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Entry version 121 (16 Oct 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Sodium-dependent neutral amino acid transporter B(0)AT2

Gene

Slc6a15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for methionine and for the branched-chain amino acids, particularly leucine, valine and isoleucine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity).By similarity1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=195 µM for proline (in the presence of 100 mM NaCL)1 Publication
  2. KM=510 µM for proline (in the presence of 30 mM NaCL)1 Publication
  3. KM=790 µM for proline (in the presence of 3 mM NaCL)1 Publication
  4. KM=81 µM for leucine1 Publication
  5. KM=58 µM for isoleucine1 Publication
  6. KM=40 µM for methionine1 Publication
  7. KM=670 µM for alanine1 Publication

    pH dependencei

    Optimum pH is 7.5-8.5.1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processAmino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport
    LigandSodium

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-MMU-352230 Amino acid transport across the plasma membrane
    R-MMU-442660 Na+/Cl- dependent neurotransmitter transporters

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Sodium-dependent neutral amino acid transporter B(0)AT2
    Alternative name(s):
    Sodium- and chloride-dependent neurotransmitter transporter NTT73
    Solute carrier family 6 member 15
    Transporter v7-3
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:Slc6a15
    Synonyms:B0at2, Ntt73
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

    Organism-specific databases

    Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

    More...
    MGIi
    MGI:2143484 Slc6a15

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 69CytoplasmicSequence analysisAdd BLAST69
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei70 – 90Helical; Name=1Sequence analysisAdd BLAST21
    Transmembranei98 – 117Helical; Name=2Sequence analysisAdd BLAST20
    Transmembranei142 – 162Helical; Name=3Sequence analysisAdd BLAST21
    Topological domaini163 – 225ExtracellularSequence analysisAdd BLAST63
    Transmembranei226 – 244Helical; Name=4Sequence analysisAdd BLAST19
    Transmembranei253 – 270Helical; Name=5Sequence analysisAdd BLAST18
    Transmembranei306 – 323Helical; Name=6Sequence analysisAdd BLAST18
    Transmembranei335 – 356Helical; Name=7Sequence analysisAdd BLAST22
    Topological domaini357 – 452ExtracellularSequence analysisAdd BLAST96
    Transmembranei453 – 472Helical; Name=8Sequence analysisAdd BLAST20
    Transmembranei496 – 514Helical; Name=9Sequence analysisAdd BLAST19
    Transmembranei530 – 550Helical; Name=10Sequence analysisAdd BLAST21
    Transmembranei571 – 592Helical; Name=11Sequence analysisAdd BLAST22
    Transmembranei620 – 642Helical; Name=12Sequence analysisAdd BLAST23
    Topological domaini643 – 729CytoplasmicSequence analysisAdd BLAST87

    Keywords - Cellular componenti

    Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Mice are viable and fertile and fail to demonstrate any striking abnormality in motor and sensory functions. Other transporters could help to compensate for lost of SLC6A15.1 Publication

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002147991 – 729Sodium-dependent neutral amino acid transporter B(0)AT2Add BLAST729

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei25PhosphoserineBy similarity1
    Modified residuei55PhosphoserineBy similarity1
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi187N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi276N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi383N-linked (GlcNAc...) asparagineSequence analysis1
    Glycosylationi394N-linked (GlcNAc...) asparagineSequence analysis1
    Modified residuei687PhosphoserineBy similarity1
    Modified residuei699PhosphoserineBy similarity1
    Modified residuei701PhosphoserineBy similarity1

    Keywords - PTMi

    Glycoprotein, Phosphoprotein

    Proteomic databases

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    Q8BG16

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q8BG16

    PeptideAtlas

    More...
    PeptideAtlasi
    Q8BG16

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q8BG16

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q8BG16

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q8BG16

    SwissPalm database of S-palmitoylation events

    More...
    SwissPalmi
    Q8BG16

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Significant expressed in brain, lung and kidney. regions, the cortex, the cerebellum and the brain stem.1 Publication

