Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 125 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

F-box only protein 38

Gene

Fbxo38

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of PDCD1/PD-1, thereby regulating T-cells-mediated immunity (PubMed:30487606). Required for anti-tumor activity of T-cells by promoting the degradation of PDCD1/PD-1; the PDCD1-mediated inhibitory pathway being exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:30487606). May indirectly stimulate the activity of transcription factor KLF7, a regulator of neuronal differentiation, without promoting KLF7 ubiquitination (PubMed:14729953, PubMed:16990251).3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.By similarity
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAdaptive immunity, Immunity, Ubl conjugation pathway

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
F-box only protein 38Curated
Alternative name(s):
Modulator of KLF7 activity1 Publication
Short name:
MoKA1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fbxo38Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444639, Fbxo38

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Conditional deletion in T-cells does not affect the development, peripheral homeostasis and population of memory T-cells, but leads to faster tumor progression (PubMed:30487606). Faster tumor progression is caused by higher levels of Pdcd1/PD-1 in tumor-infiltrating T-cells (PubMed:30487606).1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi194 – 196LHL → AHA: Decreased cytoplasmic localization. 1 Publication3
Mutagenesisi264 – 275LEHLE…RVPFL → AEHAEMVRVPFA: Decreased cytoplasmic localization. 1 PublicationAdd BLAST12
Mutagenesisi902 – 904KRK → RRR: Impaired nuclear localization. 1 Publication3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001199341 – 1194F-box only protein 38Add BLAST1194

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei592PhosphothreonineCombined sources1
Modified residuei599PhosphoserineCombined sources1
Modified residuei601PhosphoserineCombined sources1
Modified residuei607PhosphoserineCombined sources1
Modified residuei742PhosphoserineBy similarity1
Modified residuei746PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BMI0

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BMI0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8BMI0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BMI0

PeptideAtlas

More...
PeptideAtlasi
Q8BMI0

PRoteomics IDEntifications database

More...
PRIDEi
Q8BMI0

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2309, 1 N-Linked glycan (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q8BMI0, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BMI0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BMI0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed at high levels in embryo (developing brain, spinal chord, branchial arms and limbs) (PubMed:14729953). Widely expressed at low levels in adult tissues, with highest expression in testis. Expressed in postmeiotic spermatids (PubMed:14729953).1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In embryo expressed at 11 dpc, 15 dpc and 17 dpc.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by IL2 (PubMed:30487606). Down-regulated in tumor-infiltrating T-cells (PubMed:30487606).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000042211, Expressed in saccule of membranous labyrinth and 300 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BMI0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BMI0, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO38) composed of CUL1, SKP1, RBX1 and FBXO38 (By similarity).

Interacts with KLF7 (PubMed:14729953).

Interacts with PDCD1/PD-1 (By similarity).

By similarity1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000047541

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BMI0, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 75F-boxPROSITE-ProRule annotationAdd BLAST46

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni59 – 119Interaction with KLF71 PublicationAdd BLAST61

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi194 – 201Nuclear export signal 11 Publication8
Motifi307 – 316Nuclear export signal 21 Publication10
Motifi451 – 460Nuclear export signal 31 Publication10
Motifi902 – 905Nuclear localization signal1 Publication4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi705 – 712Poly-Ser8

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSUC, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013163

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010774_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BMI0

KEGG Orthology (KO)

More...
KOi
K10313

Identification of Orthologs from Complete Genome Data

More...
OMAi
CKEEYPR

Database of Orthologous Groups

More...
OrthoDBi
63661at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BMI0

