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Protein

Cytochrome P450 20A1

Gene

Cyp20a1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi409Iron (heme axial ligand)By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450 20A1 (EC:1.14.-.-)
Gene namesi
Name:Cyp20a1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1925201 Cyp20a1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003180961 – 462Cytochrome P450 20A1Add BLAST462

Proteomic databases

EPDiQ8BKE6
MaxQBiQ8BKE6
PaxDbiQ8BKE6
PeptideAtlasiQ8BKE6
PRIDEiQ8BKE6

PTM databases

iPTMnetiQ8BKE6
PhosphoSitePlusiQ8BKE6

Expressioni

Gene expression databases

BgeeiENSMUSG00000049439 Expressed in 240 organ(s), highest expression level in indifferent gonad
ExpressionAtlasiQ8BKE6 baseline and differential
GenevisibleiQ8BKE6 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050823

Structurei

3D structure databases

ProteinModelPortaliQ8BKE6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00500000044939
HOGENOMiHOG000111913
HOVERGENiHBG076231
InParanoidiQ8BKE6
KOiK07435
OMAiCTWAVYF
OrthoDBiEOG091G0JCG
PhylomeDBiQ8BKE6
TreeFamiTF105089

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
SUPFAMiSSF48264 SSF48264, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8BKE6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDFAIFAVT FLLALVGAVL YLYPASRQAS GIPGLTPTEE KDGNLPDIVN
60 70 80 90 100
SGSLHEFLVN LHERYGPVVS FWFGRRLVVS LGTTDVLKQH FNPNKTSDPF
110 120 130 140 150
ETMLKSLLGY QSGGGSAGED HVRRKLYGDA VTASLHSNFP LLLQLSEELL
160 170 180 190 200
DKWLSYPETQ HIPLSQHMLG FALKFVTRMV LGSTFEDEQE VIRFQKIHGT
210 220 230 240 250
VWSEIGKGFL DGSLDKNTTR KKQYQEALMQ LESTLKKIIK ERKGGNFRQH
260 270 280 290 300
TFIDSLTQGK LNEQQILEDC VVFSLASCII TARLCTWTIH FLTTTGEVQK
310 320 330 340 350
KLCKEIDQVL GEGPITSEKI EQLSYCQQVL FETVRTAKLT PVSARLQDIE
360 370 380 390 400
GKVGPFVIPK ETLVLYALGV VLQDPSTWPL PHRFDPDRFA DEPVMKVFSS
410 420 430 440 450
LGFSGTWECP ELRFAYMVTA VLVSVLLKRL RLLAVDRQVF EMKYELVTSA
460
REEAWITVSK RH
Length:462
Mass (Da):52,149
Last modified:March 1, 2003 - v1
Checksum:i4ADF835E04E291F3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3QPT8J3QPT8_MOUSE
Cytochrome P450 20A1
Cyp20a1
44Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053388 mRNA Translation: BAC35373.1
CCDSiCCDS14990.1
RefSeqiNP_084289.1, NM_030013.3
UniGeneiMm.197640

Genome annotation databases

EnsembliENSMUST00000060608; ENSMUSP00000050823; ENSMUSG00000049439
GeneIDi77951
KEGGimmu:77951
UCSCiuc007bem.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053388 mRNA Translation: BAC35373.1
CCDSiCCDS14990.1
RefSeqiNP_084289.1, NM_030013.3
UniGeneiMm.197640

3D structure databases

ProteinModelPortaliQ8BKE6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000050823

PTM databases

iPTMnetiQ8BKE6
PhosphoSitePlusiQ8BKE6

Proteomic databases

EPDiQ8BKE6
MaxQBiQ8BKE6
PaxDbiQ8BKE6
PeptideAtlasiQ8BKE6
PRIDEiQ8BKE6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000060608; ENSMUSP00000050823; ENSMUSG00000049439
GeneIDi77951
KEGGimmu:77951
UCSCiuc007bem.1 mouse

Organism-specific databases

CTDi57404
MGIiMGI:1925201 Cyp20a1

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00500000044939
HOGENOMiHOG000111913
HOVERGENiHBG076231
InParanoidiQ8BKE6
KOiK07435
OMAiCTWAVYF
OrthoDBiEOG091G0JCG
PhylomeDBiQ8BKE6
TreeFamiTF105089

Miscellaneous databases

PROiPR:Q8BKE6
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000049439 Expressed in 240 organ(s), highest expression level in indifferent gonad
ExpressionAtlasiQ8BKE6 baseline and differential
GenevisibleiQ8BKE6 MM

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
SUPFAMiSSF48264 SSF48264, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCP20A_MOUSE
AccessioniPrimary (citable) accession number: Q8BKE6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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