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Entry version 145 (02 Jun 2021)
Sequence version 2 (19 Jul 2005)
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Protein

Cleavage stimulation factor subunit 2

Gene

Cstf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central
  • RNA binding Source: MGI

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processmRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-72163, mRNA Splicing - Major Pathway
R-MMU-72187, mRNA 3'-end processing
R-MMU-73856, RNA Polymerase II Transcription Termination
R-MMU-77595, Processing of Intronless Pre-mRNAs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cleavage stimulation factor subunit 2
Alternative name(s):
CF-1 64 kDa subunit
Cleavage stimulation factor 64 kDa subunit
Short name:
CSTF 64 kDa subunit
Short name:
CstF-64
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cstf2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1343054, Cstf2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000815321 – 580Cleavage stimulation factor subunit 2Add BLAST580

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei14PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki189Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei308Omega-N-methylarginineBy similarity1
Modified residuei471Omega-N-methylarginineBy similarity1
Modified residuei478Omega-N-methylarginineBy similarity1
Modified residuei521PhosphoserineBy similarity1
Modified residuei527PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BIQ5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BIQ5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BIQ5

PeptideAtlas

More...
PeptideAtlasi
Q8BIQ5

PRoteomics IDEntifications database

More...
PRIDEi
Q8BIQ5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
285381 [Q8BIQ5-1]
285382 [Q8BIQ5-2]

2D gel databases

REPRODUCTION-2DPAGE

More...
REPRODUCTION-2DPAGEi
IPI00607981

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BIQ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BIQ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in most somatic cell types (at protein level). Highly expressed in testis, except in meiotic spermatocytes.2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated during the G to S phase transition.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000031256, Expressed in ventromedial nucleus of hypothalamus and 311 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BIQ5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BIQ5, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF2 directly interacts with CSTF3, SYMPK and RPO2TC1.

Interacts with HSF1 in heat-stressed cells (By similarity).

Interacts with CPSF2, CPSF3 and FIP1L1.

Interacts with DDX1 (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
223801, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q8BIQ5, 2 interactors

Molecular INTeraction database

More...
MINTi
Q8BIQ5

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000033609

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BIQ5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
Q8BIQ5

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BIQ5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini16 – 94RRMPROSITE-ProRule annotationAdd BLAST79
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati413 – 4171; approximate5
Repeati418 – 42225
Repeati423 – 42735
Repeati428 – 4324; approximate5
Repeati433 – 4375; approximate5
Repeati438 – 44265
Repeati443 – 44775
Repeati448 – 45285
Repeati453 – 45795
Repeati458 – 462105
Repeati463 – 467115
Repeati468 – 47212; approximate5

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni108 – 248Interactions with CSTF3 and SYMPKBy similarityAdd BLAST141
Regioni311 – 331DisorderedSequence analysisAdd BLAST21
Regioni347 – 414DisorderedSequence analysisAdd BLAST68
Regioni413 – 47212 X 5 AA tandem repeats of M-E-A-R-[AG]Add BLAST60
Regioni511 – 536DisorderedSequence analysisAdd BLAST26
Regioni517 – 580Interaction with RPO2TC1By similarityAdd BLAST64

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi514 – 536Polar residuesSequence analysisAdd BLAST23

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0108, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158987

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BIQ5

Identification of Orthologs from Complete Genome Data

More...
OMAi
ASHYNSQ

Database of Orthologous Groups

More...
OrthoDBi
1455080at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BIQ5

TreeFam database of animal gene trees

More...
TreeFami
TF314948

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.20.70, 1 hit
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033105, CSTF2
IPR038192, CSTF2_C_sf
IPR025742, CSTF2_hinge
IPR026896, CSTF_C
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom

The PANTHER Classification System

More...
PANTHERi
PTHR45735:SF6, PTHR45735:SF6, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14327, CSTF2_hinge, 1 hit
PF14304, CSTF_C, 1 hit
PF00076, RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102, RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BIQ5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAGLPVRDPA VDRSLRSVFV GNIPYEATEE QLKDIFSEVG PVVSFRLVYD
60 70 80 90 100
RETGKPKGYG FCEYQDQETA LSAMRNLNGR EFSGRALRVD NAASEKNKEE
110 120 130 140 150
LKSLGTGAPV IESPYGESIS PEDAPESISK AVASLPPEQM FELMKQMKLC
160 170 180 190 200
VQNSPQEARN MLLQNPQLAY ALLQAQVVMR IVDPEIALKI LHRQTNIPTL
210 220 230 240 250
ISGNPQPVHV AGPGSGPNVS MNQQNPQAPQ AQSLGGMHVN GAPPMMQASM
260 270 280 290 300
PGGVPAPVQM AAAVGGPGPG SLAPAGVMQA QVGMQGAGPV PMERGQVPMQ
310 320 330 340 350
DPRAAMQRGA LPTNVPTPRG LLGDAPNDPR GGTLMTVTGD VEPRAYLGPP
360 370 380 390 400
PPPHQGPPMH HVPGHEGRGP PPHDMRGGPL AEPRPLMAEP RGPMLDQRGP
410 420 430 440 450
PLDARGGRDP RGLDARGMEA RAMEARGLDA RGLEARAMEA RAMEARAMEA
460 470 480 490 500
RAMEARAMEA RAMEARGMDT RGPVPGPRGP MPSGIQGPNP MNMGAVVPQG
510 520 530 540 550
SRQVPVMQGA GMQGASMQGG SQPGGFSPGQ SQVTPQDHEK AALIMQVLQL
560 570 580
TADQIAMLPP EQRQSILILK EQIQKSTGAP
Length:580
Mass (Da):61,341
Last modified:July 19, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF61B2F5E5EAB1B7
GO
Isoform 2 (identifier: Q8BIQ5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     505-510: PVMQGA → MLVAYT
     511-580: Missing.

