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UniProtKB - Q8BH76 (Q8BH76_MOUSE)
Protein
DNA polymerase delta subunit 3
Gene
Pold3
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Biological processi
- DNA replication Source: UniProtKB-KW
Keywordsi
Biological process | DNA replicationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: DNA polymerase delta subunit 3ARBA annotation |
Gene namesi | Name:Pold3Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1915217, Pold3 |
VEuPathDBi | HostDB:ENSMUSG00000030726 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- delta DNA polymerase complex Source: InterPro
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000030726, Expressed in secondary oocyte and 317 other tissues |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 144 – 186 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 200 – 230 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 254 – 383 | DisorderedSequence analysisAdd BLAST | 130 | |
Regioni | 402 – 461 | DisorderedSequence analysisAdd BLAST | 60 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 150 – 186 | Polar residuesSequence analysisAdd BLAST | 37 | |
Compositional biasi | 283 – 315 | Basic and acidic residuesSequence analysisAdd BLAST | 33 | |
Compositional biasi | 344 – 365 | Pro residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 402 – 417 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 425 – 441 | Basic and acidic residuesSequence analysisAdd BLAST | 17 |
Phylogenomic databases
GeneTreei | ENSGT01010000222805 |
HOGENOMi | CLU_047571_0_0_1 |
OMAi | GIMQSFA |
TreeFami | TF103006 |
Family and domain databases
Gene3Di | 3.90.1030.20, 1 hit |
InterProi | View protein in InterPro IPR019038, POLD3 IPR041913, POLD3_sf |
PANTHERi | PTHR17598, PTHR17598, 1 hit |
Pfami | View protein in Pfam PF09507, CDC27, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
Q8BH76-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEQLYLENI DEFVTDQNKI VTYKWLSYTL GVHVNQAKQM LYEYVERKRK
60 70 80 90 100
ENSGAQLHVT YLVSGSLIQN GHSCHKVAVV REDKLEAVKS KLAVTASIHV
110 120 130 140 150
YSIQKAMLKD SGPLFNTDYD ILKSNLQNCS KFSAIQCAAA VPRAPAESPS
160 170 180 190 200
SRKYEQSNLQ AASEAQASEL TTNGHGPPAS KQASQQPKGI MGMLISKAAT
210 220 230 240 250
KTQDTNKETK PEAREVTSAS SAGGKAPGKG SVMSNFFGKA AMNKLKVNLD
260 270 280 290 300
SEQAVKEEKT VEQPPVSVTE PKLAAPPAQK KSSRKSEPGK VQQKEKSRGK
310 320 330 340 350
RVDLSDEEAK ETEHLKKKRR RIKLPQSDSS EDEVFEDSPE MYEADSPSPP
360 370 380 390 400
PVSPPPDPMP KTEPPPVKRS SGETKRRRKR VLKSKTFVDE EGCIVTEKVY
410 420 430 440 450
ESESCTDSEE ELKMKPASAH KPPAAAVKRE PREERKGPKK GAAALGKANR
460
QVSITGFFQK K
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9EQ28 | DPOD3_MOUSE | DNA polymerase delta subunit 3 | Pold3 | 462 | Annotation score: | ||
A0A140LHY7 | A0A140LHY7_MOUSE | DNA polymerase delta subunit 3 | Pold3 | 422 | Annotation score: | ||
D6RG54 | D6RG54_MOUSE | DNA polymerase delta subunit 3 | Pold3 | 44 | Annotation score: | ||
A0A140LHJ0 | A0A140LHJ0_MOUSE | DNA polymerase delta subunit 3 | Pold3 | 86 | Annotation score: | ||
A0A140LIW6 | A0A140LIW6_MOUSE | DNA polymerase delta subunit 3 | Pold3 | 269 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC055325 mRNA Translation: AAH55325.1 AK031778 mRNA Translation: BAC27544.1 AK088385 mRNA Translation: BAC40320.1 |
RefSeqi | NP_598453.1, NM_133692.2 |
Genome annotation databases
Ensembli | ENSMUST00000032969; ENSMUSP00000032969; ENSMUSG00000030726 |
GeneIDi | 67967 |
UCSCi | uc009imj.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC055325 mRNA Translation: AAH55325.1 AK031778 mRNA Translation: BAC27544.1 AK088385 mRNA Translation: BAC40320.1 |
RefSeqi | NP_598453.1, NM_133692.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
ProteomicsDBi | 343041 |
Protocols and materials databases
DNASUi | 67967 |
Genome annotation databases
Ensembli | ENSMUST00000032969; ENSMUSP00000032969; ENSMUSG00000030726 |
GeneIDi | 67967 |
UCSCi | uc009imj.1, mouse |
Organism-specific databases
CTDi | 10714 |
MGIi | MGI:1915217, Pold3 |
VEuPathDBi | HostDB:ENSMUSG00000030726 |
Phylogenomic databases
GeneTreei | ENSGT01010000222805 |
HOGENOMi | CLU_047571_0_0_1 |
OMAi | GIMQSFA |
TreeFami | TF103006 |
Miscellaneous databases
BioGRID-ORCSi | 67967, 24 hits in 97 CRISPR screens |
ChiTaRSi | Pold3, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030726, Expressed in secondary oocyte and 317 other tissues |
Family and domain databases
Gene3Di | 3.90.1030.20, 1 hit |
InterProi | View protein in InterPro IPR019038, POLD3 IPR041913, POLD3_sf |
PANTHERi | PTHR17598, PTHR17598, 1 hit |
Pfami | View protein in Pfam PF09507, CDC27, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8BH76_MOUSE | |
Accessioni | Q8BH76Primary (citable) accession number: Q8BH76 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | January 19, 2022 | |
This is version 135 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |