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Entry version 141 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Polypyrimidine tract-binding protein 3

Gene

Ptbp3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U) (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor, RNA-binding
Biological processDifferentiation, Erythrocyte maturation, mRNA processing, mRNA splicing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polypyrimidine tract-binding protein 3
Alternative name(s):
Regulator of differentiation 1
Short name:
Rod1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ptbp3
Synonyms:Rod1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923334, Ptbp3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000818741 – 523Polypyrimidine tract-binding protein 3Add BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki36Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei98PhosphotyrosineBy similarity1
Modified residuei109PhosphothreonineBy similarity1
Cross-linki187Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei394N6-acetyllysineBy similarity1
Modified residuei425PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8BHD7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8BHD7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BHD7

PeptideAtlas

More...
PeptideAtlasi
Q8BHD7

PRoteomics IDEntifications database

More...
PRIDEi
Q8BHD7

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q8BHD7-1 [Q8BHD7-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BHD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BHD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028382, Expressed in blood and 311 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BHD7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BHD7, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with THBS4 (via the acidic amphipathic C-terminus).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
230952, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q8BHD7, 1 interactor

Molecular INTeraction database

More...
MINTi
Q8BHD7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000099947

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BHD7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BHD7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 114RRM 1PROSITE-ProRule annotationAdd BLAST85
Domaini153 – 229RRM 2PROSITE-ProRule annotationAdd BLAST77
Domaini329 – 403RRM 3PROSITE-ProRule annotationAdd BLAST75
Domaini446 – 521RRM 4PROSITE-ProRule annotationAdd BLAST76

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1190, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00990000203573

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BHD7

KEGG Orthology (KO)

More...
KOi
K17844

Database of Orthologous Groups

More...
OrthoDBi
1545178at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BHD7

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12779, RRM1_ROD1, 1 hit
cd12693, RRM2_PTBP1_like, 1 hit
cd12703, RRM4_ROD1, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006536, HnRNP-L/PTB
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR034798, PTBP1/2/3_RRM2
IPR021790, PTBP1_RRM
IPR033110, PTBP3_RRM4
IPR035979, RBD_domain_sf
IPR034326, ROD1_RRM1
IPR000504, RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076, RRM_1, 1 hit
PF11835, RRM_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 3 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01649, hnRNP-L_PTB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102, RRM, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BHD7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNSSTSAGVY ANGNDNKKFK GDRPPCSPSR VLHLRKIPCD VTEAEVISLG
60 70 80 90 100
LPFGKVTNLL MLKGKSQAFL EMASEEAAVT MINYYTPVTP HLRSQPVYIQ
110 120 130 140 150
YSNHRELKTD NLPNQARAQA ALQAVSAVQS GNLSLPGATA NEGTLLPGQS
160 170 180 190 200
PVLRIIIENL FYPVTLEVLH QIFSKFGTVL KIITFTKNNQ FQALLQYADP
210 220 230 240 250
VNAQYAKMAL DGQNIYNACC TLRIDFSKLT SLNVKYNNDK SRDFTRLDLP
260 270 280 290 300
TGDGQPSLEP PMAAAFGAPG IMSSPYAGAA GFAPAIAFPQ AAGLSVPAVP
310 320 330 340 350
GALGPLTLTS SAVSGRMAIP GASGMPGNSV LLVTNLNPDF ITPHGLFILF
360 370 380 390 400
GVYGDVHRVK IMFNKKENAL VQMADASQAQ LAMNHLSGQR LYGKVLRATL
410 420 430 440 450
SKHQAVQLPR EGQEDQGLTK DFSNSPLHRF KKPGSKNFQN IFPPSATLHL
460 470 480 490 500
SNIPPSVTMD DLKNLFTEAG CSVKAFKFFQ KDRKMALIQL GSVEEAIQAL
510 520
IELHNHDLGE NHHLRVSFSK STI
Length:523
Mass (Da):56,701
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2CED3B84B745AA25
GO
Isoform 2 (identifier: Q8BHD7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     8-10: Missing.

