Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RNA-binding Raly-like protein

Gene

Ralyl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • identical protein binding Source: MGI
  • RNA binding Source: GO_Central

Keywordsi

Molecular functionRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding Raly-like protein
Gene namesi
Name:Ralyl
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1924147 Ralyl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002995261 – 293RNA-binding Raly-like proteinAdd BLAST293

Proteomic databases

PaxDbiQ8BTF8
PeptideAtlasiQ8BTF8
PRIDEiQ8BTF8

PTM databases

iPTMnetiQ8BTF8
PhosphoSitePlusiQ8BTF8

Expressioni

Gene expression databases

BgeeiENSMUSG00000039717 Expressed in 101 organ(s), highest expression level in visual cortex
CleanExiMM_RALYL
ExpressionAtlasiQ8BTF8 baseline and differential
GenevisibleiQ8BTF8 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104009

Structurei

3D structure databases

ProteinModelPortaliQ8BTF8
SMRiQ8BTF8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 92RRMPROSITE-ProRule annotationAdd BLAST72

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili192 – 255Sequence analysisAdd BLAST64

Sequence similaritiesi

Belongs to the RRM HNRPC family. RALY subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IQUK Eukaryota
ENOG410ZKEK LUCA
GeneTreeiENSGT00390000006718
HOGENOMiHOG000231958
HOVERGENiHBG002302
InParanoidiQ8BTF8
OMAiKPYRPKA
OrthoDBiEOG091G0O1Q
PhylomeDBiQ8BTF8
TreeFamiTF330974

Family and domain databases

CDDicd12605 RRM_RALYL, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR017347 hnRNP_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034504 RALYL_RRM
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PIRSFiPIRSF037992 hnRNP-C_Raly, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BTF8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTGKTQTSNI TNKNDPKSIN SRVFIGNLNT AIVKKVDIEA IFSKYGKIVG
60 70 80 90 100
CSVHKGYAFV QYMSERHARA AVAGENARVI AGQPLDINMA GEPKPYRPKP
110 120 130 140 150
GSKRPLSALY RLESKEPFLS VGGYVFDYDY YRDDFYNRLF DYHGRVPPPP
160 170 180 190 200
RAVIPLKRPR VAVTTTRRGK GVFSMKGGSR STVGGSSSSG SKLKSDELQT
210 220 230 240 250
IKKELTQIKT KIDSLLGRLE KIEKQQKAEA EAQKKQLEES IELIQDECVS
260 270 280 290
ENADHSTEEP AEGGQEADGG EMTDGVEEDF DEDGGHELFL QIK
Length:293
Mass (Da):32,452
Last modified:March 1, 2003 - v1
Checksum:iA7FC5C4B1F3A80DF
GO
Isoform 2 (identifier: Q8BTF8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-73: Missing.
     74-86: GENARVIAGQPLD → MTMYRSKRRHQRY

Show »
Length:220
Mass (Da):24,924
Checksum:iDE5B4A9709CDCB94
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A6YXQ8A0A0A6YXQ8_MOUSE
RNA-binding Raly-like protein
Ralyl
164Annotation score:
E9Q5X7E9Q5X7_MOUSE
RNA-binding Raly-like protein
Ralyl
148Annotation score:
A0A1D5RLK6A0A1D5RLK6_MOUSE
RNA-binding Raly-like protein
Ralyl
85Annotation score:
A0A1D5RLM5A0A1D5RLM5_MOUSE
RNA-binding Raly-like protein
Ralyl
163Annotation score:
A0A1D5RMF0A0A1D5RMF0_MOUSE
RNA-binding Raly-like protein
Ralyl
89Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti211K → R in BAC27689 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0277271 – 73Missing in isoform 2. 2 PublicationsAdd BLAST73
Alternative sequenceiVSP_02772874 – 86GENAR…GQPLD → MTMYRSKRRHQRY in isoform 2. 2 PublicationsAdd BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032086 mRNA Translation: BAC27689.1
AK038465 mRNA Translation: BAC30009.1
AK079659 mRNA Translation: BAC37718.1
BC052358 mRNA Translation: AAH52358.1
CCDSiCCDS50863.1 [Q8BTF8-2]
CCDS84609.1 [Q8BTF8-1]
RefSeqiNP_001156800.1, NM_001163328.1 [Q8BTF8-1]
NP_001156801.1, NM_001163329.1 [Q8BTF8-2]
NP_848746.1, NM_178631.4 [Q8BTF8-1]
XP_011246452.1, XM_011248150.2 [Q8BTF8-1]
XP_017175290.1, XM_017319801.1
UniGeneiMm.422625

Genome annotation databases

EnsembliENSMUST00000108372; ENSMUSP00000104009; ENSMUSG00000039717 [Q8BTF8-2]
ENSMUST00000193117; ENSMUSP00000148795; ENSMUSG00000039717 [Q8BTF8-1]
GeneIDi76897
KEGGimmu:76897
UCSCiuc008oqb.2 mouse [Q8BTF8-1]
uc008oqf.2 mouse [Q8BTF8-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032086 mRNA Translation: BAC27689.1
AK038465 mRNA Translation: BAC30009.1
AK079659 mRNA Translation: BAC37718.1
BC052358 mRNA Translation: AAH52358.1
CCDSiCCDS50863.1 [Q8BTF8-2]
CCDS84609.1 [Q8BTF8-1]
RefSeqiNP_001156800.1, NM_001163328.1 [Q8BTF8-1]
NP_001156801.1, NM_001163329.1 [Q8BTF8-2]
NP_848746.1, NM_178631.4 [Q8BTF8-1]
XP_011246452.1, XM_011248150.2 [Q8BTF8-1]
XP_017175290.1, XM_017319801.1
UniGeneiMm.422625

3D structure databases

ProteinModelPortaliQ8BTF8
SMRiQ8BTF8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104009

PTM databases

iPTMnetiQ8BTF8
PhosphoSitePlusiQ8BTF8

Proteomic databases

PaxDbiQ8BTF8
PeptideAtlasiQ8BTF8
PRIDEiQ8BTF8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000108372; ENSMUSP00000104009; ENSMUSG00000039717 [Q8BTF8-2]
ENSMUST00000193117; ENSMUSP00000148795; ENSMUSG00000039717 [Q8BTF8-1]
GeneIDi76897
KEGGimmu:76897
UCSCiuc008oqb.2 mouse [Q8BTF8-1]
uc008oqf.2 mouse [Q8BTF8-2]

Organism-specific databases

CTDi138046
MGIiMGI:1924147 Ralyl

Phylogenomic databases

eggNOGiENOG410IQUK Eukaryota
ENOG410ZKEK LUCA
GeneTreeiENSGT00390000006718
HOGENOMiHOG000231958
HOVERGENiHBG002302
InParanoidiQ8BTF8
OMAiKPYRPKA
OrthoDBiEOG091G0O1Q
PhylomeDBiQ8BTF8
TreeFamiTF330974

Miscellaneous databases

PROiPR:Q8BTF8
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039717 Expressed in 101 organ(s), highest expression level in visual cortex
CleanExiMM_RALYL
ExpressionAtlasiQ8BTF8 baseline and differential
GenevisibleiQ8BTF8 MM

Family and domain databases

CDDicd12605 RRM_RALYL, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR017347 hnRNP_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034504 RALYL_RRM
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PIRSFiPIRSF037992 hnRNP-C_Raly, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRALYL_MOUSE
AccessioniPrimary (citable) accession number: Q8BTF8
Secondary accession number(s): Q8BTF9, Q8BTG1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again