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Protein

RING finger protein 24

Gene

Rnf24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in TRPCs intracellular trafficking.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri78 – 119RING-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RING finger protein 24
Gene namesi
Name:Rnf24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1261771 Rnf24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 44HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000560641 – 148RING finger protein 24Add BLAST148

Proteomic databases

MaxQBiQ8BGI1
PaxDbiQ8BGI1
PRIDEiQ8BGI1

PTM databases

iPTMnetiQ8BGI1
PhosphoSitePlusiQ8BGI1
SwissPalmiQ8BGI1

Expressioni

Gene expression databases

BgeeiENSMUSG00000048911 Expressed in 228 organ(s), highest expression level in adult mammalian kidney
CleanExiMM_RNF24
ExpressionAtlasiQ8BGI1 baseline and differential
GenevisibleiQ8BGI1 MM

Interactioni

Subunit structurei

Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000058630

Structurei

3D structure databases

ProteinModelPortaliQ8BGI1
SMRiQ8BGI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri78 – 119RING-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Transmembrane, Transmembrane helix, Zinc-finger

Phylogenomic databases

eggNOGiKOG0800 Eukaryota
ENOG41121N2 LUCA
GeneTreeiENSGT00710000106755
HOGENOMiHOG000004806
HOVERGENiHBG058899
InParanoidiQ8BGI1
OMAiMSSDFQH
OrthoDBiEOG091G0PFG
PhylomeDBiQ8BGI1

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001841 Znf_RING
IPR011016 Znf_RING-CH
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF13639 zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
SM00744 RINGv, 1 hit
PROSITEiView protein in PROSITE
PS50089 ZF_RING_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8BGI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAVFVFILSL LFCCYLIRLR
60 70 80 90 100
HQAHKEFYAY KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF
110 120 130 140
HRKCLVKWLE VRKVCPLCNM PVLQLAQLHS KQDRGPPQEP LPGAENIV
Length:148
Mass (Da):17,254
Last modified:March 1, 2003 - v1
Checksum:i96DFD3E31B6CC5C8
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
V9GXF9V9GXF9_MOUSE
RING finger protein 24
Rnf24 mCG_18508
95Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK048813 mRNA Translation: BAC33467.1
AK083665 mRNA Translation: BAC38987.1
AK089207 mRNA Translation: BAC40793.1
CCDSiCCDS16762.1
RefSeqiNP_848722.1, NM_178607.4
UniGeneiMm.477523

Genome annotation databases

EnsembliENSMUST00000059372; ENSMUSP00000058630; ENSMUSG00000048911
ENSMUST00000110194; ENSMUSP00000105823; ENSMUSG00000048911
ENSMUST00000165420; ENSMUSP00000129843; ENSMUSG00000048911
GeneIDi51902
KEGGimmu:51902
UCSCiuc008mlk.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK048813 mRNA Translation: BAC33467.1
AK083665 mRNA Translation: BAC38987.1
AK089207 mRNA Translation: BAC40793.1
CCDSiCCDS16762.1
RefSeqiNP_848722.1, NM_178607.4
UniGeneiMm.477523

3D structure databases

ProteinModelPortaliQ8BGI1
SMRiQ8BGI1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000058630

PTM databases

iPTMnetiQ8BGI1
PhosphoSitePlusiQ8BGI1
SwissPalmiQ8BGI1

Proteomic databases

MaxQBiQ8BGI1
PaxDbiQ8BGI1
PRIDEiQ8BGI1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000059372; ENSMUSP00000058630; ENSMUSG00000048911
ENSMUST00000110194; ENSMUSP00000105823; ENSMUSG00000048911
ENSMUST00000165420; ENSMUSP00000129843; ENSMUSG00000048911
GeneIDi51902
KEGGimmu:51902
UCSCiuc008mlk.2 mouse

Organism-specific databases

CTDi11237
MGIiMGI:1261771 Rnf24

Phylogenomic databases

eggNOGiKOG0800 Eukaryota
ENOG41121N2 LUCA
GeneTreeiENSGT00710000106755
HOGENOMiHOG000004806
HOVERGENiHBG058899
InParanoidiQ8BGI1
OMAiMSSDFQH
OrthoDBiEOG091G0PFG
PhylomeDBiQ8BGI1

Miscellaneous databases

PROiPR:Q8BGI1
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000048911 Expressed in 228 organ(s), highest expression level in adult mammalian kidney
CleanExiMM_RNF24
ExpressionAtlasiQ8BGI1 baseline and differential
GenevisibleiQ8BGI1 MM

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001841 Znf_RING
IPR011016 Znf_RING-CH
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF13639 zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
SM00744 RINGv, 1 hit
PROSITEiView protein in PROSITE
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRNF24_MOUSE
AccessioniPrimary (citable) accession number: Q8BGI1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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