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UniProtKB - Q8BIS8 (CC126_MOUSE)
Protein
Coiled-coil domain-containing protein 126
Gene
Ccdc126
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Coiled-coil domain-containing protein 126 |
Gene namesi | Name:Ccdc126 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1889376, Ccdc126 |
VEuPathDBi | HostDB:ENSMUSG00000050786 |
Subcellular locationi
Extracellular region or secreted
- Secreted Curated
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 35 | Sequence analysisAdd BLAST | 35 | |
ChainiPRO_0000288817 | 36 – 140 | Coiled-coil domain-containing protein 126Add BLAST | 105 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 110 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
EPDi | Q8BIS8 |
MaxQBi | Q8BIS8 |
PaxDbi | Q8BIS8 |
PeptideAtlasi | Q8BIS8 |
PRIDEi | Q8BIS8 |
ProteomicsDBi | 279940 [Q8BIS8-1] 279941 [Q8BIS8-2] |
PTM databases
GlyGeni | Q8BIS8, 1 site |
iPTMneti | Q8BIS8 |
PhosphoSitePlusi | Q8BIS8 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000050786, Expressed in retina and 250 other tissues |
Genevisiblei | Q8BIS8, MM |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000058077 |
Miscellaneous databases
RNActi | Q8BIS8, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 118 – 140 | DisorderedSequence analysisAdd BLAST | 23 |
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | ENOG502RY1D, Eukaryota |
GeneTreei | ENSGT00940000153470 |
HOGENOMi | CLU_136286_0_0_1 |
InParanoidi | Q8BIS8 |
OMAi | VNASAHN |
OrthoDBi | 1333473at2759 |
PhylomeDBi | Q8BIS8 |
TreeFami | TF332515 |
Family and domain databases
InterProi | View protein in InterPro IPR042759, CCDC126 IPR027833, DUF4525 |
PANTHERi | PTHR46941, PTHR46941, 1 hit |
Pfami | View protein in Pfam PF15027, DUF4525, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q8BIS8-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFRTISRKNM SQKLSFLLLV FGLIWGLMLL HYTLQQPRRQ SSVKLREQIL
60 70 80 90 100
DLSKRYVKAL AEESRSTADV DSGASMAGYA DLKRTIAVLL DDILQRLVKL
110 120 130 140
ESKVDYIVVN GSATNTTNGT NGNLVPVTTN KRTSVSGSVR
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_025785 | 80 – 140 | ADLKR…SGSVR → VLHLPGPASLYLLSNSASQE MTHC in isoform 2. 1 PublicationAdd BLAST | 61 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK018135 mRNA Translation: BAC25544.1 AK159264 mRNA Translation: BAE34944.1 BC095987 mRNA Translation: AAH95987.1 BC117837 mRNA Translation: AAI17838.1 |
CCDSi | CCDS20125.1 [Q8BIS8-1] CCDS80531.1 [Q8BIS8-2] |
RefSeqi | NP_001298041.1, NM_001311112.1 [Q8BIS8-2] NP_780307.1, NM_175098.6 [Q8BIS8-1] XP_011239722.1, XM_011241420.2 [Q8BIS8-1] |
Genome annotation databases
Ensembli | ENSMUST00000055559; ENSMUSP00000058077; ENSMUSG00000050786 [Q8BIS8-1] ENSMUST00000114491; ENSMUSP00000110135; ENSMUSG00000050786 [Q8BIS8-2] |
GeneIDi | 57895 |
KEGGi | mmu:57895 |
UCSCi | uc009bwp.1, mouse [Q8BIS8-1] uc009bwq.1, mouse [Q8BIS8-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK018135 mRNA Translation: BAC25544.1 AK159264 mRNA Translation: BAE34944.1 BC095987 mRNA Translation: AAH95987.1 BC117837 mRNA Translation: AAI17838.1 |
CCDSi | CCDS20125.1 [Q8BIS8-1] CCDS80531.1 [Q8BIS8-2] |
RefSeqi | NP_001298041.1, NM_001311112.1 [Q8BIS8-2] NP_780307.1, NM_175098.6 [Q8BIS8-1] XP_011239722.1, XM_011241420.2 [Q8BIS8-1] |
3D structure databases
AlphaFoldDBi | Q8BIS8 |
SMRi | Q8BIS8 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000058077 |
PTM databases
GlyGeni | Q8BIS8, 1 site |
iPTMneti | Q8BIS8 |
PhosphoSitePlusi | Q8BIS8 |
Proteomic databases
EPDi | Q8BIS8 |
MaxQBi | Q8BIS8 |
PaxDbi | Q8BIS8 |
PeptideAtlasi | Q8BIS8 |
PRIDEi | Q8BIS8 |
ProteomicsDBi | 279940 [Q8BIS8-1] 279941 [Q8BIS8-2] |
Protocols and materials databases
Antibodypediai | 12117, 76 antibodies from 15 providers |
DNASUi | 57895 |
Genome annotation databases
Ensembli | ENSMUST00000055559; ENSMUSP00000058077; ENSMUSG00000050786 [Q8BIS8-1] ENSMUST00000114491; ENSMUSP00000110135; ENSMUSG00000050786 [Q8BIS8-2] |
GeneIDi | 57895 |
KEGGi | mmu:57895 |
UCSCi | uc009bwp.1, mouse [Q8BIS8-1] uc009bwq.1, mouse [Q8BIS8-2] |
Organism-specific databases
CTDi | 90693 |
MGIi | MGI:1889376, Ccdc126 |
VEuPathDBi | HostDB:ENSMUSG00000050786 |
Phylogenomic databases
eggNOGi | ENOG502RY1D, Eukaryota |
GeneTreei | ENSGT00940000153470 |
HOGENOMi | CLU_136286_0_0_1 |
InParanoidi | Q8BIS8 |
OMAi | VNASAHN |
OrthoDBi | 1333473at2759 |
PhylomeDBi | Q8BIS8 |
TreeFami | TF332515 |
Miscellaneous databases
BioGRID-ORCSi | 57895, 2 hits in 72 CRISPR screens |
ChiTaRSi | Ccdc126, mouse |
PROi | PR:Q8BIS8 |
RNActi | Q8BIS8, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000050786, Expressed in retina and 250 other tissues |
Genevisiblei | Q8BIS8, MM |
Family and domain databases
InterProi | View protein in InterPro IPR042759, CCDC126 IPR027833, DUF4525 |
PANTHERi | PTHR46941, PTHR46941, 1 hit |
Pfami | View protein in Pfam PF15027, DUF4525, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CC126_MOUSE | |
Accessioni | Q8BIS8Primary (citable) accession number: Q8BIS8 Secondary accession number(s): Q3TXH2, Q501L9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 29, 2007 |
Last sequence update: | March 1, 2003 | |
Last modified: | May 25, 2022 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot