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Protein
Submitted name:

MCG20377, isoform CRA_b

Gene

Prl3d1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-1170546 Prolactin receptor signaling
R-MMU-982772 Growth hormone receptor signaling

Names & Taxonomyi

Protein namesi
Submitted name:
MCG20377, isoform CRA_bImported
Submitted name:
Prolactin-3D1Imported
Gene namesi
Name:Prl3d1Imported
Synonyms:Csh1Imported
ORF Names:mCG_20377Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:97606 Prl3d1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_501509904430 – 223Sequence analysisAdd BLAST194

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000057170 Expressed in 13 organ(s), highest expression level in placenta

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00730000110805
HOVERGENiHBG104895
OrthoDBiEOG091G0NUL

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR001400 Somatotropin/Prolactin
IPR018116 Somatotropin_CS
PANTHERiPTHR11417 PTHR11417, 1 hit
PfamiView protein in Pfam
PF00103 Hormone_1, 1 hit
PRINTSiPR00836 SOMATOTROPIN
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00266 SOMATOTROPIN_1, 1 hit
PS00338 SOMATOTROPIN_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q8BNL4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQLTLNLSGS GMQLLLLVSS LLLWENVSSK PTAMVPTEDL YTRLAELSHN
60 70 80 90 100
TFILAADVYR EFDLDFFDKT WITDRTLPLC HTASIHTPEN REEVHETKTE
110 120 130 140 150
DLLKAMINVS ISWKEPLKHL VSALTALPGA SESMGKKAAD IKGRNLVILE
160 170 180 190 200
GLQTIYNRTQ ANIEENENFD YPAWSGLEEL QSPNEDTHLF AVYNLCRCIK
210 220
RDIHKIDSYI KVLRCRVVFQ NEC
Length:223
Mass (Da):25,441
Last modified:March 1, 2003 - v1
Checksum:i9FB4B55A283EF55F
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P18121PR3D1_MOUSE
Prolactin-3D1
Prl3d1 Csh1, Pl-1, Pl1
224Annotation score:
A0A286YC78A0A286YC78_MOUSE
Growth hormone d4
Prl3d1 Ghd4, mCG_20377
224Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591843 Genomic DNA No translation available.
AK082929 mRNA Translation: BAC38697.1
CH466561 Genomic DNA Translation: EDL32451.1
RefSeqiNP_032890.2, NM_008864.3
UniGeneiMm.233151

Genome annotation databases

EnsembliENSMUST00000082079; ENSMUSP00000080731; ENSMUSG00000057170
GeneIDi18775
UCSCiuc007pxd.2 mouse
uc007pxe.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ8BNL4_MOUSE
AccessioniPrimary (citable) accession number: Q8BNL4
Secondary accession number(s): Q5SY42
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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