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Entry version 112 (02 Jun 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Transmembrane and coiled-coil domain-containing protein 3

Gene

Tmco3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable Na+/H+ antiporter.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiport, Ion transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane and coiled-coil domain-containing protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tmco3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444946, Tmco3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei317 – 337HelicalSequence analysisAdd BLAST21
Transmembranei350 – 370HelicalSequence analysisAdd BLAST21
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Transmembranei499 – 519HelicalSequence analysisAdd BLAST21
Transmembranei555 – 575HelicalSequence analysisAdd BLAST21
Transmembranei579 – 599HelicalSequence analysisAdd BLAST21
Transmembranei609 – 629HelicalSequence analysisAdd BLAST21
Transmembranei641 – 661HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024985723 – 678Transmembrane and coiled-coil domain-containing protein 3Add BLAST656

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi174N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi206N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi230N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BH01

PeptideAtlas

More...
PeptideAtlasi
Q8BH01

PRoteomics IDEntifications database

More...
PRIDEi
Q8BH01

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
259421 [Q8BH01-1]
259422 [Q8BH01-2]
259423 [Q8BH01-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q8BH01, 3 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8BH01

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BH01

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000038497, Expressed in cardiac ventricle and 287 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8BH01, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BH01, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000040347

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BH01, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BH01

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili124 – 204Sequence analysisAdd BLAST81

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coil, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1650, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001394

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_026093_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BH01

Identification of Orthologs from Complete Genome Data

More...
OMAi
YSSIVME

Database of Orthologous Groups

More...
OrthoDBi
522572at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BH01

TreeFam database of animal gene trees

More...
TreeFami
TF329364

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006153, Cation/H_exchanger
IPR038770, Na+/solute_symporter_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00999, Na_H_Exchanger, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8BH01-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKVLDQSLLW MLLPFFHLIA SAAEHEEVAK HAIKLHRGKG ATATQRKQWA
60 70 80 90 100
LDSCRRLTGL LRQKNVVLNK LKNAIRAVEK DTSLSGEEKL FQVHTFEIFQ
110 120 130 140 150
KELNESENSI FQAIYGLQRA LQGDYRDVVN MKESSKQRLE ALREAAIKEE
160 170 180 190 200
TEYVELLAAE KHQVEALKNM QHQNKSLSML DEILEDVRKA ADRLEEEIEE
210 220 230 240 250
HAFDDNKSVK GVNFEAVLRV EEEEASSKQN MTKREVEDGL GLSMLIDSQN
260 270 280 290 300
NQYILTKPRD STIPRADHHF IKDIVTIGML SLPCGWLCTA IGLPTMFGYI
310 320 330 340 350
ICGVLLGPSG LNSIKSIVQV ETLGEFGVFF TLFLVGLEFS PEKLRKVWRI
360 370 380 390 400
SLQGPCYMTL LMIAFGLWWG HLLRIRPTQS VFISTCLSLS STPLVSRFLV
410 420 430 440 450
GSARGDKEAG DIDYSTVLLG MLVMQDVQLG LFIAVMPTLI QAGAGASSSV
460 470 480 490 500
VMEVLRILFL IGQILFSLAA VFLLCLVMKT YLIGPYYRKL HLESKGNKEI
510 520 530 540 550
LVLGVSAFTF LMLTVTELLD VSMELGCFLA GALVSSQGHM VTEEIMTYIE
560 570 580 590 600
PIRDFLAIIF FASIGLHVFP TFVIYELTVL VFLTLSVVIM KFVLAVLVLS
610 620 630 640 650
LILPRSSQYI KWIVSAGLAQ VSEFSFVLGS RARRAGILSR EVYLLILSVT
660 670
TLSLLLAPVL WKAAITKCVP RPERRSSL
Length:678
Mass (Da):75,903
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5DCFBE9A9112FF4F
GO
Isoform 2 (identifier: Q8BH01-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     409-409: Missing.

Show »
Length:677
Mass (Da):75,832
Checksum:i8955B96136606631
GO
Isoform 3 (identifier: Q8BH01-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     316-328: SIVQVETLGEFGV → EVTGAASESSSHH
     329-678: Missing.

