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Protein
Submitted name:

Ectonucleoside triphosphate diphosphohydrolase 3

Gene

Entpd3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BRENDAi3.6.1.5 3474
ReactomeiR-MMU-8850843 Phosphate bond hydrolysis by NTPDase proteins

Names & Taxonomyi

Protein namesi
Submitted name:
Ectonucleoside triphosphate diphosphohydrolase 3Imported
Submitted name:
Nucleoside triphosphate diphosphohydrolase-3Imported (EC:3.6.1.5Imported)
Gene namesi
Name:Entpd3Imported
ORF Names:mCG_22707Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1321386 Entpd3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Transmembranei486 – 508HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000041608 Expressed in 184 organ(s), highest expression level in dorsal pancreas

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036830

Family & Domainsi

Sequence similaritiesi

Belongs to the GDA1/CD39 NTPase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1386 Eukaryota
COG5371 LUCA
GeneTreeiENSGT00550000074435
HOGENOMiHOG000059572
HOVERGENiHBG018982
KOiK01510
OMAiAFEDCMQ
OrthoDBiEOG091G05FZ
TreeFamiTF332859

Family and domain databases

InterProiView protein in InterPro
IPR000407 GDA1_CD39_NTPase
PANTHERiPTHR11782 PTHR11782, 1 hit
PfamiView protein in Pfam
PF01150 GDA1_CD39, 1 hit
PROSITEiView protein in PROSITE
PS01238 GDA1_CD39_NTPASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q8BFW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFTVMTRQPC EQAGFRALSR TPAIVTLVVL LVSIVVLVTL TLIQIRHPQV
60 70 80 90 100
LPPGLKYGVV LDAGSSRTTV YVYQWPAEKE NNTGVVSQTF RCSVKGSGIS
110 120 130 140 150
SYENNPQDAP KAFEDCILKV KEQVPEHLHG STRIYLGATA GMRLLRLQNE
160 170 180 190 200
TAAREVLESI QSYFKSQPFD FRGAQIISGQ EEGVYGWITA NYIMGNFLEK
210 220 230 240 250
NLWHMWVHPH GVDTTGALDL GGASTQISFV AGEKMEPNAS DTVQVSLYGY
260 270 280 290 300
TYTLYTHSFQ CYGQNEAEKK FLAMLLQSPS TEANISNPCY PQGYSTAFTL
310 320 330 340 350
GHVFGSLCTE KQRPESYNSS KSVTFMGTGD PRLCREKVAS VFDFNACQEQ
360 370 380 390 400
DACSFDGIYQ PKVQGPFVAF AGFYYTASAL NLSGSFSLTS FNDSSWDFCR
410 420 430 440 450
HTWSELPALL SRFDETYARS YCFSAHYIYH LLVNGYKFTE ETWPQIRFEK
460 470 480 490 500
EVGNSSIAWS LGYMLSLTNQ IPAGSPLIHL PIQPPVFMGV LAFFTAIALL
510 520
CLAFLLYLCS SFRTKERSEN AFDQAVDSD
Length:529
Mass (Da):58,984
Last modified:March 1, 2003 - v1
Checksum:iE34F5EF187484F2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123708 Genomic DNA No translation available.
AC137127 Genomic DNA No translation available.
BC079871 mRNA Translation: AAH79871.1
AY376710 mRNA Translation: AAQ86585.1
AY714060 mRNA Translation: AAU13839.1
AK046218 mRNA Translation: BAC32641.1
AK087561 mRNA Translation: BAC39928.1
CH466587 Genomic DNA Translation: EDL09171.1
RefSeqiNP_848791.2, NM_178676.4
UniGeneiMm.76648

Genome annotation databases

EnsembliENSMUST00000047687; ENSMUSP00000036830; ENSMUSG00000041608
GeneIDi215446
KEGGimmu:215446
UCSCiuc009scq.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123708 Genomic DNA No translation available.
AC137127 Genomic DNA No translation available.
BC079871 mRNA Translation: AAH79871.1
AY376710 mRNA Translation: AAQ86585.1
AY714060 mRNA Translation: AAU13839.1
AK046218 mRNA Translation: BAC32641.1
AK087561 mRNA Translation: BAC39928.1
CH466587 Genomic DNA Translation: EDL09171.1
RefSeqiNP_848791.2, NM_178676.4
UniGeneiMm.76648

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000036830

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000047687; ENSMUSP00000036830; ENSMUSG00000041608
GeneIDi215446
KEGGimmu:215446
UCSCiuc009scq.2 mouse

Organism-specific databases

CTDi956
MGIiMGI:1321386 Entpd3

Phylogenomic databases

eggNOGiKOG1386 Eukaryota
COG5371 LUCA
GeneTreeiENSGT00550000074435
HOGENOMiHOG000059572
HOVERGENiHBG018982
KOiK01510
OMAiAFEDCMQ
OrthoDBiEOG091G05FZ
TreeFamiTF332859

Enzyme and pathway databases

BRENDAi3.6.1.5 3474
ReactomeiR-MMU-8850843 Phosphate bond hydrolysis by NTPDase proteins

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041608 Expressed in 184 organ(s), highest expression level in dorsal pancreas

Family and domain databases

InterProiView protein in InterPro
IPR000407 GDA1_CD39_NTPase
PANTHERiPTHR11782 PTHR11782, 1 hit
PfamiView protein in Pfam
PF01150 GDA1_CD39, 1 hit
PROSITEiView protein in PROSITE
PS01238 GDA1_CD39_NTPASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8BFW6_MOUSE
AccessioniPrimary (citable) accession number: Q8BFW6
Secondary accession number(s): E9PYV0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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