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Protein

Paraneoplastic antigen Ma2 homolog

Gene

Pnma2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Paraneoplastic antigen Ma2 homolog
Gene namesi
Name:Pnma2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:2444129 Pnma2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001552042 – 365Paraneoplastic antigen Ma2 homologAdd BLAST364

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ8BHK0
PRIDEiQ8BHK0

PTM databases

PhosphoSitePlusiQ8BHK0

Expressioni

Tissue specificityi

Expressed in the cerebrum, cerebellum and testis.1 Publication

Gene expression databases

BgeeiENSMUSG00000046204 Expressed in 126 organ(s), highest expression level in ventromedial nucleus of hypothalamus
CleanExiMM_PNMA2
GenevisibleiQ8BHK0 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000086646

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi333 – 338Poly-Glu6

Sequence similaritiesi

Belongs to the PNMA family.Curated

Phylogenomic databases

eggNOGiENOG410J6QQ Eukaryota
ENOG410Y05Y LUCA
GeneTreeiENSGT00530000062986
HOVERGENiHBG052488
InParanoidiQ8BHK0
OMAiFKTPNQD
OrthoDBiEOG091G0BG9
TreeFamiTF335054

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
IPR026525 PNMA2
PANTHERiPTHR23095 PTHR23095, 1 hit
PTHR23095:SF16 PTHR23095:SF16, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8BHK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVALLEEWC KIMGVDVQKS LLVVDIPVDC GEPEIQTVLQ EALKCVGSYR
60 70 80 90 100
LLGKIFQKQD NTSVVLVELM EDTDMSVVPS EVQGKGGVWK VIFKTPNQDT
110 120 130 140 150
EFLQRLNLFL EKEGQTVAGM FRALKHEGVS PATPPCTSPE LLAHLTGQAM
160 170 180 190 200
VHGQRPLLPV KYCKMRIFSG STAAAPEEEP FEVWLEQATE IAKEWPIPEA
210 220 230 240 250
EKKRWVAESL RGPALDLMHI VQADNPSISV GECLEAFKQV FGSTESRRTS
260 270 280 290 300
QVKYLRTYQQ EGEKISAYVL RLETLLRRAV EKRAIPRNIA DQVRLEQVMA
310 320 330 340 350
GANLGNVLWC RLQELKDQGP LPTFLQLMKV IREEEEEEDA YFEQESREEP
360
GEREGSGCWN NSRNN
Length:365
Mass (Da):41,201
Last modified:March 1, 2003 - v1
Checksum:i0F90C940B9D843D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK043718 mRNA Translation: BAC31626.1
AK043910 mRNA Translation: BAC31700.1
BC065116 mRNA Translation: AAH65116.1
CCDSiCCDS27226.1
RefSeqiNP_780707.1, NM_175498.4
XP_006519052.1, XM_006518989.3
XP_006519053.1, XM_006518990.3
UniGeneiMm.44358

Genome annotation databases

EnsembliENSMUST00000089236; ENSMUSP00000086646; ENSMUSG00000046204
ENSMUST00000122431; ENSMUSP00000112629; ENSMUSG00000046204
GeneIDi239157
KEGGimmu:239157
UCSCiuc007ukq.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK043718 mRNA Translation: BAC31626.1
AK043910 mRNA Translation: BAC31700.1
BC065116 mRNA Translation: AAH65116.1
CCDSiCCDS27226.1
RefSeqiNP_780707.1, NM_175498.4
XP_006519052.1, XM_006518989.3
XP_006519053.1, XM_006518990.3
UniGeneiMm.44358

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000086646

PTM databases

PhosphoSitePlusiQ8BHK0

Proteomic databases

PaxDbiQ8BHK0
PRIDEiQ8BHK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000089236; ENSMUSP00000086646; ENSMUSG00000046204
ENSMUST00000122431; ENSMUSP00000112629; ENSMUSG00000046204
GeneIDi239157
KEGGimmu:239157
UCSCiuc007ukq.2 mouse

Organism-specific databases

CTDi10687
MGIiMGI:2444129 Pnma2

Phylogenomic databases

eggNOGiENOG410J6QQ Eukaryota
ENOG410Y05Y LUCA
GeneTreeiENSGT00530000062986
HOVERGENiHBG052488
InParanoidiQ8BHK0
OMAiFKTPNQD
OrthoDBiEOG091G0BG9
TreeFamiTF335054

Miscellaneous databases

ChiTaRSiPnma2 mouse
PROiPR:Q8BHK0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046204 Expressed in 126 organ(s), highest expression level in ventromedial nucleus of hypothalamus
CleanExiMM_PNMA2
GenevisibleiQ8BHK0 MM

Family and domain databases

InterProiView protein in InterPro
IPR026523 PNMA
IPR026525 PNMA2
PANTHERiPTHR23095 PTHR23095, 1 hit
PTHR23095:SF16 PTHR23095:SF16, 1 hit
PfamiView protein in Pfam
PF14893 PNMA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPNMA2_MOUSE
AccessioniPrimary (citable) accession number: Q8BHK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2003
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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