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UniProtKB - Q8BIH0 (SP130_MOUSE)

Entry version 126 (17 Jun 2020)
Sequence version 2 (03 Apr 2007)
Previous versions | rss
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Protein

Histone deacetylase complex subunit SAP130

Gene

Sap130

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Histone deacetylase complex subunit SAP130
Alternative name(s):
130 kDa Sin3-associated polypeptide
Sin3-associated polypeptide p130
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sap130
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1919782 Sap130

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002837371 – 1057Histone deacetylase complex subunit SAP130Add BLAST1057

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei206Omega-N-methylarginineBy similarity1
Modified residuei329PhosphothreonineBy similarity1
Modified residuei416PhosphoserineCombined sources1
Modified residuei439PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki794Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei864PhosphoserineBy similarity1
Modified residuei865PhosphothreonineBy similarity1
Cross-linki873Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki878Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei884PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Acetylated.By similarity
Sumoylated with SUMO1.By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q8BIH0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8BIH0

PeptideAtlas

More...PeptideAtlasi		Q8BIH0

PRoteomics IDEntifications database

More...PRIDEi		Q8BIH0

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8BIH0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8BIH0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8BIH0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2 (By similarity).

Interacts (released by dead or dying cells) with CLEC4E.

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		234593, 7 interactors

Protein interaction database and analysis system

More...IntActi		Q8BIH0, 2 interactors

Molecular INTeraction database

More...MINTi		Q8BIH0

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000136842

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8BIH0 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni845 – 1057Interactions with SIN3A and HDAC1By similarityAdd BLAST213

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi56 – 143Pro-richAdd BLAST88
Compositional biasi208 – 212Poly-Ala5
Compositional biasi718 – 845Pro-richAdd BLAST128

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminus may interact with a transcriptional coactivator.By similarity
The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SAP130 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IJKN Eukaryota
ENOG410ZRAM LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00440000037733

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8BIH0

KEGG Orthology (KO)

More...KOi		K19192

Database of Orthologous Groups

More...OrthoDBi		242848at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8BIH0

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR024137 His_deAcase_cplx_SAP130
IPR031963 SAP130_C

The PANTHER Classification System

More...PANTHERi		PTHR13497 PTHR13497, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF16014 SAP130_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BIH0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSQQFPRLG TPSPGLSQPP SQIASSGSAG LINQVATVND EAGRDADVGT 
        60         70         80         90        100
REHVGPSSSL PPREEKQEPV VVRPYPQVQM LPAHHAVASA TPVAVTAPPA 
       110        120        130        140        150
HLTPAVPLSF SEGLMKPPPK PTMPSRPIAP APPSTMSLPP KVPGQVTVTM 
       160        170        180        190        200
ESSIPQASAI PVATISGQQG HPSNLHHIMT TNVQMSIIRS NAPGPPLHIG 
       210        220        230        240        250
ASHLPRGAAA AAVMSSSKVT TVLRPTSQLP NAATAQPAVQ HLIHQPIQSR 
       260        270        280        290        300
PPVTTSSTIP PAVVATVSAT RAQSPVITTT AAHAADSTLS RPTLSIQHPP 
       310        320        330        340        350
SAAISIQRPA QSRDVTTRIT LPSHPALGTP KQQLHTMAQK TIFSTGTPVA 
       360        370        380        390        400
AATVAPILAT NTLPSTTTAG SVSHTQAPTS TIVTMTMPSH SSHATAVTTS 
       410        420        430        440        450
NIPVAKVVPQ QITHTSPRIQ PDYPPERSSL IPISGHRASP NPVAMETRND 
       460        470        480        490        500
NRPSVPVQFQ YFLPTYPPSA YPLAAHTYTP ITSSVSTIRQ YPVSAQAPNS 
       510        520        530        540        550
TITAQTGVGV ASTVHLNPMQ LMTVDASHAR HIQGIQPAPI STQGIQPAPI 
       560        570        580        590        600
GTSGIQPAPI GTPGIHSAAP INTQGLQPAA MANQQPQPEG KTSAVVLADG 
       610        620        630        640        650
ATIVANPISN PFSAAPAATT VVQTHSQSAS TNTPAQGSSP RPSILRKKPA 
       660        670        680        690        700
TDGMAVRKTL LPPQPPDVAT PRVESSMRSA SGSPRPAGAK PKSEVHVSIA 
       710        720        730        740        750
TPVTVSLETI SNQNAEQPTV AVPPTAQQPP PTIPSMIAAA SPPSQPAIAL 
       760        770        780        790        800
STIPGAVPVT PPITTIAATP TLSAPVGGTP STVLGPPVPE IKVKEEAEPV 
       810        820        830        840        850
DITRPVSTVP PLATNTVSPS LALLASNLSM PPSDLPPGAS PRKKPRKQQH 
       860        870        880        890        900
VISTEEGDMM ETNSTDDEKS AAKSLLVKAE KRKSPPKEYI DEEGVRYVPV 
       910        920        930        940        950
RPRPPITLLR HYRNPWKAAY HHFQRYSDVR VKEEKKAMLQ EIANQKGVSC 
       960        970        980        990       1000
RAQGWKVHLC AAQLLQLTNL EHDVYERLTN LQEGIIPKKK AATDDDLHRI 
      1010       1020       1030       1040       1050
NELIQGNMQR CKLVMDQISE ARDSMLKVLD HKDRVLKLLN KNGTVKKVSK 

LKRKEKV
Length:1,057
Mass (Da):111,228
Last modified:April 3, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9D963F4CD53B971A
GO
Isoform 2 (identifier: Q8BIH0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-178: Missing.

