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Protein

Integrator complex subunit 6-like

Gene

Ints6l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Integrator complex subunit 6-like
Alternative name(s):
Protein DDX26B
Gene namesi
Name:Ints6l
Synonyms:Ddx26b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:2442593 Ints6l

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000762161 – 861Integrator complex subunit 6-likeAdd BLAST861

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei617PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8BND4
MaxQBiQ8BND4
PaxDbiQ8BND4
PeptideAtlasiQ8BND4
PRIDEiQ8BND4

PTM databases

iPTMnetiQ8BND4
PhosphoSitePlusiQ8BND4

Expressioni

Gene expression databases

BgeeiENSMUSG00000035967 Expressed in 261 organ(s), highest expression level in pituitary gland
CleanExiMM_DDX26B
ExpressionAtlasiQ8BND4 baseline and differential
GenevisibleiQ8BND4 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035379

Structurei

3D structure databases

ProteinModelPortaliQ8BND4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 227VWFAPROSITE-ProRule annotationAdd BLAST225

Phylogenomic databases

eggNOGiKOG3768 Eukaryota
ENOG410XRER LUCA
GeneTreeiENSGT00390000016655
HOGENOMiHOG000015308
HOVERGENiHBG081468
InParanoidiQ8BND4
KOiK13180
OMAiGMSLTHN
OrthoDBiEOG091G03YA
PhylomeDBiQ8BND4
TreeFamiTF323386

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit
PF13519 VWA_2, 1 hit
SUPFAMiSSF53300 SSF53300, 2 hits
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q8BND4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPILLFLIDT SASMNQRTDL GTSYLDIAKG AVELFLKLRA RDPASRGDRY
60 70 80 90 100
MLVTYDEPPY CIKAGWKENH ATFMNELKNL QASGLTTLGQ ALRSSFDLLN
110 120 130 140 150
LNRLISGIDN YGQGRNPFFL EPSILITITD GNKLTSTASV QEELHLPLNS
160 170 180 190 200
PLPGSELTKE PFRWDQRLFA LVLRLPGVAS TEPEQLGSVP SDESAITQMC
210 220 230 240 250
EVTGGRSYCV RTQRMLNQCL ESLVQKVQSG VVINFEKTGP DPLPVGEDTL
260 270 280 290 300
MELCRPSNLF AAQPWHSCHK LIYVRPNSKT GVPVGHWPIP ESFWPEQNLP
310 320 330 340 350
SLPPRTSHPV VRFSCVDCEP MVIDKLPFDK YELEPSPLTQ YILERKSPHT
360 370 380 390 400
CWQVFVTSSS KYNELGYPFG YLKASTTLTC VNLFVMPYNY PVLLPLLDDL
410 420 430 440 450
FKVHKLKPNL KWRQAFDSYL KTLPPYYLIT KLESDQILAS VGKKPPQEIG
460 470 480 490 500
IKVKNHSACG LPLAHNKSFR KLLKEIIGES APRLTELNPK EFAGFQVGLL
510 520 530 540 550
NKDLKPQTYR NAYDIPRRGL LDQLTRMRSN LLQTRKFIVG QDEDSLHSVP
560 570 580 590 600
VAQMGNYQEY LKMLASPLRE LDPDQPKRLH TFGNPFKQDK KGMMIDEADE
610 620 630 640 650
FVVGPQNKVK RPGEPNSPMS SKRRRSMSLL LRRAQTAPTV TNHVGGKGPL
660 670 680 690 700
SASWFPSCPS LVKHTFGHPD TTVIHDTHEE KMENGQSPPD GFLLKSAPAE
710 720 730 740 750
FMNVSGESFI SSQLDSLSDD FTGLRKDGFI HKPGNNILLG GAKTCSLSVA
760 770 780 790 800
DQKITMASAL ETVPNSMQIT PAMAQGINAD IKHQLMKEVR KFGRKYERIF
810 820 830 840 850
ILLEEVQGPL ETKKQFVEFT IKEAARFKRR VLIQYLEKVL EKIDSHHLLN
860
NVNHINSRSS C
Length:861
Mass (Da):96,941
Last modified:March 1, 2003 - v1
Checksum:i22D5D4A229FE08CD
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PXU1E9PXU1_MOUSE
Integrator complex subunit 6-like
Ints6l Ddx26b
489Annotation score:
F6WNG1F6WNG1_MOUSE
Integrator complex subunit 6-like
Ints6l Ddx26b
638Annotation score:
F6RIR5F6RIR5_MOUSE
Integrator complex subunit 6-like
Ints6l Ddx26b
78Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083942 mRNA Translation: BAC39076.1
BC066792 mRNA Translation: AAH66792.1
CCDSiCCDS30145.1
RefSeqiNP_766367.1, NM_172779.4
UniGeneiMm.474772

Genome annotation databases

EnsembliENSMUST00000039374; ENSMUSP00000035379; ENSMUSG00000035967
ENSMUST00000132428; ENSMUSP00000138630; ENSMUSG00000035967
ENSMUST00000186445; ENSMUSP00000139507; ENSMUSG00000035967
GeneIDi236790
KEGGimmu:236790
UCSCiuc009tgg.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK083942 mRNA Translation: BAC39076.1
BC066792 mRNA Translation: AAH66792.1
CCDSiCCDS30145.1
RefSeqiNP_766367.1, NM_172779.4
UniGeneiMm.474772

3D structure databases

ProteinModelPortaliQ8BND4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000035379

PTM databases

iPTMnetiQ8BND4
PhosphoSitePlusiQ8BND4

Proteomic databases

EPDiQ8BND4
MaxQBiQ8BND4
PaxDbiQ8BND4
PeptideAtlasiQ8BND4
PRIDEiQ8BND4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039374; ENSMUSP00000035379; ENSMUSG00000035967
ENSMUST00000132428; ENSMUSP00000138630; ENSMUSG00000035967
ENSMUST00000186445; ENSMUSP00000139507; ENSMUSG00000035967
GeneIDi236790
KEGGimmu:236790
UCSCiuc009tgg.2 mouse

Organism-specific databases

CTDi203522
MGIiMGI:2442593 Ints6l

Phylogenomic databases

eggNOGiKOG3768 Eukaryota
ENOG410XRER LUCA
GeneTreeiENSGT00390000016655
HOGENOMiHOG000015308
HOVERGENiHBG081468
InParanoidiQ8BND4
KOiK13180
OMAiGMSLTHN
OrthoDBiEOG091G03YA
PhylomeDBiQ8BND4
TreeFamiTF323386

Miscellaneous databases

PROiPR:Q8BND4
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000035967 Expressed in 261 organ(s), highest expression level in pituitary gland
CleanExiMM_DDX26B
ExpressionAtlasiQ8BND4 baseline and differential
GenevisibleiQ8BND4 MM

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR029307 INT_SG_DDX_CT_C
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF15300 INT_SG_DDX_CT_C, 1 hit
PF13519 VWA_2, 1 hit
SUPFAMiSSF53300 SSF53300, 2 hits
PROSITEiView protein in PROSITE
PS50234 VWFA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiINT6L_MOUSE
AccessioniPrimary (citable) accession number: Q8BND4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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