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Protein
Submitted name:

CLIP-associating protein 2

Gene

Clasp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Submitted name:
CLIP-associating protein 2Imported
Gene namesi
Name:Clasp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1923749 Clasp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 232TOGInterPro annotationAdd BLAST226
Repeati168 – 206HEATPROSITE-ProRule annotationAdd BLAST39

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762
HOGENOMiHOG000147799

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR028399 CLASP_1
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG
PANTHERiPTHR21567:SF28 PTHR21567:SF28, 1 hit
PfamiView protein in Pfam
PF12348 CLASP_N, 1 hit
SMARTiView protein in SMART
SM01349 TOG, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.iShow all

Q8BSE7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPRGAEYFC AQVLQKDVSG RLQAGEELLL CLGTPGAIPD LEDDPSRLAK
60 70 80 90 100
TVDALTRWVG SSNYRVSLLG LEILSAFVDR LSTRFKSYVT MVTTALIDRM
110 120 130 140 150
GDVKDKVREE AQNLTLKLMD EVAPPMYIWE QLASGFKHKN FRSREGVCLC
160 170 180 190 200
LIETLNIFGT QPLVISKLVP HLCVLFGDSN SQVRNAALSA VVEIYRHVGE
210 220 230 240 250
KLRIDLCKRD IPPARLEMVL AKFDEVQNSG GMILSVCKDK SFDDEESVDG
260 270 280 290 300
NRPSSAASAF KVPAPKTPGN PVSSARKPGS AGGPKVGGPS KEGGAGAVDE
310 320 330 340 350
DDFIKAFTDV PSVQIYSSRE LEETLNKIRE ILSDDKHDWD QRANACMSCS
360 370 380 390 400
LVASEVERAL AWPLWSHLAT YQHHCHCTLS HEDLPEKRLT SPVSSAFVQH
Length:400
Mass (Da):44,014
Last modified:March 1, 2003 - v1
Checksum:iC89E859496681E26
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8BRT1CLAP2_MOUSE
CLIP-associating protein 2
Clasp2 Kiaa0627
1,286Annotation score:
A0A1L1ST22A0A1L1ST22_MOUSE
CLIP-associating protein 2
Clasp2
600Annotation score:
Q08EB6Q08EB6_MOUSE
CLIP-associating protein 2
Clasp2
1,287Annotation score:
E9Q8N5E9Q8N5_MOUSE
CLIP-associating protein 2
Clasp2
1,286Annotation score:
F7DCH5F7DCH5_MOUSE
CLIP-associating protein 2
Clasp2
1,307Annotation score:
Q08EB5Q08EB5_MOUSE
CLIP-associating protein 2
Clasp2
1,304Annotation score:
A0A1L1SRY3A0A1L1SRY3_MOUSE
CLIP-associating protein 2
Clasp2
103Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107803 Genomic DNA No translation available.
AC167246 Genomic DNA No translation available.
AK034560 mRNA Translation: BAC28754.1
RefSeqiNP_001273528.1, NM_001286599.1
UniGeneiMm.222272

Genome annotation databases

EnsembliENSMUST00000216817; ENSMUSP00000150741; ENSMUSG00000033392
GeneIDi76499
UCSCiuc009rwq.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107803 Genomic DNA No translation available.
AC167246 Genomic DNA No translation available.
AK034560 mRNA Translation: BAC28754.1
RefSeqiNP_001273528.1, NM_001286599.1
UniGeneiMm.222272

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000216817; ENSMUSP00000150741; ENSMUSG00000033392
GeneIDi76499
UCSCiuc009rwq.1 mouse

Organism-specific databases

CTDi23122
MGIiMGI:1923749 Clasp2

Phylogenomic databases

eggNOGiKOG2956 Eukaryota
ENOG410ZMY0 LUCA
GeneTreeiENSGT00390000001762
HOGENOMiHOG000147799

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR028399 CLASP_1
IPR024395 CLASP_N_dom
IPR021133 HEAT_type_2
IPR034085 TOG
PANTHERiPTHR21567:SF28 PTHR21567:SF28, 1 hit
PfamiView protein in Pfam
PF12348 CLASP_N, 1 hit
SMARTiView protein in SMART
SM01349 TOG, 1 hit
SUPFAMiSSF48371 SSF48371, 2 hits
PROSITEiView protein in PROSITE
PS50077 HEAT_REPEAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BSE7_MOUSE
AccessioniPrimary (citable) accession number: Q8BSE7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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