We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q8BN57 (CC033_MOUSE)
Protein
Protein C3orf33 homolog
Gene
N/A
Organism
Mus musculus (Mouse)
Status
Functioni
May play a role in transcription regulation.
By similarityGO - Biological processi
- negative regulation of ERK1 and ERK2 cascade Source: UniProtKB
- regulation of DNA-binding transcription factor activity Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: Protein C3orf33 homolog |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:3607716, E130311K13Rik |
VEuPathDBi | HostDB:ENSMUSG00000048581 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass membrane protein Curated
Extracellular region or secreted
- extracellular space Source: UniProtKB
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 36 – 53 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedBy similarity | |||
ChainiPRO_0000254578 | 2 – 294 | Protein C3orf33 homologAdd BLAST | 293 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylalanineBy similarity | 1 |
Keywords - PTMi
AcetylationProteomic databases
EPDi | Q8BN57 |
MaxQBi | Q8BN57 |
PaxDbi | Q8BN57 |
PeptideAtlasi | Q8BN57 |
PRIDEi | Q8BN57 |
PTM databases
iPTMneti | Q8BN57 |
PhosphoSitePlusi | Q8BN57 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000048581, Expressed in interventricular septum and 256 other tissues |
Genevisiblei | Q8BN57, MM |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 244 – 271 | DisorderedSequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 254 – 268 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QR9T, Eukaryota |
GeneTreei | ENSGT00390000004493 |
HOGENOMi | CLU_069834_0_0_1 |
InParanoidi | Q8BN57 |
OMAi | YWRIHRN |
OrthoDBi | 1030642at2759 |
PhylomeDBi | Q8BN57 |
TreeFami | TF313180 |
Family and domain databases
Gene3Di | 2.40.50.90, 1 hit |
InterProi | View protein in InterPro IPR042421, C3orf33-like IPR035437, SNase_OB-fold_sf |
PANTHERi | PTHR28434, PTHR28434, 1 hit |
SUPFAMi | SSF50199, SSF50199, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8BN57-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARPPASLGS QAPDRDRGEA NVVTRVSQWA DNHLRLVQNI STGMAIAGIM
60 70 80 90 100
LLIRSVRLTS KFTTSSDIPV EFIRKKVKLR GRLQRITECG LEIEHIPITL
110 120 130 140 150
PFISSWKEEP RGVLLVKLAG VELTESGKVW LQAELKPSQL LWFQLLGKED
160 170 180 190 200
SALFCYLLVN KGGYFNVNLN EEILRRGLGK TVLVKGLNYD SKTHWKIHRN
210 220 230 240 250
LLKAELTALK KGEGIWKEES EKESYFRKLK DSWRERWTKD NDLKPAGADL
260 270 280 290
GSTKDSYHDS RRRASGKGKD SVSNYSFFLK LREFVSRLHF WRKG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK087526 mRNA Translation: BAC39912.1 BC125500 mRNA Translation: AAI25501.1 BC132160 mRNA Translation: AAI32161.1 |
CCDSi | CCDS38445.1 |
RefSeqi | NP_808524.1, NM_177856.4 |
Genome annotation databases
Ensembli | ENSMUST00000061706; ENSMUSP00000058114; ENSMUSG00000048581 |
GeneIDi | 329659 |
KEGGi | mmu:329659 |
UCSCi | uc008pkb.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK087526 mRNA Translation: BAC39912.1 BC125500 mRNA Translation: AAI25501.1 BC132160 mRNA Translation: AAI32161.1 |
CCDSi | CCDS38445.1 |
RefSeqi | NP_808524.1, NM_177856.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
PTM databases
iPTMneti | Q8BN57 |
PhosphoSitePlusi | Q8BN57 |
Proteomic databases
EPDi | Q8BN57 |
MaxQBi | Q8BN57 |
PaxDbi | Q8BN57 |
PeptideAtlasi | Q8BN57 |
PRIDEi | Q8BN57 |
Protocols and materials databases
Antibodypediai | 46752, 53 antibodies from 12 providers |
Genome annotation databases
Ensembli | ENSMUST00000061706; ENSMUSP00000058114; ENSMUSG00000048581 |
GeneIDi | 329659 |
KEGGi | mmu:329659 |
UCSCi | uc008pkb.1, mouse |
Organism-specific databases
MGIi | MGI:3607716, E130311K13Rik |
VEuPathDBi | HostDB:ENSMUSG00000048581 |
Phylogenomic databases
eggNOGi | ENOG502QR9T, Eukaryota |
GeneTreei | ENSGT00390000004493 |
HOGENOMi | CLU_069834_0_0_1 |
InParanoidi | Q8BN57 |
OMAi | YWRIHRN |
OrthoDBi | 1030642at2759 |
PhylomeDBi | Q8BN57 |
TreeFami | TF313180 |
Miscellaneous databases
BioGRID-ORCSi | 329659, 1 hit in 64 CRISPR screens |
PROi | PR:Q8BN57 |
RNActi | Q8BN57, protein |
Gene expression databases
Bgeei | ENSMUSG00000048581, Expressed in interventricular septum and 256 other tissues |
Genevisiblei | Q8BN57, MM |
Family and domain databases
Gene3Di | 2.40.50.90, 1 hit |
InterProi | View protein in InterPro IPR042421, C3orf33-like IPR035437, SNase_OB-fold_sf |
PANTHERi | PTHR28434, PTHR28434, 1 hit |
SUPFAMi | SSF50199, SSF50199, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CC033_MOUSE | |
Accessioni | Q8BN57Primary (citable) accession number: Q8BN57 Secondary accession number(s): Q059W9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | March 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot