Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 154 (02 Dec 2020)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
Add a publicationFeedback
Protein

Prosaposin

Gene

Psap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.UniRule annotation
Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ProsaposinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PsapImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97783, Psap

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

SecretedARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 16UniRule annotationAdd BLAST16
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501509903117 – 554ProsaposinUniRule annotationAdd BLAST538

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi63 ↔ 138UniRule annotation
Disulfide bondi66 ↔ 132UniRule annotation
Disulfide bondi94 ↔ 106UniRule annotation
Disulfide bondi197 ↔ 270UniRule annotation
Disulfide bondi200 ↔ 264UniRule annotation
Disulfide bondi229 ↔ 240UniRule annotation
Disulfide bondi314 ↔ 387UniRule annotation
Disulfide bondi317 ↔ 381UniRule annotation
Disulfide bondi345 ↔ 356UniRule annotation
Disulfide bondi439 ↔ 512UniRule annotation
Disulfide bondi442 ↔ 506UniRule annotation
Disulfide bondi470 ↔ 481UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotationARBA annotation, GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000004207, Expressed in stroma of bone marrow and 370 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 58Saposin A-typeInterPro annotationAdd BLAST41
Domaini59 – 142Saposin B-typeInterPro annotationAdd BLAST84
Domaini193 – 274Saposin B-typeInterPro annotationAdd BLAST82
Domaini310 – 391Saposin B-typeInterPro annotationAdd BLAST82
Domaini435 – 516Saposin B-typeInterPro annotationAdd BLAST82
Domaini518 – 554Saposin A-typeInterPro annotationAdd BLAST37

Keywords - Domaini

RepeatARBA annotation, SignalUniRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156695

Identification of Orthologs from Complete Genome Data

More...
OMAi
NIENQCD

TreeFam database of animal gene trees

More...
TreeFami
TF316942

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003119, SAP_A
IPR007856, SapB_1
IPR008138, SapB_2
IPR008373, Saposin
IPR011001, Saposin-like
IPR021165, Saposin_chordata
IPR008139, SaposinB_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02199, SapA, 2 hits
PF05184, SapB_1, 3 hits
PF03489, SapB_2, 4 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002431, Saposin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01797, SAPOSIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00162, SAPA, 2 hits
SM00741, SapB, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47862, SSF47862, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51110, SAP_A, 2 hits
PS50015, SAP_B, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8BFQ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYALALFASL LATALTSPVQ DPKTCSGGSA VLCRDVKTAV DCGAVKHCQQ
60 70 80 90 100
MVWSKPTAKS LPCDICKTVV TEAGNLLKDN ATQEEILHYL EKTCEWIHDS
110 120 130 140 150
SLSASCKEVV DSYLPVILDM IKGEMSNPGE VCSALNLCQS LQEYLAEQNQ
160 170 180 190 200
KQLESNKIPE VDMARVVAPF MSNIPLLLYP QDHPRSQPQP KANEDVCQDC
210 220 230 240 250
MKLVSDVQTA VKTNSSFIQG FVDHVKEDCD RLGPGVSDIC KNYVDQYSEV
260 270 280 290 300
CVQMLMHMQP KEICVLAGFC NEVKRVPMKT LVPATETIKN ILPALEMMDP
310 320 330 340 350
YEQNLVQAHN VILCQTCQFV MNKFSELIVN NATEELLVKG LSNACALLPD
360 370 380 390 400
PARTKCQEVV GTFGPSLLDI FIHEVNPSSL CGVIGLCAAR PELVEALEQP
410 420 430 440 450
APAIVSALLK EPTPPKQPAQ PKQSALPAHV PPQKNGGFCE VCKKLVLYLE
460 470 480 490 500
HNLEKNSTKE EILAALEKGC SFLPDPYQKQ CDDFVAEYEP LLLEILVEVM
510 520 530 540 550
DPGFVCSKIG VCPSAYKLLL GTEKCVWGPS YWCQNMETAA RCNAVDHCKR