    <p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

    Detected throughout development, starting with the pre-implantation embryo.1 Publication

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSMUSG00000019894 Expressed in 209 organ(s), highest expression level in saccule of membranous labyrinth

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q8BG16 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q8BG16 MM

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    10090.ENSMUSP00000073829

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG3659 Eukaryota
    COG0733 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00940000157277

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000116406

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q8BG16

    KEGG Orthology (KO)

    More...
    KOi
    K05048

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    MIPHHIN

    Database of Orthologous Groups

    More...
    OrthoDBi
    250396at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q8BG16

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF352709

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR000175 Na/ntran_symport
    IPR002438 Neutral_aa_SLC6
    IPR037272 SNS_sf

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR11616 PTHR11616, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00209 SNF, 1 hit

    Protein Motif fingerprint database; a protein domain database

    More...
    PRINTSi
    PR00176 NANEUSMPORT
    PR01206 ORPHTRNSPORT

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF161070 SSF161070, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00610 NA_NEUROTRAN_SYMP_1, 1 hit
    PS00754 NA_NEUROTRAN_SYMP_2, 1 hit
    PS50267 NA_NEUROTRAN_SYMP_3, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

    Q8BG16-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MPKNSKVVKR DLDDDVIESV KDLLSNEDSV EEVSKKSELI VDVQEEKDTD
    60 70 80 90 100
    AEDGSEADDE RPAWNSKLQY ILAQVGFSVG LGNVWRFPYL CQKNGGGAYL
    110 120 130 140 150
    LPYLILLLVI GIPLFFLELS VGQRIRRGSI GVWNYISPKL GGIGFASCVV
    160 170 180 190 200
    CYFVALYYNV IIGWTLFYFS QSFQQPLPWD QCPLVKNASH TYVEPECEQS
    210 220 230 240 250
    SATTYYWYRE ALDITSSISD SGGLNWKMTV CLLVAWVMVC LAMIKGIQSS
    260 270 280 290 300
    GKIMYFSSLF PYVVLICFLI RSLLLNGSID GIRHMFTPKL EMMLEPKVWR
    310 320 330 340 350
    EAATQVFFAL GLGFGGVIAF SSYNKRDNNC HFDAVLVSFI NFFTSVLATL
    360 370 380 390 400
    VVFAVLGFKA NIVNEKCISQ NSEMILKLLK MGNISWDVIP HHINLSAVTV
    410 420 430 440 450
    EDYRLVYDII QKVKEEEFAV LHLNACQIED ELNKAVQGTG LAFIAFTEAM
    460 470 480 490 500
    THFPASPFWS VMFFLMLINL GLGSMFGTIE GIITPIVDTF KVRKEILTVI
    510 520 530 540 550
    CCLLAFCIGL IFVQRSGNYF VTMFDDYSAT LPLLIVVILE NIAVSFVYGI
    560 570 580 590 600
    DKFIEDLTDM LGFAPSKYYY YMWKYISPLM LLTLLIASIV NMGLSPPGYN
    610 620 630 640 650
    AWIKEKASEE FLSYPMWGMV VCFSLMVLAI LPVPVVFIIR RCNLIDDSSG
    660 670 680 690 700
    NLASVTYKRG RVLKEPVNLE GDDASLIHGK IPSEMSSPNF GKNIYRKQSG
    710 720
    SPTLDTAPNG RYGIGYLMAD MPDMPESDL
    Length:729
    Mass (Da):81,792
    Last modified:March 1, 2003 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD336735E9D1E9B97
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    A0A1W2P744A0A1W2P744_MOUSE
    Transporter
    Slc6a15
    127Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AY149280 mRNA Translation: AAN75437.1
    AY149281 mRNA Translation: AAN75438.1
    AY149282 Genomic DNA Translation: AAN75439.1
    AM085111 mRNA Translation: CAJ29896.1
    AK036136 mRNA Translation: BAC29315.1
    CH466539 Genomic DNA Translation: EDL21676.1
    CH466539 Genomic DNA Translation: EDL21677.1
    BC076593 mRNA Translation: AAH76593.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS24156.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001239259.1, NM_001252330.1
    NP_780537.1, NM_175328.3
    XP_006513045.1, XM_006512982.3
    XP_006513046.1, XM_006512983.3
    XP_006513047.1, XM_006512984.3

