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Entry version 142 (29 Sep 2021)
Sequence version 3 (27 Jul 2011)
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Protein

WD repeat-containing protein 35

Gene

Wdr35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking (PubMed:21473986).

May promote CASP3 activation and TNF-stimulated apoptosis (By similarity).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5610787, Hedgehog 'off' state
R-MMU-5620924, Intraflagellar transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat-containing protein 35Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Wdr35Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1921932, Wdr35

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000066643

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000513851 – 1181WD repeat-containing protein 35Add BLAST1181

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BND3

PeptideAtlas

More...
PeptideAtlasi
Q8BND3

PRoteomics IDEntifications database

More...
PRIDEi
Q8BND3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
297644 [Q8BND3-1]
297645 [Q8BND3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BND3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BND3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000066643, Expressed in testis and 248 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BND3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BND3, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the IFT complex A (IFT-A) complex. IFT-A complex is divided into a core subcomplex composed of IFT122:IFT140:WDR19 which is associated with TULP3 and a peripheral subcomplex composed of IFT43:WDR35:TTC21B.

Interacts directy with IFT122, ITF43 and TTC21B.

Interacts with IFT43.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
216937, 2 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-5027, IFT-A complex

Protein interaction database and analysis system

More...
IntActi
Q8BND3, 1 interactor

Molecular INTeraction database

More...
MINTi
Q8BND3

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000082895

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BND3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BND3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati12 – 51WD 1Add BLAST40
Repeati69 – 108WD 2Add BLAST40
Repeati113 – 152WD 3Add BLAST40
Repeati154 – 193WD 4Add BLAST40
Repeati502 – 539WD 5Add BLAST38

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2041, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155745

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004048_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BND3

Identification of Orthologs from Complete Genome Data

More...
OMAi
NACPLCH

Database of Orthologous Groups

More...
OrthoDBi
95796at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BND3

TreeFam database of animal gene trees

More...
TreeFami
TF314076

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024977, Apc4_WD40_dom
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf
IPR017233, WDR35

The PANTHER Classification System

More...
PANTHERi
PTHR16517:SF1, PTHR16517:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12894, ANAPC4_WD40, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037536, WD_repeat_p35, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BND3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFFYLSKKIA VPNNVKLKCI SWNKDQGFIA CGGEDGLLKV LRLETQTDDS
60 70 80 90 100
KLRGLAAPSN LSMNQNLEGH SGAVQVVTWN EQYQKLTTSD QNGLIIVWML
110 120 130 140 150
YKGSWYEEMI NNRNKSVVRS MSWNADGQKI CIVYEDGAVI VGSVDGNRIW
160 170 180 190 200
GKDLKGIQLC HVTWSADSKI LLFGMANGEI HIYDNQGNFI MKMKLNCLVN
210 220 230 240 250
VTGAISIAGI HWYHGTEGYV EPDCPCLAIC FDNGRCQIMR HENDQNPVLI
260 270 280 290 300
DTGMYVVGIQ WNHIGSVLAV AGSQKVVTQD KDINIVQFYT PFGEHLGTLK
310 320 330 340 350
VPGKQMCSLS WEGGGLKIAL AVDSFIYFAN IRPDYKWGYC SNTVVYAYTR
360 370 380 390 400
PDRPEYCVVF WDTKNSEKYV KYVKSLISIT TCGDFCILAT KADENHPQEE
410 420 430 440 450
NEMETFGATF VLVLCNSIGT PLDPKYIDLV PLFVAMTKTH VIAASKEAFY
460 470 480 490 500
TWQYRVAKKL TALEINQITR SRKEGRERIY HVDDVPSGSV DGVFDYSKAI
510 520 530 540 550
QGTRDPICAI TASDKTLIVG RESGVIQRYS FPNVALIQKY SLDCRACQLS
560 570 580 590 600
LNCNSSRLAI IDIAGVLTFF DLDTRVTDST GQQVVGELLK LERKDVWDMK
610 620 630 640 650
WAKDNPDLFA MMEKTRMYVF RNLDPEEPIQ TSGYICNFED LEIKSVLLDE
660 670 680 690 700
ILKDPEHPSK DYIMNFEIRS LRDSRALIEK VGIEDASQFI EDNPHPRLWR
710 720 730 740 750
LLAEAALQKL DLYTAQQAFV RCKDYQGIKF VKLLGNLQSE SMKQAEVIAY
760 770 780 790 800
FGRFEDAERM YQDMDRRDLA IGLRMKLGDW FRVLQLLKTG SGDADDSLLE
810 820 830 840 850
QANNAIGEYF ADRQKWQNAV QYYVKGRNQE RLAECYYMLE DYEGLETLAN
860 870 880 890 900
SLPENHKLLP EIAQMFVRVG MCEQAVSAFL KCNQPKAAVD TCVHLNQWNK
910 920 930 940 950
AVELAKSHSM KEIGSLLARY ASHLLEKNKT LDAIELYRKA SYFFDAAKLM
960 970 980 990 1000
YKIADEEAKK RTKPLRVKKL YVLSALLIEQ YHEQMKNAQR GKVKGKNSEA
1010 1020 1030 1040 1050
TSALAGLLEE EVLSTTSRFT DNAWRGAEAY HFFILAQRQL YEGYVDTALK
1060 1070 1080 1090 1100
TALHLRDYED IIPSVEIYSL LALCACASRA FGTCSKAFIK LESLETLSAE
1110 1120 1130 1140 1150
QKQQYEDLAL EIFTKHTPKD NRKSELNSLL EGGEGKLPTC IATGSPIIEY
1160 1170 1180
QFWVCKVCKH YVLAQEISNY NFCPLCHSSV E
Length:1,181
Mass (Da):133,991
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF69BA836E9CA65CE
GO
Isoform 2 (identifier: Q8BND3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     399-409: Missing.

