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Protein
Submitted name:

Cytochrome P450, family 4, subfamily f, polypeptide 39

Gene

Cyp4f39

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-MMU-211935 Fatty acids
R-MMU-211979 Eicosanoids
R-MMU-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 4, subfamily f, polypeptide 39Imported
Submitted name:
RIKEN cDNA 4732474A20, isoform CRA_bImported
Gene namesi
Name:Cyp4f39Imported
Synonyms:4732474A20RikImported
ORF Names:mCG_14252Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:2445210 Cyp4f39

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 40HelicalSequence analysisAdd BLAST21
Transmembranei95 – 112HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000061126 Expressed in 68 organ(s), highest expression level in ear

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003413

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140829
HOVERGENiHBG000182
KOiK00490
OMAiFNQCTDI
OrthoDBiEOG091G06KN
TreeFamiTF105088

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BGU0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPLTDYLLQ LLGLEKTAFR VYVVSALLLL VLFFFFRLLV RAFKLFSDFR
60 70 80 90 100
ITCRKLSCFP EPPGRHWLLG HMSMYLPNEK GLQNEKKVLD TMHHIILAWV
110 120 130 140 150
GPFLPLLVLV HPDYIKPVLG ASAAIAPKDE FFYSFLKPWL GDGLLISKGN
160 170 180 190 200
KWSRHRRLLT PAFHFDILKP YMKIFNQCTN IMHAKWRRHL AEGSVTSFDM
210 220 230 240 250
FEHISLMTLD SLQKCVFSYN SDCQERMSDY ISSIIELSAL VVRRQYRLHH
260 270 280 290 300
YLDFMYYLTA DGRRFRQACD TVHNFTTEVI QERRQALRQQ GAEAWLKAKQ
310 320 330 340 350
GKTLDFIDVL LLAKDEEGKE LSDEDIRAEA DTFMFEGHDT TSSGLSWALF
360 370 380 390 400
NLAKYPEYQE KCREEIQEVM KGRELEELDW DDLTQLPFTT MCIKESLRQF
410 420 430 440 450
PPVTLISRRC TEDIKLPDGR VIPKGIICLV SIYGTHHNPI VWPDSKVYNP
460 470 480 490 500
YRFDPDTPQQ RSPLAFVPFS AGPRNCIGQS FAMAEMRVVV ALTLLRFRLS
510 520 530
VDRTHKVRRK PELILRTENG LWLNVEPLPS RA
Length:532
Mass (Da):61,934
Last modified:March 1, 2003 - v1
Checksum:i705C310773091B16
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT485616 Genomic DNA No translation available.
AK028950 mRNA Translation: BAC26210.1
AK037192 mRNA Translation: BAC29745.1
CH466640 Genomic DNA Translation: EDL40309.1
RefSeqiNP_796281.1, NM_177307.3
XP_006524486.1, XM_006524423.3
UniGeneiMm.130900

Genome annotation databases

EnsembliENSMUST00000003413; ENSMUSP00000003413; ENSMUSG00000061126
GeneIDi320997
KEGGimmu:320997
UCSCiuc008bxe.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT485616 Genomic DNA No translation available.
AK028950 mRNA Translation: BAC26210.1
AK037192 mRNA Translation: BAC29745.1
CH466640 Genomic DNA Translation: EDL40309.1
RefSeqiNP_796281.1, NM_177307.3
XP_006524486.1, XM_006524423.3
UniGeneiMm.130900

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003413

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000003413; ENSMUSP00000003413; ENSMUSG00000061126
GeneIDi320997
KEGGimmu:320997
UCSCiuc008bxe.1 mouse

Organism-specific databases

CTDi320997
MGIiMGI:2445210 Cyp4f39

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140829
HOVERGENiHBG000182
KOiK00490
OMAiFNQCTDI
OrthoDBiEOG091G06KN
TreeFamiTF105088

Enzyme and pathway databases

ReactomeiR-MMU-211935 Fatty acids
R-MMU-211979 Eicosanoids
R-MMU-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX)

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000061126 Expressed in 68 organ(s), highest expression level in ear

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BGU0_MOUSE
AccessioniPrimary (citable) accession number: Q8BGU0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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