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Protein

HSPB1-associated protein 1

Gene

Hspbap1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in cellular stress response.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
HSPB1-associated protein 1
Alternative name(s):
27 kDa heat shock protein-associated protein 1
Protein associated with small stress protein 1
Gene namesi
Name:Hspbap1
Synonyms:Pass1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1913917 Hspbap1

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002841141 – 483HSPB1-associated protein 1Add BLAST483

Proteomic databases

EPDiQ8BK58
MaxQBiQ8BK58
PaxDbiQ8BK58
PeptideAtlasiQ8BK58
PRIDEiQ8BK58

PTM databases

PhosphoSitePlusiQ8BK58

Expressioni

Gene expression databases

BgeeiENSMUSG00000022849 Expressed in 133 organ(s), highest expression level in embryo
CleanExiMM_HSPBAP1
GenevisibleiQ8BK58 MM

Interactioni

Subunit structurei

Interacts with CRYAB and HSPB1.1 Publication

Protein-protein interaction databases

BioGridi211634, 1 interactor
STRINGi10090.ENSMUSP00000023555

Structurei

3D structure databases

ProteinModelPortaliQ8BK58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini124 – 288JmjCPROSITE-ProRule annotationAdd BLAST165

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni88 – 208Interaction with HSPB1By similarityAdd BLAST121

Phylogenomic databases

eggNOGiKOG2132 Eukaryota
ENOG410XQDR LUCA
GeneTreeiENSGT00530000062914
HOGENOMiHOG000068192
HOVERGENiHBG099816
InParanoidiQ8BK58
KOiK19375
OMAiNTRAWLN
OrthoDBiEOG091G0DDY
TreeFamiTF315056

Family and domain databases

InterProiView protein in InterPro
IPR013296 HSPB1-associated_protein_1
IPR003347 JmjC_dom
PRINTSiPR01886 PASS1
SMARTiView protein in SMART
SM00558 JmjC, 1 hit
PROSITEiView protein in PROSITE
PS51184 JMJC, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BK58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAGCEGIAP PTLGERTVGE EGEPVKPFTP EKAKEIIMSL QQPAIFCNMV
60 70 80 90 100
FDWPSRHWTA KHLSKVLEGK QIRFRMGLRG TGTVPQYETE CSYVDATLEE
110 120 130 140 150
FLTWNCDQSS ISGPFKDYEH SKFWAYADYK YFVTLFEDKT DVFQEVVWSD
160 170 180 190 200
FGFPGRNGQE STLWIGSFGA HTPCHLDSYG CNLVFQVQGR KRWHLFPPED
210 220 230 240 250
TPFLYPTRIP YEESSVFSKI NVVNPDLKCF PQFQKARRHM VTLSPGQVLF
260 270 280 290 300
VPRHWWHYVE SLDPVTVSIN SWIELEEDHL ARVEEAITRM LVCTLKTAED
310 320 330 340 350
PHHPRTWLNP TEVEETSHEV NSCYLNSAVC AFFDHCEKAK AVELQVLSAN
360 370 380 390 400
GAEPRVQEEH MEVEQAQGPS LTSRAEKQEA VSLFGPDLIP VTPASEERGG
410 420 430 440 450
ALEGDSEESV SSNGGHFAEL PCARRQQTSK GASALTEPLA PRGPMAHSRV
460 470 480
FVSTDDLLDC LVNPQVTRMV AQLLIQGKSC DTF
Length:483
Mass (Da):54,395
Last modified:July 27, 2011 - v2
Checksum:i520906E6F7F73EBB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti268S → G in BAC36242 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK076189 mRNA Translation: BAC36242.1
AC129574 Genomic DNA No translation available.
CCDSiCCDS28142.1
RefSeqiNP_780320.2, NM_175111.3
UniGeneiMm.45272

Genome annotation databases

EnsembliENSMUST00000023555; ENSMUSP00000023555; ENSMUSG00000022849
GeneIDi66667
KEGGimmu:66667
UCSCiuc007zbq.1 mouse

Similar proteinsi

Entry informationi

Entry nameiHBAP1_MOUSE
AccessioniPrimary (citable) accession number: Q8BK58
Secondary accession number(s): E9QML8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 99 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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