Show »
Length:1,170
Mass (Da):132,752
Checksum:iC74FFD8594961B2E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E0CYD5E0CYD5_MOUSE
WD repeat-containing protein 35
Wdr35
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti634Y → H in AAH56925 (PubMed:15489334).Curated1
Sequence conflicti828N → D in BAC39081 (PubMed:16141072).Curated1
Sequence conflicti915S → Y in BAC26663 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_009733399 – 409Missing in isoform 2. 1 PublicationAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK029896 mRNA Translation: BAC26663.1
AK083971 mRNA Translation: BAC39081.1
AC110376 Genomic DNA No translation available.
BC056925 mRNA Translation: AAH56925.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25807.1 [Q8BND3-1]
CCDS49027.1 [Q8BND3-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001152999.1, NM_001159527.1 [Q8BND3-2]
NP_766058.3, NM_172470.3 [Q8BND3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000085745; ENSMUSP00000082895; ENSMUSG00000066643 [Q8BND3-1]
ENSMUST00000111113; ENSMUSP00000106742; ENSMUSG00000066643 [Q8BND3-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
74682

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:74682

UCSC genome browser

More...
UCSCi
uc007naj.2, mouse [Q8BND3-1]
uc007nak.2, mouse [Q8BND3-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029896 mRNA Translation: BAC26663.1
AK083971 mRNA Translation: BAC39081.1
AC110376 Genomic DNA No translation available.
BC056925 mRNA Translation: AAH56925.1
CCDSiCCDS25807.1 [Q8BND3-1]
CCDS49027.1 [Q8BND3-2]
RefSeqiNP_001152999.1, NM_001159527.1 [Q8BND3-2]
NP_766058.3, NM_172470.3 [Q8BND3-1]

3D structure databases

SMRiQ8BND3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi216937, 2 interactors
ComplexPortaliCPX-5027, IFT-A complex
IntActiQ8BND3, 1 interactor
MINTiQ8BND3
STRINGi10090.ENSMUSP00000082895

PTM databases

iPTMnetiQ8BND3
PhosphoSitePlusiQ8BND3

Proteomic databases

PaxDbiQ8BND3
PeptideAtlasiQ8BND3
PRIDEiQ8BND3
ProteomicsDBi297644 [Q8BND3-1]
297645 [Q8BND3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
50378, 65 antibodies

The DNASU plasmid repository

More...
DNASUi
74682

Genome annotation databases

EnsembliENSMUST00000085745; ENSMUSP00000082895; ENSMUSG00000066643 [Q8BND3-1]
ENSMUST00000111113; ENSMUSP00000106742; ENSMUSG00000066643 [Q8BND3-2]
GeneIDi74682
KEGGimmu:74682
UCSCiuc007naj.2, mouse [Q8BND3-1]
uc007nak.2, mouse [Q8BND3-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57539
MGIiMGI:1921932, Wdr35
VEuPathDBiHostDB:ENSMUSG00000066643

Phylogenomic databases

eggNOGiKOG2041, Eukaryota
GeneTreeiENSGT00940000155745
HOGENOMiCLU_004048_1_0_1
InParanoidiQ8BND3
OMAiNACPLCH
OrthoDBi95796at2759
PhylomeDBiQ8BND3
TreeFamiTF314076

Enzyme and pathway databases

ReactomeiR-MMU-5610787, Hedgehog 'off' state
R-MMU-5620924, Intraflagellar transport

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
74682, 2 hits in 61 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Wdr35, mouse

Protein Ontology

More...
PROi
PR:Q8BND3
RNActiQ8BND3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000066643, Expressed in testis and 248 other tissues
ExpressionAtlasiQ8BND3, baseline and differential
GenevisibleiQ8BND3, MM

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR024977, Apc4_WD40_dom
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR036322, WD40_repeat_dom_sf
IPR017233, WDR35
PANTHERiPTHR16517:SF1, PTHR16517:SF1, 1 hit
PfamiView protein in Pfam
PF12894, ANAPC4_WD40, 1 hit
PIRSFiPIRSF037536, WD_repeat_p35, 1 hit
SMARTiView protein in SMART
SM00320, WD40, 4 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDR35_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BND3
Secondary accession number(s): E9QLW3, Q8CDL4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: July 27, 2011
Last modified: September 29, 2021
This is version 142 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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