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Entry version 123 (02 Jun 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Doublesex- and mab-3-related transcription factor 2

Gene

Dmrt2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome. Is not required for sex determination and/or differentiation in embryonic development. Also not involved in symmetric somite formation and hence does not regulate the laterality pathway that controls left-right asymmetric organ positioning.

5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi123 – 170DMPROSITE-ProRule annotationAdd BLAST48

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Doublesex- and mab-3-related transcription factor 2By similarityImported
Alternative name(s):
Doublesex-like 2 proteinBy similarity
Terra1 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dmrt2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1330307, Dmrt2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice heterozygous for Dmrt2 mutation exhibit no visible phenotype. Homozygotes are perinatally lethal due to signs of respiratory distress. They have rib, sternal, vertebral and skull base malformations. Expression of myogenic growth factors, such as Pax3 and Myog, the growth factor Pdgfa, cadherin Cdh2, and the filament protein Des is abnormal. Mutants lack most or all of the epithelial organization seen in wild-type somites, sclerotome and dermomyotome. Mutants have disrupted production of matrix components including laminin-1 in the dermomyotome. Arrangement of the myogenic cells of the inter-limb somites is abnormal. Myf5 activation in the epaxial domain is retarded thus having consequences in the myogenesis by delaying expression of Myog. Mutants do not have left-right defects regarding internal organs positioning. Dmrt2 and Pax3 double null mutant embryos exhibit suspended development and Myog expression is markedly decreased and its expression pattern dramatically distorted.4 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004230101 – 561Doublesex- and mab-3-related transcription factor 2Add BLAST561

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8BG36

PRoteomics IDEntifications database

More...
PRIDEi
Q8BG36

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
279439

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8BG36

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in testis.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in presomitic mesoderm and developing somites at 8.5 dpc, accumulating in the epaxial domain at 9.5 dpc in the immature caudal somites. At 10.5 dpc expressed in the dermomyotome of somites. By 11.5 dpc, only detectable in caudal somites. In mature somites, expression is confined to the dermomyotome of the somite where Pax3 is also expressed and in the epaxial domain of the most immature caudal somites. At this stage, the most mature anterior somites are beginning to lose the expression at the epaxial and hypaxial extremities of the dermomyotome. At 14.5 dpc expressed in testis, heart and brain. Expression is also detected in proximal forelimb buds and branchial arches of the developing embryo.4 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Transcriptionally up-regulated by PAX3 within the dermomyotome.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000048138, Expressed in white adipose tissue and 121 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8BG36, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
230465, 25 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000059654

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8BG36, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8BG36

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 119DisorderedSequence analysisAdd BLAST119

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi43 – 68Acidic residuesSequence analysisAdd BLAST26
Compositional biasi81 – 95Pro residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DMRT family.Sequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3815, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156282

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_030932_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8BG36

Identification of Orthologs from Complete Genome Data

More...
OMAi
FVMWPRG

Database of Orthologous Groups

More...
OrthoDBi
897429at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8BG36

TreeFam database of animal gene trees

More...
TreeFami
TF317837

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1040.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001275, DM_DNA-bd
IPR036407, DM_DNA-bd_sf
IPR026607, DMRT/dsx/mab-3

