Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM214B

Gene

Fam214b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM214B
Gene namesi
Name:Fam214b
Synonyms:Kiaa1539
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2441854 Fam214b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003136221 – 538Protein FAM214BAdd BLAST538

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei254PhosphoserineCombined sources1
Modified residuei255PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8BR27
PRIDEiQ8BR27

PTM databases

iPTMnetiQ8BR27
PhosphoSitePlusiQ8BR27

Expressioni

Gene expression databases

BgeeiENSMUSG00000036002 Expressed in 247 organ(s), highest expression level in blood
CleanExiMM_B230312A22RIK
ExpressionAtlasiQ8BR27 baseline and differential
GenevisibleiQ8BR27 MM

Structurei

3D structure databases

ProteinModelPortaliQ8BR27
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM214 family.Curated

Phylogenomic databases

eggNOGiKOG2306 Eukaryota
ENOG41115V6 LUCA
GeneTreeiENSGT00530000063568
HOGENOMiHOG000049082
HOVERGENiHBG097397
InParanoidiQ8BR27
OMAiGPRELKR
OrthoDBiEOG091G09N8
PhylomeDBiQ8BR27
TreeFamiTF325496

Family and domain databases

InterProiView protein in InterPro
IPR025261 DUF4210
IPR033473 FAM214/SPAC3H8.04_C
PfamiView protein in Pfam
PF13889 Chromosome_seg, 1 hit
PF13915 DUF4210, 1 hit
SMARTiView protein in SMART
SM01177 DUF4210, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8BR27-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRHVQAELSP SSEPEAGPSQ PPVRQGTLQG GLLMGYSPAG GATSPGVYQV
60 70 80 90 100
SIFSPSAGAS EPPRALKRPA PPTEGPRELK RGPGLGAREG LPPEEPSTVG
110 120 130 140 150
LLSPEGLGLG LGVASQHFSH HGLCVVEHGG NTTSPWTSGT QSTPWLSSNA
160 170 180 190 200
SFNTLHTRDW AFPDQGGQGC LGETPGPAPS GQLHTLDTDL HNLAQIGGKS
210 220 230 240 250
PVARVGNGSN PWPRESHGTA NGHSPEHTPP GPGPPGPCPT KRRLLPAGET
260 270 280 290 300
LDVSSEDEGP APRRRRGTLG CPLAANSSDA KATPFWSHLL PGPKEPVLDP
310 320 330 340 350
TDCSPMGRRL KGARRLKLSS LRTLRKGPGL LSPPSASPFP TPAVSRTLLG
360 370 380 390 400
NFEESLLRGR FAPSGHIEGF TAEIGASGSY CPQHVTLPVT VTFFDVSEQN
410 420 430 440 450
APAPFLGVVD LTPLGRKGYS VPKVGTIQVT LFNPNQTVVK MFLVTFDFSD
460 470 480 490 500
MPAAHMTFLR HRLFLVPVGE EGNASPTHRL LCYLLHLRFR SSRSGRLSLH
510 520 530
GDIRLLFSRR SLELDTGLPY ELQAVTEAPH NPRYSPLP
Length:538
Mass (Da):57,075
Last modified:March 1, 2003 - v1
Checksum:iC5D99B108487A580
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q9G4E9Q9G4_MOUSE
Protein FAM214B
Fam214b B230312A22Rik
332Annotation score:
B0QZW7B0QZW7_MOUSE
Protein FAM214B
Fam214b B230312A22Rik
43Annotation score:
S4R159S4R159_MOUSE
Protein FAM214B
Fam214b
137Annotation score:
A0A0G2JDA3A0A0G2JDA3_MOUSE
Protein FAM214B
Fam214b
9Annotation score:

