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UniProtKB - Q8BGS3 (ZKSC1_MOUSE)

Entry version 155 (23 Feb 2022)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
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Protein

Zinc finger protein with KRAB and SCAN domains 1

Gene

Zkscan1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri375 – 397C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 6PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein with KRAB and SCAN domains 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zkscan1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1921820, Zkscan1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000029729

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000477541 – 561Zinc finger protein with KRAB and SCAN domains 1Add BLAST561

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei13PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki27Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki180Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki226Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki277Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki296Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki301Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki336Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki373Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki410Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki438Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki476Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki558Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q8BGS3

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8BGS3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8BGS3

PeptideAtlas

More...PeptideAtlasi		Q8BGS3

PRoteomics IDEntifications database

More...PRIDEi		Q8BGS3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		275372 [Q8BGS3-1]
275373 [Q8BGS3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8BGS3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8BGS3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000029729, Expressed in skin of back and 266 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8BGS3, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		216852, 2 interactors

Protein interaction database and analysis system

More...IntActi		Q8BGS3, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000019660

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8BGS3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8BGS3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini56 – 138SCAN boxPROSITE-ProRule annotationAdd BLAST83
Domaini225 – 304KRABAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 51DisorderedSequence analysisAdd BLAST51
Regioni163 – 187DisorderedSequence analysisAdd BLAST25
Regioni260 – 372DisorderedSequence analysisAdd BLAST113

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 16Polar residuesSequence analysisAdd BLAST16
Compositional biasi166 – 180Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi274 – 349Basic and acidic residuesSequence analysisAdd BLAST76
Compositional biasi355 – 369Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri375 – 397C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 6PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161592

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_49_8_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8BGS3

Identification of Orthologs from Complete Genome Data

More...OMAi		HRIHNRE

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8BGS3

TreeFam database of animal gene trees

More...TreeFami		TF350830

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit
cd07936, SCAN, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.4020.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 6 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 6 hits
PS50157, ZINC_FINGER_C2H2_2, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q8BGS3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMTAESRETT GLSPQAAQEK DGIVIVKVEE EDEEDHMWGQ DSSLQETPPP 
        60         70         80         90        100
DPEVFRQRFR RFCYQNTFGP REALNRLKEL CHQWLRPEVN SKEQILELLV 
       110        120        130        140        150
LEQFLSILPK ELQVWLQEYR PDSGEEAVTL LEDLELDLSG QQVPGQVHGP 
       160        170        180        190        200
EMLARGVVPL DPVQESSSFD HHETAQSHFK HSSRKPRLLS RALPATHVPA 
       210        220        230        240        250
PHHEGNPRDQ AMASALLTAD SQAMVKIEDM AVSLILEEWG CQNLARRNLN 
       260        270        280        290        300
RDSRQMNLGN VFSQGSENRN GNESTSKAEV KEDSTSHGEI AGRFQKEFGE 
       310        320        330        340        350
KREQQGRVVE RQQKNPEEKT GKEKKEPGPP TAKEKKPSTG ERGPREKGKG 
       360        370        380        390        400
LGRSFSLSAN FNNTPEEAPS GAKTHRCDEC GKCFTRSSSL IRHKIIHTGE 
       410        420        430        440        450
KPYECNECGK AFSLNSNLVL HQRIHTGEKP HECNECGKAF SHSSNLILHQ 
       460        470        480        490        500
RIHSGEKPYE CNECGKAFSQ SSDLTKHQRI HTGEKPYECS ECGKAFNRNS 
       510        520        530        540        550
YLILHRRIHT REKPYKCTKC GKAFTRSSTL TLHHRIHARE RTSEYSPASL 
       560 
DAFGAFLKSC V
Length:561
Mass (Da):63,439
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i757C4FD2CFB28DDB
GO
Isoform 2 (identifier: Q8BGS3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     192-264: Missing.

