UniProtKB - Q8BSQ9 (PB1_MOUSE)
Protein polybromo-1
Pbrm1
Functioni
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.
2 PublicationsBy similarityRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 1379 – 1447 | HMG boxPROSITE-ProRule annotationAdd BLAST | 69 |
GO - Molecular functioni
- chromatin binding Source: MGI
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- blastocyst formation Source: MGI
- blood vessel remodeling Source: DFLAT
- cardiac vascular smooth muscle cell development Source: DFLAT
- chromatin remodeling Source: ComplexPortal
- epicardium-derived cardiac endothelial cell differentiation Source: DFLAT
- heart development Source: MGI
- heart morphogenesis Source: DFLAT
- negative regulation of cell population proliferation Source: UniProtKB
- placenta development Source: MGI
- positive regulation of cell differentiation Source: ComplexPortal
- positive regulation of dendritic spine development Source: MGI
- positive regulation of double-strand break repair Source: ComplexPortal
- positive regulation of myoblast differentiation Source: ComplexPortal
- positive regulation of T cell differentiation Source: ComplexPortal
- positive regulation of transcription, DNA-templated Source: DFLAT
- regulation of G0 to G1 transition Source: ComplexPortal
- regulation of G1/S transition of mitotic cell cycle Source: ComplexPortal
- regulation of mitotic metaphase/anaphase transition Source: ComplexPortal
- regulation of nucleotide-excision repair Source: ComplexPortal
- regulation of transcription by RNA polymerase II Source: ComplexPortal
- vasculogenesis involved in coronary vascular morphogenesis Source: DFLAT
Keywordsi
Molecular function | Chromatin regulator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
Reactomei | R-MMU-3214858, RMTs methylate histone arginines R-MMU-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
Names & Taxonomyi
Protein namesi | Recommended name: Protein polybromo-1Alternative name(s): BRG1-associated factor 180 Short name: BAF180 |
Gene namesi | Name:Pbrm1 Synonyms:Baf180, Pb1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1923998, Pbrm1 |
VEuPathDBi | HostDB:ENSMUSG00000042323 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nuclear matrix Source: ComplexPortal
- nucleoplasm Source: MGI
- nucleus Source: MGI
- RSC-type complex Source: GO_Central
- SWI/SNF complex Source: MGI
Other locations
- chromatin Source: ComplexPortal
- kinetochore Source: MGI
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000351134 | 1 – 1634 | Protein polybromo-1Add BLAST | 1634 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 10 | PhosphoserineBy similarity | 1 | |
Modified residuei | 39 | PhosphoserineCombined sources | 1 | |
Cross-linki | 96 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 131 | PhosphoserineBy similarity | 1 | |
Modified residuei | 134 | PhosphotyrosineBy similarity | 1 | |
Cross-linki | 154 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 178 | PhosphoserineBy similarity | 1 | |
Cross-linki | 210 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 319 | PhosphoserineBy similarity | 1 | |
Modified residuei | 353 | PhosphoserineCombined sources | 1 | |
Modified residuei | 355 | PhosphoserineCombined sources | 1 | |
Modified residuei | 371 | PhosphoserineBy similarity | 1 | |