The PANTHER Classification System

More...
PANTHERi
PTHR12322, PTHR12322, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00751, DM, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00301, DM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82927, SSF82927, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS40000, DM_1, 1 hit
PS50809, DM_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8BG36-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEGQAVPGV GDWEIDVESL DLEEDSCGTP LRATPPQEPS PAAADGEEDE
60 70 80 90 100
DEEEEDEDVE DEGDGEEPGV SSEVPGRPEQ PGGLAPRPPP AAQALPAAAA
110 120 130 140 150
APERGATAGG GAEPRKLSRT PKCARCRNHG VVSCLKGHKR FCRWRDCQCA
160 170 180 190 200
NCLLVVERQR VMAAQVALRR QQATEDKKGL SGKQNNFDRK AVYQRQVRAP
210 220 230 240 250
SLLAKSILEG YRPMTAETYL GGTLPLPPPV SDRMRKRRAF ADKELENIML
260 270 280 290 300
EREYKEREML ETSQAAALFL PNRMVPGPEY SSYKGTYSPT AGELPSKDFC
310 320 330 340 350
NFLPTCLDLT MQYSGSGNME LISSNVSVAT TYRQYPLSSR FLVWPKCGPI
360 370 380 390 400
SDTLLYQQYL LNATTSVQAL KPGTGWDLKG TRVQDGLSAE QDMMPPKLEG
410 420 430 440 450
SLVLPHLPEV PASRTDLQVH QVVPERSAFS PPGRNFSPIV DMDCLAAQGH
460 470 480 490 500
VLTKLSKENT RPSLPLKTNP FHSVFQQTLS DKSGPELNAP FVKEAFEETP
510 520 530 540 550
KKHRECLVKE SQKYTFTIDR CAKDLFVAKQ VGTKLSANEP LSFSVESILK
560
RPSSAVTHVS Q
Length:561
Mass (Da):61,641
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC4430D9F9EC4D68
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD38425 differs from that shown.Curated
The sequence AAH27669 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAE24347 differs from that shown. Reason: Frameshift.Curated
The sequence CAB93343 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti19S → I in BAE24344 (PubMed:16141072).Curated1
Sequence conflicti19S → I in BAE24347 (PubMed:16141072).Curated1
Sequence conflicti90P → A in CAB93343 (PubMed:10857744).Curated1
Sequence conflicti176D → V in CAB93343 (PubMed:10857744).Curated1
Sequence conflicti274M → K in AAD38425 (PubMed:10021344).Curated1
Sequence conflicti434R → Q in BAE24344 (PubMed:16141072).Curated1
Sequence conflicti434R → Q in BAE24347 (PubMed:16141072).Curated1
Sequence conflicti524D → E in BAE24344 (PubMed:16141072).Curated1
Sequence conflicti524D → E in BAE24347 (PubMed:16141072).Curated1
Sequence conflicti547S → L in BAE24347 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF539811 mRNA Translation: AAN77205.1
AK044891 mRNA Translation: BAC32130.1
AK140337 mRNA Translation: BAE24344.1
AK140347 mRNA Translation: BAE24347.1 Frameshift.
AC124540 Genomic DNA No translation available.
AC132140 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41636.1
AJ276456 Genomic DNA Translation: CAB93343.1 Frameshift.
AJ276459 Genomic DNA Translation: CAB93346.1
AF080623 mRNA Translation: AAD38425.1 Sequence problems.
BC027669 mRNA Translation: AAH27669.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS29719.1

NCBI Reference Sequences

More...
RefSeqi
NP_665830.1, NM_145831.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000053068; ENSMUSP00000059654; ENSMUSG00000048138

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
226049

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:226049

UCSC genome browser

More...
UCSCi
uc008hbm.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF539811 mRNA Translation: AAN77205.1
AK044891 mRNA Translation: BAC32130.1
AK140337 mRNA Translation: BAE24344.1
AK140347 mRNA Translation: BAE24347.1 Frameshift.
AC124540 Genomic DNA No translation available.
AC132140 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41636.1
AJ276456 Genomic DNA Translation: CAB93343.1 Frameshift.
AJ276459 Genomic DNA Translation: CAB93346.1
AF080623 mRNA Translation: AAD38425.1 Sequence problems.
BC027669 mRNA Translation: AAH27669.1 Different initiation.
CCDSiCCDS29719.1
RefSeqiNP_665830.1, NM_145831.3

3D structure databases

SMRiQ8BG36
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230465, 25 interactors
STRINGi10090.ENSMUSP00000059654

PTM databases

PhosphoSitePlusiQ8BG36

Proteomic databases

PaxDbiQ8BG36
PRIDEiQ8BG36
ProteomicsDBi279439

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
9092, 72 antibodies

The DNASU plasmid repository

More...
DNASUi
226049

Genome annotation databases

EnsembliENSMUST00000053068; ENSMUSP00000059654; ENSMUSG00000048138
GeneIDi226049
KEGGimmu:226049
UCSCiuc008hbm.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10655
MGIiMGI:1330307, Dmrt2

Phylogenomic databases

eggNOGiKOG3815, Eukaryota
GeneTreeiENSGT00940000156282
HOGENOMiCLU_030932_0_0_1
InParanoidiQ8BG36
OMAiFVMWPRG
OrthoDBi897429at2759
PhylomeDBiQ8BG36
TreeFamiTF317837

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
226049, 5 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Dmrt2, mouse

Protein Ontology

More...
PROi
PR:Q8BG36
RNActiQ8BG36, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000048138, Expressed in white adipose tissue and 121 other tissues
GenevisibleiQ8BG36, MM

Family and domain databases

Gene3Di4.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR001275, DM_DNA-bd
IPR036407, DM_DNA-bd_sf
IPR026607, DMRT/dsx/mab-3
PANTHERiPTHR12322, PTHR12322, 1 hit
PfamiView protein in Pfam
PF00751, DM, 1 hit
SMARTiView protein in SMART
SM00301, DM, 1 hit
SUPFAMiSSF82927, SSF82927, 1 hit
PROSITEiView protein in PROSITE
PS40000, DM_1, 1 hit
PS50809, DM_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDMRT2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BG36
Secondary accession number(s): Q3USI4
, Q3USI7, Q8K185, Q9JJU0, Q9JJU3, Q9WVM0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2013
Last sequence update: March 1, 2003
Last modified: June 2, 2021
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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