Show »
Length:488
Mass (Da):55,419
Checksum:i27550A06A08F45B6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC27539 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti244L → M in BAC27539 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_016958192 – 264Missing in isoform 2. 2 PublicationsAdd BLAST73

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK131148 mRNA Translation: BAD21398.1
AK020039 mRNA Translation: BAB31975.1
AK028932 mRNA Translation: BAC26200.1
AK031759 mRNA Translation: BAC27539.1 Frameshift.
AK036807 mRNA Translation: BAC29584.1
AK054323 mRNA Translation: BAC35730.1
AK135999 mRNA Translation: BAE22767.1
BC052441 mRNA Translation: AAH52441.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS19788.1 [Q8BGS3-2]
CCDS19789.1 [Q8BGS3-1]

NCBI Reference Sequences

More...RefSeqi		NP_084145.1, NM_029869.1 [Q8BGS3-2]
NP_598667.2, NM_133906.4 [Q8BGS3-1]
XP_006504691.1, XM_006504628.3 [Q8BGS3-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000019660; ENSMUSP00000019660; ENSMUSG00000029729 [Q8BGS3-1]
ENSMUST00000066617; ENSMUSP00000068480; ENSMUSG00000029729 [Q8BGS3-2]
ENSMUST00000110962; ENSMUSP00000106587; ENSMUSG00000029729 [Q8BGS3-2]
ENSMUST00000110963; ENSMUSP00000106588; ENSMUSG00000029729 [Q8BGS3-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		74570

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:74570

UCSC genome browser

More...UCSCi		uc009aej.1, mouse [Q8BGS3-1]
uc009aek.1, mouse [Q8BGS3-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131148 mRNA Translation: BAD21398.1
AK020039 mRNA Translation: BAB31975.1
AK028932 mRNA Translation: BAC26200.1
AK031759 mRNA Translation: BAC27539.1 Frameshift.
AK036807 mRNA Translation: BAC29584.1
AK054323 mRNA Translation: BAC35730.1
AK135999 mRNA Translation: BAE22767.1
BC052441 mRNA Translation: AAH52441.1
CCDSiCCDS19788.1 [Q8BGS3-2]
CCDS19789.1 [Q8BGS3-1]
RefSeqiNP_084145.1, NM_029869.1 [Q8BGS3-2]
NP_598667.2, NM_133906.4 [Q8BGS3-1]
XP_006504691.1, XM_006504628.3 [Q8BGS3-2]

3D structure databases

SMRiQ8BGS3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi216852, 2 interactors
IntActiQ8BGS3, 1 interactor
STRINGi10090.ENSMUSP00000019660

PTM databases

iPTMnetiQ8BGS3
PhosphoSitePlusiQ8BGS3

Proteomic databases

EPDiQ8BGS3
MaxQBiQ8BGS3
PaxDbiQ8BGS3
PeptideAtlasiQ8BGS3
PRIDEiQ8BGS3
ProteomicsDBi275372 [Q8BGS3-1]
275373 [Q8BGS3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		1764, 166 antibodies from 22 providers

Genome annotation databases

EnsembliENSMUST00000019660; ENSMUSP00000019660; ENSMUSG00000029729 [Q8BGS3-1]
ENSMUST00000066617; ENSMUSP00000068480; ENSMUSG00000029729 [Q8BGS3-2]
ENSMUST00000110962; ENSMUSP00000106587; ENSMUSG00000029729 [Q8BGS3-2]
ENSMUST00000110963; ENSMUSP00000106588; ENSMUSG00000029729 [Q8BGS3-2]
GeneIDi74570
KEGGimmu:74570
UCSCiuc009aej.1, mouse [Q8BGS3-1]
uc009aek.1, mouse [Q8BGS3-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		7586
MGIiMGI:1921820, Zkscan1
VEuPathDBiHostDB:ENSMUSG00000029729

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000161592
HOGENOMiCLU_002678_49_8_1
InParanoidiQ8BGS3
OMAiHRIHNRE
OrthoDBi1318335at2759
PhylomeDBiQ8BGS3
TreeFamiTF350830

Enzyme and pathway databases

ReactomeiR-MMU-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		74570, 3 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Zkscan1, mouse

Protein Ontology

More...PROi		PR:Q8BGS3
RNActiQ8BGS3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000029729, Expressed in skin of back and 266 other tissues
GenevisibleiQ8BGS3, MM

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
cd07936, SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR003309, SCAN_dom
IPR038269, SCAN_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF02023, SCAN, 1 hit
PF00096, zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00431, SCAN, 1 hit
SM00355, ZnF_C2H2, 6 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS50804, SCAN_BOX, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 6 hits
PS50157, ZINC_FINGER_C2H2_2, 6 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZKSC1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BGS3
Secondary accession number(s): Q7TS88, Q8BJ55, Q9CRN6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: March 1, 2003
Last modified: February 23, 2022
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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