Modified residuei | 375 | PhosphoserineBy similarity | 1 | |
Modified residuei | 414 | N6-acetyllysineCombined sources | 1 | |
Cross-linki | 425 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 471 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 498 | PhosphoserineCombined sources | 1 | |
Modified residuei | 509 | PhosphoserineBy similarity | 1 | |
Cross-linki | 511 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 591 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 636 | PhosphoserineCombined sources | 1 | |
Cross-linki | 638 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 648 | PhosphoserineBy similarity | 1 | |
Cross-linki | 653 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 689 | PhosphoserineBy similarity | 1 | |
Modified residuei | 948 | PhosphoserineBy similarity | 1 | |
Modified residuei | 987 | PhosphoserineBy similarity | 1 | |
Cross-linki | 1106 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 1111 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 1167 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 1289 | PhosphotyrosineCombined sources | 1 | |
Cross-linki | 1293 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity | ||
Cross-linki | 1293 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity | ||
Cross-linki | 1308 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 1398 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 1405 | PhosphoserineBy similarity | 1 | |
Cross-linki | 1587 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 1599 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 1601 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q8BSQ9 |
jPOSTi | Q8BSQ9 |
MaxQBi | Q8BSQ9 |
PaxDbi | Q8BSQ9 |
PeptideAtlasi | Q8BSQ9 |
PRIDEi | Q8BSQ9 |
ProteomicsDBi | 294334 [Q8BSQ9-1] 294335 [Q8BSQ9-2] |
PTM databases
iPTMneti | Q8BSQ9 |
PhosphoSitePlusi | Q8BSQ9 |
Expressioni
Developmental stagei
Gene expression databases
Bgeei | ENSMUSG00000042323, Expressed in blood and 321 other tissues |
ExpressionAtlasi | Q8BSQ9, baseline and differential |
Genevisiblei | Q8BSQ9, MM |
Interactioni
Subunit structurei
Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47/SNF5, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PBRM1/BAF180, ARID2/BAF200 and actin.
Interacts with PHF10/BAF45A (By similarity).
Interacts with acetylated 'Lys-14' of histone H3 (H3K14ac), and may also interact with other acetylated or methylated Lys residues on histone H3 (By similarity).
2 PublicationsBy similarity1 PublicationProtein-protein interaction databases
ComplexPortali | CPX-1248, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A variant CPX-1250, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B variant |
DIPi | DIP-48885N |
IntActi | Q8BSQ9, 6 interactors |
MINTi | Q8BSQ9 |
STRINGi | 10090.ENSMUSP00000107727 |
Miscellaneous databases
RNActi | Q8BSQ9, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q8BSQ9 |
SMRi | Q8BSQ9 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q8BSQ9 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 64 – 134 | Bromo 1PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 200 – 270 | Bromo 2PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 400 – 470 | Bromo 3PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 538 – 608 | Bromo 4PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 676 – 746 | Bromo 5PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 792 – 862 | Bromo 6PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 956 – 1074 | BAH 1PROSITE-ProRule annotationAdd BLAST | 119 | |