Show »
Length:879
Mass (Da):92,892
Checksum:iF7AC76706F802240
GO
Isoform 3 (identifier: Q8BIH0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     340-348: KTIFSTGTP → VRTVTPPEG
     349-1057: Missing.

Show »
Length:348
Mass (Da):35,934
Checksum:iC8FD4A7762B765FA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J060A0A0R4J060_MOUSE
Histone deacetylase complex subunit...
Sap130
1,056Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QNK5J3QNK5_MOUSE
Histone deacetylase complex subunit...
Sap130
1,057Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q4EC23A0A3Q4EC23_MOUSE
Histone deacetylase complex subunit...
Sap130
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q4EGN6A0A3Q4EGN6_MOUSE
Histone deacetylase complex subunit...
Sap130
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH66030 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti594Missing in BAC35469 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0243571 – 178Missing in isoform 2. 1 PublicationAdd BLAST178
Alternative sequenceiVSP_024358340 – 348KTIFSTGTP → VRTVTPPEG in isoform 3. 1 Publication9
Alternative sequenceiVSP_024359349 – 1057Missing in isoform 3. 1 PublicationAdd BLAST709

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK011978 mRNA Translation: BAB27953.1
AK053675 mRNA Translation: BAC35469.1
AK084078 mRNA Translation: BAC39113.1
BC063075 mRNA Translation: AAH63075.1
BC066030 mRNA Translation: AAH66030.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS89207.1 [Q8BIH0-1]

NCBI Reference Sequences

More...RefSeqi		NP_766553.1, NM_172965.2
XP_006526014.1, XM_006525951.2 [Q8BIH0-1]
XP_006526015.1, XM_006525952.3 [Q8BIH0-1]
XP_006526017.1, XM_006525954.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000235017; ENSMUSP00000157127; ENSMUSG00000024260 [Q8BIH0-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		269003

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:269003

UCSC genome browser

More...UCSCi		uc008eib.1 mouse [Q8BIH0-1]
uc008eie.1 mouse [Q8BIH0-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011978 mRNA Translation: BAB27953.1
AK053675 mRNA Translation: BAC35469.1
AK084078 mRNA Translation: BAC39113.1
BC063075 mRNA Translation: AAH63075.1
BC066030 mRNA Translation: AAH66030.1 Different initiation.
CCDSiCCDS89207.1 [Q8BIH0-1]
RefSeqiNP_766553.1, NM_172965.2
XP_006526014.1, XM_006525951.2 [Q8BIH0-1]
XP_006526015.1, XM_006525952.3 [Q8BIH0-1]
XP_006526017.1, XM_006525954.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi234593, 7 interactors
IntActiQ8BIH0, 2 interactors
MINTiQ8BIH0
STRINGi10090.ENSMUSP00000136842

PTM databases

iPTMnetiQ8BIH0
PhosphoSitePlusiQ8BIH0

Proteomic databases

jPOSTiQ8BIH0
PaxDbiQ8BIH0
PeptideAtlasiQ8BIH0
PRIDEiQ8BIH0

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33473 145 antibodies

Genome annotation databases

EnsembliENSMUST00000235017; ENSMUSP00000157127; ENSMUSG00000024260 [Q8BIH0-1]
GeneIDi269003
KEGGimmu:269003
UCSCiuc008eib.1 mouse [Q8BIH0-1]
uc008eie.1 mouse [Q8BIH0-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79595
MGIiMGI:1919782 Sap130

Phylogenomic databases

eggNOGiENOG410IJKN Eukaryota
ENOG410ZRAM LUCA
GeneTreeiENSGT00440000037733
InParanoidiQ8BIH0
KOiK19192
OrthoDBi242848at2759
PhylomeDBiQ8BIH0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		269003 6 hits in 12 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Sap130 mouse

Protein Ontology

More...PROi		PR:Q8BIH0
RNActiQ8BIH0 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

ExpressionAtlasiQ8BIH0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR024137 His_deAcase_cplx_SAP130
IPR031963 SAP130_C
PANTHERiPTHR13497 PTHR13497, 1 hit
PfamiView protein in Pfam
PF16014 SAP130_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSP130_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BIH0
Secondary accession number(s): Q6NZP5
, Q6P553, Q8BID9, Q9CSU1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 17, 2020
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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