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENSMUST00000074204; ENSMUSP00000073829; ENSMUSG00000019894
    ENSMUST00000179636; ENSMUSP00000136676; ENSMUSG00000019894

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    103098

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    mmu:103098

    UCSC genome browser

    More...
    UCSCi
    uc007gyj.2 mouse

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AY149280 mRNA Translation: AAN75437.1
    AY149281 mRNA Translation: AAN75438.1
    AY149282 Genomic DNA Translation: AAN75439.1
    AM085111 mRNA Translation: CAJ29896.1
    AK036136 mRNA Translation: BAC29315.1
    CH466539 Genomic DNA Translation: EDL21676.1
    CH466539 Genomic DNA Translation: EDL21677.1
    BC076593 mRNA Translation: AAH76593.1
    CCDSiCCDS24156.1
    RefSeqiNP_001239259.1, NM_001252330.1
    NP_780537.1, NM_175328.3
    XP_006513045.1, XM_006512982.3
    XP_006513046.1, XM_006512983.3
    XP_006513047.1, XM_006512984.3

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000073829

    PTM databases

    iPTMnetiQ8BG16
    PhosphoSitePlusiQ8BG16
    SwissPalmiQ8BG16

    Proteomic databases

    MaxQBiQ8BG16
    PaxDbiQ8BG16
    PeptideAtlasiQ8BG16
    PRIDEiQ8BG16

    Genome annotation databases

    EnsembliENSMUST00000074204; ENSMUSP00000073829; ENSMUSG00000019894
    ENSMUST00000179636; ENSMUSP00000136676; ENSMUSG00000019894
    GeneIDi103098
    KEGGimmu:103098
    UCSCiuc007gyj.2 mouse

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    55117
    MGIiMGI:2143484 Slc6a15

    Phylogenomic databases

    eggNOGiKOG3659 Eukaryota
    COG0733 LUCA
    GeneTreeiENSGT00940000157277
    HOGENOMiHOG000116406
    InParanoidiQ8BG16
    KOiK05048
    OMAiMIPHHIN
    OrthoDBi250396at2759
    PhylomeDBiQ8BG16
    TreeFamiTF352709

    Enzyme and pathway databases

    ReactomeiR-MMU-352230 Amino acid transport across the plasma membrane
    R-MMU-442660 Na+/Cl- dependent neurotransmitter transporters

    Miscellaneous databases

    Protein Ontology

    More...
    PROi
    PR:Q8BG16

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSMUSG00000019894 Expressed in 209 organ(s), highest expression level in saccule of membranous labyrinth
    ExpressionAtlasiQ8BG16 baseline and differential
    GenevisibleiQ8BG16 MM

    Family and domain databases

    InterProiView protein in InterPro
    IPR000175 Na/ntran_symport
    IPR002438 Neutral_aa_SLC6
    IPR037272 SNS_sf
    PANTHERiPTHR11616 PTHR11616, 1 hit
    PfamiView protein in Pfam
    PF00209 SNF, 1 hit
    PRINTSiPR00176 NANEUSMPORT
    PR01206 ORPHTRNSPORT
    SUPFAMiSSF161070 SSF161070, 1 hit
    PROSITEiView protein in PROSITE
    PS00610 NA_NEUROTRAN_SYMP_1, 1 hit
    PS00754 NA_NEUROTRAN_SYMP_2, 1 hit
    PS50267 NA_NEUROTRAN_SYMP_3, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

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    ProtoNeti
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    MobiDB: a database of protein disorder and mobility annotations

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    MobiDBi
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    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS6A15_MOUSE
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BG16
    Secondary accession number(s): Q333Y0
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
    Last sequence update: March 1, 2003
    Last modified: October 16, 2019
    This is version 121 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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