Show »
Length:328
Mass (Da):37,022
Checksum:i3C8A725B20FB4887
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GT23A0A1B0GT23_MOUSE
Transmembrane and coiled-coil domai...
Tmco3
237Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti79E → G in BAE28438 (PubMed:16141072).Curated1
Sequence conflicti186D → G in AAH53487 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_020565316 – 328SIVQV…GEFGV → EVTGAASESSSHH in isoform 3. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_020566329 – 678Missing in isoform 3. 1 PublicationAdd BLAST350
Alternative sequenceiVSP_020567409Missing in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK033499 mRNA Translation: BAC28322.1
AK046065 mRNA Translation: BAC32588.1
AK049974 mRNA Translation: BAC34013.1
AK088866 mRNA Translation: BAC40623.1
AK148252 mRNA Translation: BAE28438.1
BC026890 mRNA Translation: AAH26890.1
BC039955 mRNA Translation: AAH39955.1
BC053487 mRNA Translation: AAH53487.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40231.1 [Q8BH01-1]

NCBI Reference Sequences

More...
RefSeqi
NP_758486.1, NM_172282.2 [Q8BH01-1]
XP_006508825.1, XM_006508762.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000045229; ENSMUSP00000040347; ENSMUSG00000038497 [Q8BH01-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
234076

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:234076

UCSC genome browser

More...
UCSCi
uc009kxm.1, mouse [Q8BH01-3]
uc009kxn.1, mouse [Q8BH01-1]
uc009kxo.1, mouse [Q8BH01-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033499 mRNA Translation: BAC28322.1
AK046065 mRNA Translation: BAC32588.1
AK049974 mRNA Translation: BAC34013.1
AK088866 mRNA Translation: BAC40623.1
AK148252 mRNA Translation: BAE28438.1
BC026890 mRNA Translation: AAH26890.1
BC039955 mRNA Translation: AAH39955.1
BC053487 mRNA Translation: AAH53487.1
CCDSiCCDS40231.1 [Q8BH01-1]
RefSeqiNP_758486.1, NM_172282.2 [Q8BH01-1]
XP_006508825.1, XM_006508762.2

3D structure databases

SMRiQ8BH01
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040347

PTM databases

GlyGeniQ8BH01, 3 sites
iPTMnetiQ8BH01
PhosphoSitePlusiQ8BH01

Proteomic databases

PaxDbiQ8BH01
PeptideAtlasiQ8BH01
PRIDEiQ8BH01
ProteomicsDBi259421 [Q8BH01-1]
259422 [Q8BH01-2]
259423 [Q8BH01-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
25950, 63 antibodies

The DNASU plasmid repository

More...
DNASUi
234076

Genome annotation databases

EnsembliENSMUST00000045229; ENSMUSP00000040347; ENSMUSG00000038497 [Q8BH01-1]
GeneIDi234076
KEGGimmu:234076
UCSCiuc009kxm.1, mouse [Q8BH01-3]
uc009kxn.1, mouse [Q8BH01-1]
uc009kxo.1, mouse [Q8BH01-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55002
MGIiMGI:2444946, Tmco3

Phylogenomic databases

eggNOGiKOG1650, Eukaryota
GeneTreeiENSGT00390000001394
HOGENOMiCLU_026093_0_0_1
InParanoidiQ8BH01
OMAiYSSIVME
OrthoDBi522572at2759
PhylomeDBiQ8BH01
TreeFamiTF329364

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
234076, 3 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tmco3, mouse

Protein Ontology

More...
PROi
PR:Q8BH01
RNActiQ8BH01, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000038497, Expressed in cardiac ventricle and 287 other tissues
ExpressionAtlasiQ8BH01, baseline and differential
GenevisibleiQ8BH01, MM

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR006153, Cation/H_exchanger
IPR038770, Na+/solute_symporter_sf
PfamiView protein in Pfam
PF00999, Na_H_Exchanger, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMCO3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BH01
Secondary accession number(s): Q3UFX1
, Q7TMT5, Q8BGL4, Q8R303
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 19, 2006
Last sequence update: March 1, 2003
Last modified: June 2, 2021
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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