Domaini | 1156 – 1272 | BAH 2PROSITE-ProRule annotationAdd BLAST | 117 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 155 – 179 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 487 – 517 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 625 – 653 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 901 – 942 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 1106 – 1129 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 1354 – 1378 | DisorderedSequence analysisAdd BLAST | 25 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 19 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 625 – 639 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 901 – 933 | Basic and acidic residuesSequence analysisAdd BLAST | 33 |
Keywords - Domaini
Bromodomain, RepeatPhylogenomic databases
eggNOGi | KOG1827, Eukaryota |
GeneTreei | ENSGT00390000003017 |
InParanoidi | Q8BSQ9 |
Family and domain databases
CDDi | cd05515, Bromo_polybromo_V, 1 hit |
Gene3Di | 1.20.920.10, 6 hits 2.30.30.490, 2 hits |
InterProi | View protein in InterPro IPR001025, BAH_dom IPR043151, BAH_sf IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf IPR037968, PBRM1_BD5 IPR037382, Rsc/polybromo |
PANTHERi | PTHR16062, PTHR16062, 2 hits |
Pfami | View protein in Pfam PF01426, BAH, 2 hits PF00439, Bromodomain, 6 hits PF00505, HMG_box, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00439, BAH, 2 hits SM00297, BROMO, 6 hits SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit SSF47370, SSF47370, 6 hits |
PROSITEi | View protein in PROSITE PS51038, BAH, 2 hits PS00633, BROMODOMAIN_1, 5 hits PS50014, BROMODOMAIN_2, 6 hits PS50118, HMG_BOX_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 13 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGSKRRRATS PSSSVSGDFD DGHHSVPTPG PSRKRRRLSN LPTVDPIAVC
60 70 80 90 100
HELYNTIRDY KDEQGRLLCE LFIRAPKRRN QPDYYEVVSQ PIDLMKIQQK
110 120 130 140 150
LKMEEYDDVN LLTADFQLLF NNAKAYYKPD SPEYKAACKL WDLYLRTRNE
160 170 180 190 200
FVQKGEADDE DDDEDGQDNQ GTLADGSSPG YLKEILEQLL EAIVVATNPS
210 220 230 240 250
GRLISELFQK LPSKVQYPDY YAIIKEPIDL KTIAQRIQNG SYKSIHAMAK
260 270 280 290 300
DIDLLAKNAK TYNEPGSQVF KDANSIKKIF YMKKAEIEHH EMTKSSLRIR
310 320 330 340 350
TASNLAAARL TGPSHNKSSL GEERNPTSKY YRNKRAVQGG RLSAITMALQ
360 370 380 390 400
YGSESEEDAA LAAARYEEGE SEAESITSFM DVSNPFHQLY DTVRSCRNHQ
410 420 430 440 450
GQLIAEPFFH LPSKKKYPDY YQQIKMPISL QQIRTKLKNQ EYETLDHLEC
460 470 480 490 500
DLNLMFENAK RYNVPNSAIY KRVLKLQQVM QAKKKELARR DDIEDGDSMI
510 520 530 540 550
SSATSDTGSA KRKSKKNIRK QRMKILFNVV LEAREPGSGR RLCDLFMVKP
560 570 580 590 600
SKKDYPDYYK IILEPMDLKI IEHNIRNDKY AGEEGMMEDM KLMFRNARHY
610 620 630 640 650
NEEGSQVYND AHILEKLLKD KRKELGPLPD DDDMASPKLK LSRKSGVSPK
660 670 680 690 700
KSKYMTPMQQ KLNEVYEAVK NYTDKRGRRL SAIFLRLPSR SELPDYYLTI
710 720 730 740 750
KKPMDMEKIR SHMMANKYQD IDSMVEDFVM MFNNACTYNE PESLIYKDAL
760 770 780 790 800
VLHKVLLETR RDLEGDEDSH VPNVTLLIQE LIHNLFVSVM SHQDDEGRCY
810 820 830 840 850
SDSLAEIPAV DPNSPNKPPL TFDIIRKNVE SNRYRRLDLF QEHMFEVLER
860 870 880 890 900
ARRMNRTDSE IYEDAVELQQ FFIRIRDELC KNGEILLSPA LSYTTKHLHN
910 920 930 940 950