Sequence cautioni

The sequence CAQ12875 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti57A → T in BAE36360 (PubMed:16141072).Curated1
Sequence conflicti241Missing in CAQ12875 (PubMed:19468303).Curated1
Sequence conflicti261A → P in AAH71191 (PubMed:15489334).Curated1
Sequence conflicti325R → G in BAE28988 (PubMed:16141072).Curated1
Sequence conflicti515D → G in BAE32803 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045811 mRNA Translation: BAC32500.1
AK149610 mRNA Translation: BAE28988.1
AK154748 mRNA Translation: BAE32803.1
AK161380 mRNA Translation: BAE36360.1
AL672276 Genomic DNA Translation: CAM14325.1
AL672276 Genomic DNA Translation: CAQ12875.1 Sequence problems.
BC046771 mRNA Translation: AAH46771.1
BC071191 mRNA Translation: AAH71191.1
AK173197 mRNA Translation: BAD32475.1
CCDSiCCDS18090.1
RefSeqiNP_001240282.1, NM_001253353.1
NP_001240283.1, NM_001253354.1
NP_766279.1, NM_172691.3
XP_006537885.1, XM_006537822.2
XP_006537886.1, XM_006537823.3
XP_006537887.1, XM_006537824.1
XP_011248296.1, XM_011249994.1
XP_017175614.1, XM_017320125.1
UniGeneiMm.260162
Mm.490022

Genome annotation databases

EnsembliENSMUST00000036462; ENSMUSP00000038177; ENSMUSG00000036002
ENSMUST00000107956; ENSMUSP00000103590; ENSMUSG00000036002
ENSMUST00000107957; ENSMUSP00000103591; ENSMUSG00000036002
ENSMUST00000107958; ENSMUSP00000103592; ENSMUSG00000036002
ENSMUST00000107959; ENSMUSP00000103593; ENSMUSG00000036002
GeneIDi230088
KEGGimmu:230088
UCSCiuc008soz.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK045811 mRNA Translation: BAC32500.1
AK149610 mRNA Translation: BAE28988.1
AK154748 mRNA Translation: BAE32803.1
AK161380 mRNA Translation: BAE36360.1
AL672276 Genomic DNA Translation: CAM14325.1
AL672276 Genomic DNA Translation: CAQ12875.1 Sequence problems.
BC046771 mRNA Translation: AAH46771.1
BC071191 mRNA Translation: AAH71191.1
AK173197 mRNA Translation: BAD32475.1
CCDSiCCDS18090.1
RefSeqiNP_001240282.1, NM_001253353.1
NP_001240283.1, NM_001253354.1
NP_766279.1, NM_172691.3
XP_006537885.1, XM_006537822.2
XP_006537886.1, XM_006537823.3
XP_006537887.1, XM_006537824.1
XP_011248296.1, XM_011249994.1
XP_017175614.1, XM_017320125.1
UniGeneiMm.260162
Mm.490022

3D structure databases

ProteinModelPortaliQ8BR27
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ8BR27
PhosphoSitePlusiQ8BR27

Proteomic databases

PaxDbiQ8BR27
PRIDEiQ8BR27

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000036462; ENSMUSP00000038177; ENSMUSG00000036002
ENSMUST00000107956; ENSMUSP00000103590; ENSMUSG00000036002
ENSMUST00000107957; ENSMUSP00000103591; ENSMUSG00000036002
ENSMUST00000107958; ENSMUSP00000103592; ENSMUSG00000036002
ENSMUST00000107959; ENSMUSP00000103593; ENSMUSG00000036002
GeneIDi230088
KEGGimmu:230088
UCSCiuc008soz.2 mouse

Organism-specific databases

CTDi80256
MGIiMGI:2441854 Fam214b
RougeiSearch...

Phylogenomic databases

eggNOGiKOG2306 Eukaryota
ENOG41115V6 LUCA
GeneTreeiENSGT00530000063568
HOGENOMiHOG000049082
HOVERGENiHBG097397
InParanoidiQ8BR27
OMAiGPRELKR
OrthoDBiEOG091G09N8
PhylomeDBiQ8BR27
TreeFamiTF325496

Miscellaneous databases

ChiTaRSiFam214b mouse
PROiPR:Q8BR27
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000036002 Expressed in 247 organ(s), highest expression level in blood
CleanExiMM_B230312A22RIK
ExpressionAtlasiQ8BR27 baseline and differential
GenevisibleiQ8BR27 MM

Family and domain databases

InterProiView protein in InterPro
IPR025261 DUF4210
IPR033473 FAM214/SPAC3H8.04_C
PfamiView protein in Pfam
PF13889 Chromosome_seg, 1 hit
PF13915 DUF4210, 1 hit
SMARTiView protein in SMART
SM01177 DUF4210, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF214B_MOUSE
AccessioniPrimary (citable) accession number: Q8BR27
Secondary accession number(s): B0QZW6
, Q3TTG5, Q3U3I3, Q3UEC3, Q69ZG9, Q6IR39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again