Show »
Length:520
Mass (Da):56,382
Checksum:i8041064497B7D04E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G8JL74G8JL74_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
551Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UXA6G3UXA6_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
554Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZ01G3UZ01_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
457Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7C521F7C521_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UXZ8G3UXZ8_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UY95G3UY95_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UXZ6G3UXZ6_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3UZG7G3UZG7_MOUSE
Polypyrimidine tract-binding protei...
Ptbp3 Rod1
41Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0108698 – 10Missing in isoform 2. 1 Publication3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK033732 mRNA Translation: BAC28453.1
AK088560 mRNA Translation: BAC40425.1
AL824704 Genomic DNA No translation available.
BC006638 mRNA Translation: AAH06638.1
BC057641 mRNA Translation: AAH57641.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18221.1 [Q8BHD7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_659153.2, NM_144904.2
NP_835458.1, NM_178164.3 [Q8BHD7-1]
XP_006537917.1, XM_006537854.3 [Q8BHD7-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030076; ENSMUSP00000030076; ENSMUSG00000028382 [Q8BHD7-1]
ENSMUST00000148331; ENSMUSP00000122840; ENSMUSG00000028382 [Q8BHD7-2]
ENSMUST00000172768; ENSMUSP00000134102; ENSMUSG00000028382 [Q8BHD7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
230257

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:230257

UCSC genome browser

More...
UCSCi
uc008szx.2, mouse [Q8BHD7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033732 mRNA Translation: BAC28453.1
AK088560 mRNA Translation: BAC40425.1
AL824704 Genomic DNA No translation available.
BC006638 mRNA Translation: AAH06638.1
BC057641 mRNA Translation: AAH57641.1
CCDSiCCDS18221.1 [Q8BHD7-1]
RefSeqiNP_659153.2, NM_144904.2
NP_835458.1, NM_178164.3 [Q8BHD7-1]
XP_006537917.1, XM_006537854.3 [Q8BHD7-2]

3D structure databases

SMRiQ8BHD7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230952, 4 interactors
IntActiQ8BHD7, 1 interactor
MINTiQ8BHD7
STRINGi10090.ENSMUSP00000099947

PTM databases

iPTMnetiQ8BHD7
PhosphoSitePlusiQ8BHD7

Proteomic databases

EPDiQ8BHD7
jPOSTiQ8BHD7
PaxDbiQ8BHD7
PeptideAtlasiQ8BHD7
PRIDEiQ8BHD7
TopDownProteomicsiQ8BHD7-1 [Q8BHD7-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29656, 152 antibodies

Genome annotation databases

EnsembliENSMUST00000030076; ENSMUSP00000030076; ENSMUSG00000028382 [Q8BHD7-1]
ENSMUST00000148331; ENSMUSP00000122840; ENSMUSG00000028382 [Q8BHD7-2]
ENSMUST00000172768; ENSMUSP00000134102; ENSMUSG00000028382 [Q8BHD7-2]
GeneIDi230257
KEGGimmu:230257
UCSCiuc008szx.2, mouse [Q8BHD7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9991
MGIiMGI:1923334, Ptbp3

Phylogenomic databases

eggNOGiKOG1190, Eukaryota
GeneTreeiENSGT00990000203573
InParanoidiQ8BHD7
KOiK17844
OrthoDBi1545178at2759
PhylomeDBiQ8BHD7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
230257, 2 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Ptbp3, mouse

Protein Ontology

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PROi
PR:Q8BHD7
RNActiQ8BHD7, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000028382, Expressed in blood and 311 other tissues
ExpressionAtlasiQ8BHD7, baseline and differential
GenevisibleiQ8BHD7, MM

Family and domain databases

CDDicd12779, RRM1_ROD1, 1 hit
cd12693, RRM2_PTBP1_like, 1 hit
cd12703, RRM4_ROD1, 1 hit
Gene3Di3.30.70.330, 4 hits
InterProiView protein in InterPro
IPR006536, HnRNP-L/PTB
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR034798, PTBP1/2/3_RRM2
IPR021790, PTBP1_RRM
IPR033110, PTBP3_RRM4
IPR035979, RBD_domain_sf
IPR034326, ROD1_RRM1
IPR000504, RRM_dom
PfamiView protein in Pfam
PF00076, RRM_1, 1 hit
PF11835, RRM_8, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 4 hits
SUPFAMiSSF54928, SSF54928, 3 hits
TIGRFAMsiTIGR01649, hnRNP-L_PTB, 1 hit
PROSITEiView protein in PROSITE
PS50102, RRM, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTBP3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BHD7
Secondary accession number(s): A2ANH0, A2ANH1, Q923C3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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