DVEKEKKEKL PKEIEEDKLK REEEKREAEK SEDSSGTTGL SGLHRTYSQD
960 970 980 990 1000
CSFKNSMYHV GDYVYVEPAE ANLQPHIVCI ERLWEDSAGE KWLYGCWFYR
1010 1020 1030 1040 1050
PNETFHLATR KFLEKEVFKS DYYNKVPVSK ILGKCVVMFV KEYFKLCPEN
1060 1070 1080 1090 1100
FRDEDVFVCE SRYSAKTKSF KKIKLWTMPI SSVRFVPRDV PLPVVRVASV
1110 1120 1130 1140 1150
FANADKGDDE KNTDNSDDNR AEDNFNLEKE KEDVPVEMSN GEPGCHYFEQ
1160 1170 1180 1190 1200
LRYNDMWLKV GDCVFIKSHG LVRPRVGRIE KVWVRDGAAY FYGPIFIHPE
1210 1220 1230 1240 1250
ETEHEPTKMF YKKEVFLSNL EETCPMSCIL GKCAVLSFKD FLSCRPTEIP
1260 1270 1280 1290 1300
ENDILLCESR YNESDKQMKK FKGLKRFSLS AKVVDDEIYY FRKPIIPQKE
1310 1320 1330 1340 1350
PSPLLEKKIQ LLEAKFAELE GGDDDIEEMG EEDSEVIEAP SLPQLQTPLA
1360 1370 1380 1390 1400
NELDLMPYTP PQSTPKSAKG SAKKESSKRK INMSGYILFS SEMRAVIKAQ
1410 1420 1430 1440 1450
HPDYSFGELS RLVGTEWRNL ETAKKAEYEG MMGGYPPGLP PLQGPVDGLV
1460 1470 1480 1490 1500
SMGSMQPLHP GGPPPHHLPP GVPGLPGIPP PGVMNQGVAP MVGTPAPGGS
1510 1520 1530 1540 1550
PYGQQVGVLG PPGQQAPPPY PGPHPAGPPV IQQPTTPMFV APPPKTQRLL
1560 1570 1580 1590 1600
HSEAYLKYIE GLSAESNSIS KWDQTLAARR RDVHLSKEQE SRLPSHWLKS
1610 1620 1630
KGAHTTMADA LWRLRDLMLR DTLNIRQAYN LENV
Computationally mapped potential isoform sequencesi
There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF8VQD1 | F8VQD1_MOUSE | Protein polybromo-1 | Pbrm1 | 1,704 | Annotation score: | ||
D3Z1N4 | D3Z1N4_MOUSE | Protein polybromo-1 | Pbrm1 | 1,652 | Annotation score: | ||
D3YYF2 | D3YYF2_MOUSE | Protein polybromo-1 | Pbrm1 | 1,460 | Annotation score: | ||
D3Z1W6 | D3Z1W6_MOUSE | Protein polybromo-1 | Pbrm1 | 1,582 | Annotation score: | ||
E9Q7L2 | E9Q7L2_MOUSE | Protein polybromo-1 | Pbrm1 | 1,597 | Annotation score: | ||
E9Q7L3 | E9Q7L3_MOUSE | Protein polybromo-1 | Pbrm1 | 1,582 | Annotation score: | ||
E9Q4Y5 | E9Q4Y5_MOUSE | Protein polybromo-1 | Pbrm1 | 1,689 | Annotation score: | ||
F6THL5 | F6THL5_MOUSE | Protein polybromo-1 | Pbrm1 | 1,085 | Annotation score: | ||
D3Z3R4 | D3Z3R4_MOUSE | Protein polybromo-1 | Pbrm1 | 931 | Annotation score: | ||
D6RI94 | D6RI94_MOUSE | Protein polybromo-1 | Pbrm1 | 860 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 417 | Y → K in AAH23452 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 695 | D → E in BAC27136 (PubMed:16141072).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_035471 | 300 – 332 | RTASN…SKYYR → S in isoform 2. 2 PublicationsAdd BLAST | 33 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC154446 Genomic DNA No translation available. AC154727 Genomic DNA No translation available. BC023452 mRNA Translation: AAH23452.1 BC029037 mRNA Translation: AAH29037.1 Different termination. BC055456 mRNA Translation: AAH55456.1 Different termination. BC055708 mRNA Translation: AAH55708.1 Different initiation. BF451491 mRNA No translation available. CN530699 mRNA No translation available. AK009582 mRNA Translation: BAB26374.2 AK030781 mRNA Translation: BAC27136.2 AK030252 mRNA No translation available. AK166588 mRNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000112094; ENSMUSP00000107723; ENSMUSG00000042323 [Q8BSQ9-2] ENSMUST00000112095; ENSMUSP00000107724; ENSMUSG00000042323 [Q8BSQ9-1] |
