI7

Expressioni

Gene expression databases

BgeeiENSMUSG00000014498
CleanExiMM_ANKRD52
ExpressionAtlasiQ8BTI7 baseline and differential

Interactioni

Subunit structurei

Protein phosphatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6R1 (By similarity).By similarity

Protein-protein interaction databases

IntActiQ8BTI7, 1 interactor
STRINGi10090.ENSMUSP00000014642

Structurei

3D structure databases

ProteinModelPortaliQ8BTI7
SMRiQ8BTI7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati7 – 36ANK 1Add BLAST30
Repeati40 – 69ANK 2Add BLAST30
Repeati73 – 102ANK 3Add BLAST30
Repeati106 – 135ANK 4Add BLAST30
Repeati139 – 168ANK 5Add BLAST30
Repeati172 – 201ANK 6Add BLAST30
Repeati205 – 234ANK 7Add BLAST30
Repeati238 – 267ANK 8Add BLAST30
Repeati271 – 301ANK 9Add BLAST31
Repeati305 – 334ANK 10Add BLAST30
Repeati338 – 367ANK 11Add BLAST30
Repeati371 – 400ANK 12Add BLAST30
Repeati422 – 451ANK 13Add BLAST30
Repeati455 – 484ANK 14Add BLAST30
Repeati488 – 545ANK 15Add BLAST58
Repeati549 – 579ANK 16Add BLAST31
Repeati584 – 613ANK 17Add BLAST30
Repeati617 – 646ANK 18Add BLAST30
Repeati651 – 680ANK 19Add BLAST30
Repeati687 – 716ANK 20Add BLAST30
Repeati720 – 749ANK 21Add BLAST30
Repeati753 – 782ANK 22Add BLAST30
Repeati790 – 819ANK 23Add BLAST30
Repeati822 – 852ANK 24Add BLAST31
Repeati857 – 886ANK 25Add BLAST30
Repeati890 – 920ANK 26Add BLAST31
Repeati924 – 953ANK 27Add BLAST30
Repeati960 – 989ANK 28Add BLAST30

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00840000129677
HOGENOMiHOG000033959
HOVERGENiHBG067697
InParanoidiQ8BTI7
KOiK15504
OMAiKNCGIAA
OrthoDBiEOG091G02S4
PhylomeDBiQ8BTI7
TreeFamiTF312824

Family and domain databases

CDDicd00204 ANK, 8 hits
Gene3Di1.25.40.20, 8 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF00023 Ank, 3 hits
PF12796 Ank_2, 9 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 28 hits
SUPFAMiSSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits

Sequencei

Sequence statusi: Complete.

Q8BTI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGILSITDQP PLVQAIFSRD VEEVRSLLSQ KENINVLDQE RRTPLHAAAY
60 70 80 90 100
VGDVPILQLL LMSGANVNAK DTLWLTPLHR AAASRNEKVL GLLLAHSADV
110 120 130 140 150
NARDKLWQTP LHVAAANRAT KCAEALAPLL SSLNVADRSG RSALHHAVHS
160 170 180 190 200
GHLETVNLLL NKGASLNVCD KKERQPLHWA AFLGHLEVLK LLVARGADLS
210 220 230 240 250
CKDRKGYGLL HTAAASGQIE VVKHLLRMGA EIDEPNAFGN TALHIACYLG
260 270 280 290 300
QDAVAIELVN AGANVNQPND KGFTPLHVAA VSTNGALCLE LLVNNGADVN
310 320 330 340 350
YQSKEGKSPL HMAAIHGRFT RSQILIQNGS EIDCADKFGN TPLHVAARYG
360 370 380 390 400
HELLISTLMT NGADTARRGI HDMFPLHLAV LFGFSDCCRK LLSSGQLYSI
410 420 430 440 450
VSSLSNEHVL SAGFDINTPD SLGRTCLHAA ASGGNVECLN LLLSSGADLR
460 470 480 490 500
RRDKFGRTPL HYAAANGSYQ CAVTLVTAGA GVNEADCKGC SPLHYAAASD
510 520 530 540 550
TYRRAEPHTA SSHDAEEDEL LKESRRKEAF FCLEFLLDNG ADPSLRDRQG
560 570 580 590 600
YTAVHYAAAY GNRQNLELLL EMSFNCLEDV ESTVPVSPLH LAAYNGHCEA
610 620 630 640 650
LKTLAETLVN LDVRDHKGRT ALFLATERGS TECVEVLTAH GASALIKERK
660 670 680 690 700
RKWTPLHAAA ASGHTDSLHL LIDSGERADI TDVMDAYGQT PLMLAIMNGH
710 720 730 740 750
VDCVHLLLEK GSTADAADLR GRTALHRGAV TGCEDCLAAL LDHDAFVLCR
760 770 780 790 800
DFKGRTPIHL ASACGHTAVL RTLLQAALST DPLDAGVDYS GYSPMHWASY
810 820 830 840 850
TGHEDCLELL LEHSPFSYLE GNPFTPLHCA VINNQDSTTE MLLGALGAKI
860 870 880 890 900
VNSRDAKGRT PLHAAAFADN VSGLRMLLQH QAEVNATDHT GRTALMTAAE
910 920 930 940 950
SGQTAAVEFL LYRGKADLTV LDENKNTALH LACSKGHEKC ALMILAETQD
960 970 980 990 1000
LGLINATNSA LQMPLHIAAR NGLASVVQAL LSRGATVLAV DEEGHTPALA
1010 1020 1030 1040 1050
CAPNKDVADC LALILSTMKP FPPKDAVSPF SFSLLKNCGI AAAKTVGGCG
1060 1070
ALPHGASCPY SQERHGAIGL DGCYSE
Length:1,076
Mass (Da):115,032
Last modified:March 1, 2003 - v1
Checksum:i058FE2C95E1A5682
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090124 mRNA Translation: BAC41105.1
BC117907 mRNA Translation: AAI17908.1
BC117908 mRNA Translation: AAI17909.1
CCDSiCCDS24274.1
RefSeqiNP_766378.1, NM_172790.2
UniGeneiMm.440177

Genome annotation databases

EnsembliENSMUST00000014642; ENSMUSP00000014642; ENSMUSG00000014498
GeneIDi237615
KEGGimmu:237615
UCSCiuc007hmm.1 mouse

Similar proteinsi

Entry informationi

Entry nameiANR52_MOUSE
AccessioniPrimary (citable) accession number: Q8BTI7
Secondary accession number(s): Q148Z3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2003
Last modified: February 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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