TreeFam database of animal gene trees

More...
TreeFami
TF331125

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036047, F-box-like_dom_sf
IPR001810, F-box_dom
IPR042354, FBX38
IPR032675, LRR_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14753, PTHR14753, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00646, F-box, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81383, SSF81383, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8BMI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPRKKSAKV CVMDSEVAEE MTADEEKDYM NQLSHEVLCH IFRYLPLQDI
60 70 80 90 100
MCMECLSRKL KEAVTLYLRV VRVVDLCAGR WWEYMPSGFT DSSFLTLLKK
110 120 130 140 150
MPDVEQLYGL HPRYLERRRV RGQEAFSIPG VLEALQACPN LVGVETSHLE
160 170 180 190 200
LVESIWTYMP HVHILGKFRN RNGAFPIPPE NKLKIPIGAK IQTLHLVGVN
210 220 230 240 250
VPEIPCIPML RHLYMKWVRL TKPQPFKDFL CISLRTFVMR NCAGPTNSLK
260 270 280 290 300
YVPLVTGLAS ARNLEHLEMV RVPFLGGLIQ HVVEDSWRSG GFRNLHTIVL
310 320 330 340 350
GACKNALEVD LGYLIITAAR RLHEVRIQPS LTKDGVFSAL KMAELEFPQF
360 370 380 390 400
ETLHLGYVDE FLLQSRMANA DLVKYGLADV VENPGIITDI GMKAVNEVFS
410 420 430 440 450
CIKYLAIYNC PHLHNPYNWI SDHSRWMRLV DINLVRCHAL KLDSFGQFVE
460 470 480 490 500
LLPSLEFISL DQMFREPPKG CARVGLSAGT GIGVSSALVS NQNSNNDNDN
510 520 530 540 550
NAPNNNANLH DNNHHHPDDS DDDNDFRPDL QAGEAQFAAD ALNEMEDMVQ
560 570 580 590 600
EDGELVAESG NGMPAHNREV LPVDADEEQA GPSGLQRVVK PTPIADHDSE
610 620 630 640 650
SDDEEDSLEL QEVWAPKNGT RRYSEREEKT GDSGQSRETA VSGKGKTPLR
660 670 680 690 700
KRCNNSHQTG QAKPFPLEES SCEKGCQVTS EQIKADMKAA RDVSEKKKSK
710 720 730 740 750
DVYPSCSSSS SSTAASTAGN ASSPSTASQS PDFARTVTSS GSSEPSPPEV
760 770 780 790 800
DVSRQCVCSP GGSEDSEAME EGDAESSVCP RCCCLRPQES QRRTGRCSDE
810 820 830 840 850
ERPSTSRACV VNGADGTRSA FSFRTLPQGG SSGPAHDERT NGSGCGATGE
860 870 880 890 900
DRRGSSQPES CDVQSNEDYP RRPLTRARSR LSHVPLISES EVAKTKPCHA
910 920 930 940 950
MKRKRTADKS TSTSDPVIED DHVQVLVLKS KNLVGVTMTN CGITDLVLKD
960 970 980 990 1000
CPKMMFIHAT RCRVLKHLKV ENAPIVNRFD YAQCKKLNMD QVLDQILRMP
1010 1020 1030 1040 1050
PERNRIIYLR PMQQVDTLTL EQKLFSGPYP YHICIIHEFS NPPNVRNKVR
1060 1070 1080 1090 1100
IRNWMDTIAN INQELIKYEF FLEATRTEED LKKYPKYPWG REIYTLEGVV
1110 1120 1130 1140 1150
DGAPYSMISD FPWLRSLRTA EPNSFARYDF EDDEESTIYA PRRKGQLSAD
1160 1170 1180 1190
ICMETIGEEI SEMRQMKRGI FQRVVAIFIH YCDVNGEPVE DDYI
Length:1,194
Mass (Da):133,928
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40F973C9638824A8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A494BB05A0A494BB05_MOUSE
F-box only protein 38
Fbxo38
179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti659T → M in BAC40718 (PubMed:16141072).Curated1
Sequence conflicti712Missing in AAP31028 (PubMed:14729953).Curated1
Sequence conflicti712Missing in BAC40718 (PubMed:16141072).Curated1
Sequence conflicti715A → T in BAC40718 (PubMed:16141072).Curated1
Sequence conflicti1163M → K in BAC27358 (PubMed:16141072).Curated1
Sequence conflicti1185N → H in BAC27358 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY267463 mRNA Translation: AAP31028.1
AK089046 mRNA Translation: BAC40718.1
AK031096 mRNA Translation: BAC27250.1
AK031347 mRNA Translation: BAC27358.1
BC056348 mRNA Translation: AAH56348.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37841.1

NCBI Reference Sequences

More...
RefSeqi
NP_598897.2, NM_134136.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000048688; ENSMUSP00000047541; ENSMUSG00000042211

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
107035

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:107035

UCSC genome browser

More...
UCSCi
uc012bdv.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY267463 mRNA Translation: AAP31028.1
AK089046 mRNA Translation: BAC40718.1
AK031096 mRNA Translation: BAC27250.1
AK031347 mRNA Translation: BAC27358.1
BC056348 mRNA Translation: AAH56348.1
CCDSiCCDS37841.1
RefSeqiNP_598897.2, NM_134136.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000047541

PTM databases

GlyConnecti2309, 1 N-Linked glycan (1 site)
GlyGeniQ8BMI0, 1 site
iPTMnetiQ8BMI0
PhosphoSitePlusiQ8BMI0

Proteomic databases

EPDiQ8BMI0
jPOSTiQ8BMI0
MaxQBiQ8BMI0
PaxDbiQ8BMI0
PeptideAtlasiQ8BMI0
PRIDEiQ8BMI0

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27733, 65 antibodies

Genome annotation databases

EnsembliENSMUST00000048688; ENSMUSP00000047541; ENSMUSG00000042211
GeneIDi107035
KEGGimmu:107035
UCSCiuc012bdv.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81545
MGIiMGI:2444639, Fbxo38

Phylogenomic databases

eggNOGiENOG502QSUC, Eukaryota
GeneTreeiENSGT00390000013163
HOGENOMiCLU_010774_0_0_1
InParanoidiQ8BMI0
KOiK10313
OMAiCKEEYPR
OrthoDBi63661at2759
PhylomeDBiQ8BMI0
TreeFamiTF331125

Enzyme and pathway databases

UniPathwayiUPA00143

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
107035, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Fbxo38, mouse

Protein Ontology

More...
PROi
PR:Q8BMI0
RNActiQ8BMI0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000042211, Expressed in saccule of membranous labyrinth and 300 other tissues
ExpressionAtlasiQ8BMI0, baseline and differential
GenevisibleiQ8BMI0, MM

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR036047, F-box-like_dom_sf
IPR001810, F-box_dom
IPR042354, FBX38
IPR032675, LRR_dom_sf
PANTHERiPTHR14753, PTHR14753, 1 hit
PfamiView protein in Pfam
PF00646, F-box, 1 hit
SUPFAMiSSF81383, SSF81383, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFBX38_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BMI0
Secondary accession number(s): Q8BTQ4, Q8C0H4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 125 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again