Show »
Length:510
Mass (Da):54,069
Checksum:iCADBF6928830A6A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2AEK1A2AEK1_MOUSE
AlphaCstF-64 variant 4
Cstf2
554Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6ZKC7F6ZKC7_MOUSE
Cleavage stimulation factor subunit...
Cstf2
259Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2AEK3A2AEK3_MOUSE
Cleavage stimulation factor subunit...
Cstf2
191Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2AEJ8A2AEJ8_MOUSE
Cleavage stimulation factor subunit...
Cstf2
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti299M → V in BAC28037 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_014844505 – 510PVMQGA → MLVAYT in isoform 2. 1 Publication6
Alternative sequenceiVSP_014845511 – 580Missing in isoform 2. 1 PublicationAdd BLAST70

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF317552 mRNA Translation: AAG31814.1
AK032817 mRNA Translation: BAC28037.1
AK088260 mRNA Translation: BAC40243.1
AL671915 Genomic DNA No translation available.
BC036719 mRNA Translation: AAH36719.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30389.1 [Q8BIQ5-1]
CCDS81170.1 [Q8BIQ5-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001277328.1, NM_001290399.1 [Q8BIQ5-2]
NP_573459.1, NM_133196.6 [Q8BIQ5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000033609; ENSMUSP00000033609; ENSMUSG00000031256 [Q8BIQ5-1]
ENSMUST00000113286; ENSMUSP00000108911; ENSMUSG00000031256 [Q8BIQ5-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
108062

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:108062

UCSC genome browser

More...
UCSCi
uc009ufi.2, mouse [Q8BIQ5-2]
uc009ufj.2, mouse [Q8BIQ5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF317552 mRNA Translation: AAG31814.1
AK032817 mRNA Translation: BAC28037.1
AK088260 mRNA Translation: BAC40243.1
AL671915 Genomic DNA No translation available.
BC036719 mRNA Translation: AAH36719.1
CCDSiCCDS30389.1 [Q8BIQ5-1]
CCDS81170.1 [Q8BIQ5-2]
RefSeqiNP_001277328.1, NM_001290399.1 [Q8BIQ5-2]
NP_573459.1, NM_133196.6 [Q8BIQ5-1]

3D structure databases

BMRBiQ8BIQ5
SMRiQ8BIQ5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi223801, 8 interactors
IntActiQ8BIQ5, 2 interactors
MINTiQ8BIQ5
STRINGi10090.ENSMUSP00000033609

PTM databases

iPTMnetiQ8BIQ5
PhosphoSitePlusiQ8BIQ5

2D gel databases

REPRODUCTION-2DPAGEiIPI00607981

Proteomic databases

EPDiQ8BIQ5
jPOSTiQ8BIQ5
PaxDbiQ8BIQ5
PeptideAtlasiQ8BIQ5
PRIDEiQ8BIQ5
ProteomicsDBi285381 [Q8BIQ5-1]
285382 [Q8BIQ5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
411, 330 antibodies

The DNASU plasmid repository

More...
DNASUi
108062

Genome annotation databases

EnsembliENSMUST00000033609; ENSMUSP00000033609; ENSMUSG00000031256 [Q8BIQ5-1]
ENSMUST00000113286; ENSMUSP00000108911; ENSMUSG00000031256 [Q8BIQ5-2]
GeneIDi108062
KEGGimmu:108062
UCSCiuc009ufi.2, mouse [Q8BIQ5-2]
uc009ufj.2, mouse [Q8BIQ5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1478
MGIiMGI:1343054, Cstf2

Phylogenomic databases

eggNOGiKOG0108, Eukaryota
GeneTreeiENSGT00940000158987
InParanoidiQ8BIQ5
OMAiASHYNSQ
OrthoDBi1455080at2759
PhylomeDBiQ8BIQ5
TreeFamiTF314948

Enzyme and pathway databases

ReactomeiR-MMU-72163, mRNA Splicing - Major Pathway
R-MMU-72187, mRNA 3'-end processing
R-MMU-73856, RNA Polymerase II Transcription Termination
R-MMU-77595, Processing of Intronless Pre-mRNAs

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
108062, 10 hits in 54 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cstf2, mouse

Protein Ontology

More...
PROi
PR:Q8BIQ5
RNActiQ8BIQ5, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000031256, Expressed in ventromedial nucleus of hypothalamus and 311 other tissues
ExpressionAtlasiQ8BIQ5, baseline and differential
GenevisibleiQ8BIQ5, MM

Family and domain databases

Gene3Di1.10.20.70, 1 hit
3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR033105, CSTF2
IPR038192, CSTF2_C_sf
IPR025742, CSTF2_hinge
IPR026896, CSTF_C
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
PANTHERiPTHR45735:SF6, PTHR45735:SF6, 1 hit
PfamiView protein in Pfam
PF14327, CSTF2_hinge, 1 hit
PF14304, CSTF_C, 1 hit
PF00076, RRM_1, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 1 hit
SUPFAMiSSF54928, SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102, RRM, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCSTF2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BIQ5
Secondary accession number(s): A2AEJ9
, A2AEK0, Q8K1Y6, Q9ERC2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: June 2, 2021
This is version 145 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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