UCSCi | uc007swl.1, mouse [Q8BSQ9-1] uc007swm.1, mouse [Q8BSQ9-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC154446 Genomic DNA No translation available. AC154727 Genomic DNA No translation available. BC023452 mRNA Translation: AAH23452.1 BC029037 mRNA Translation: AAH29037.1 Different termination. BC055456 mRNA Translation: AAH55456.1 Different termination. BC055708 mRNA Translation: AAH55708.1 Different initiation. BF451491 mRNA No translation available. CN530699 mRNA No translation available. AK009582 mRNA Translation: BAB26374.2 AK030781 mRNA Translation: BAC27136.2 AK030252 mRNA No translation available. AK166588 mRNA No translation available. |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2YQD | NMR | - | A | 650-762 | [»] | |
AlphaFoldDBi | Q8BSQ9 | |||||
SMRi | Q8BSQ9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
ComplexPortali | CPX-1248, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A variant CPX-1250, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B variant |
DIPi | DIP-48885N |
IntActi | Q8BSQ9, 6 interactors |
MINTi | Q8BSQ9 |
STRINGi | 10090.ENSMUSP00000107727 |
PTM databases
iPTMneti | Q8BSQ9 |
PhosphoSitePlusi | Q8BSQ9 |
Proteomic databases
EPDi | Q8BSQ9 |
jPOSTi | Q8BSQ9 |
MaxQBi | Q8BSQ9 |
PaxDbi | Q8BSQ9 |
PeptideAtlasi | Q8BSQ9 |
PRIDEi | Q8BSQ9 |
ProteomicsDBi | 294334 [Q8BSQ9-1] 294335 [Q8BSQ9-2] |
Protocols and materials databases
Antibodypediai | 2905, 176 antibodies from 29 providers |
Genome annotation databases
Ensembli | ENSMUST00000112094; ENSMUSP00000107723; ENSMUSG00000042323 [Q8BSQ9-2] ENSMUST00000112095; ENSMUSP00000107724; ENSMUSG00000042323 [Q8BSQ9-1] |
UCSCi | uc007swl.1, mouse [Q8BSQ9-1] uc007swm.1, mouse [Q8BSQ9-2] |
Organism-specific databases
MGIi | MGI:1923998, Pbrm1 |
VEuPathDBi | HostDB:ENSMUSG00000042323 |
Phylogenomic databases
eggNOGi | KOG1827, Eukaryota |
GeneTreei | ENSGT00390000003017 |
InParanoidi | Q8BSQ9 |
Enzyme and pathway databases
Reactomei | R-MMU-3214858, RMTs methylate histone arginines R-MMU-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
Miscellaneous databases
ChiTaRSi | Pbrm1, mouse |
EvolutionaryTracei | Q8BSQ9 |
PROi | PR:Q8BSQ9 |
RNActi | Q8BSQ9, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000042323, Expressed in blood and 321 other tissues |
ExpressionAtlasi | Q8BSQ9, baseline and differential |
Genevisiblei | Q8BSQ9, MM |
Family and domain databases
CDDi | cd05515, Bromo_polybromo_V, 1 hit |
Gene3Di | 1.20.920.10, 6 hits 2.30.30.490, 2 hits |
InterProi | View protein in InterPro IPR001025, BAH_dom IPR043151, BAH_sf IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf IPR037968, PBRM1_BD5 IPR037382, Rsc/polybromo |
PANTHERi | PTHR16062, PTHR16062, 2 hits |
Pfami | View protein in Pfam PF01426, BAH, 2 hits PF00439, Bromodomain, 6 hits PF00505, HMG_box, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00439, BAH, 2 hits SM00297, BROMO, 6 hits SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit SSF47370, SSF47370, 6 hits |
PROSITEi | View protein in PROSITE PS51038, BAH, 2 hits PS00633, BROMODOMAIN_1, 5 hits PS50014, BROMODOMAIN_2, 6 hits PS50118, HMG_BOX_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PB1_MOUSE | |
Accessioni | Q8BSQ9Primary (citable) accession number: Q8BSQ9 Secondary accession number(s): E9QPW1 Q9CV51 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 23, 2008 |
Last sequence update: | July 27, 2011 | |
Last modified: | May 25, 2022 | |
This is version 146 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references