HVWN
Length:554
Mass (Da):61,051
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF58DB79C7CC0C18
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q61207SAP_MOUSE
Prosaposin
Psap Sgp1
557Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QPG5J3QPG5_MOUSE
Prosaposin
Psap
557Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K3W4L3K3W4L3_MOUSE
Prosaposin
Psap
556Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PZ00E9PZ00_MOUSE
Prosaposin
Psap
551Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC079082 Genomic DNA No translation available.
BC145359 mRNA Translation: AAI45360.1
AK088369 mRNA Translation: BAC40308.1
AK089998 mRNA Translation: BAC41035.1
AK135637 mRNA Translation: BAE22597.1
AK145802 mRNA Translation: BAE26658.1
AK148152 mRNA Translation: BAE28378.1
AK150331 mRNA Translation: BAE29473.1
AK151034 mRNA Translation: BAE30051.1
AK151173 mRNA Translation: BAE30176.1
AK151230 mRNA Translation: BAE30222.1
AK151525 mRNA Translation: BAE30473.1
AK151686 mRNA Translation: BAE30610.1
AK151852 mRNA Translation: BAE30742.1
AK151891 mRNA Translation: BAE30775.1
AK151907 mRNA Translation: BAE30788.1
AK151943 mRNA Translation: BAE30819.1
AK152117 mRNA Translation: BAE30961.1
AK152126 mRNA Translation: BAE30967.1
AK152134 mRNA Translation: BAE30975.1
AK152203 mRNA Translation: BAE31032.1
AK152355 mRNA Translation: BAE31147.1
AK152505 mRNA Translation: BAE31272.1
AK152557 mRNA Translation: BAE31311.1
AK152605 mRNA Translation: BAE31352.1
AK152819 mRNA Translation: BAE31522.1
AK159108 mRNA Translation: BAE34824.1
AK159198 mRNA Translation: BAE34893.1
AK159266 mRNA Translation: BAE34946.1
AK159333 mRNA Translation: BAE34998.1
AK159341 mRNA Translation: BAE35003.1
AK159384 mRNA Translation: BAE35039.1
AK159427 mRNA Translation: BAE35074.1
AK159451 mRNA Translation: BAE35094.1
AK159457 mRNA Translation: BAE35099.1
AK159463 mRNA Translation: BAE35104.1
AK159487 mRNA Translation: BAE35122.1
AK159510 mRNA Translation: BAE35142.1
AK159528 mRNA Translation: BAE35157.1
AK159530 mRNA Translation: BAE35159.1
AK159589 mRNA Translation: BAE35209.1
AK159604 mRNA Translation: BAE35223.1
AK159657 mRNA Translation: BAE35266.1
AK159685 mRNA Translation: BAE35288.1
AK159720 mRNA Translation: BAE35315.1
AK159728 mRNA Translation: BAE35322.1
AK159840 mRNA Translation: BAE35418.1
AK159861 mRNA Translation: BAE35435.1
AK159862 mRNA Translation: BAE35436.1
AK159877 mRNA Translation: BAE35449.1
AK159910 mRNA Translation: BAE35473.1
AK159915 mRNA Translation: BAE35478.1
AK159936 mRNA Translation: BAE35496.1
AK159982 mRNA Translation: BAE35533.1
AK159994 mRNA Translation: BAE35544.1
AK160015 mRNA Translation: BAE35561.1
AK160024 mRNA Translation: BAE35567.1
AK160046 mRNA Translation: BAE35588.1
AK160877 mRNA Translation: BAE36065.1
AK161313 mRNA Translation: BAE36317.1
AK166700 mRNA Translation: BAE38955.1
AK166707 mRNA Translation: BAE38961.1
AK166744 mRNA Translation: BAE38986.1
AK166811 mRNA Translation: BAE39038.1
AK166849 mRNA Translation: BAE39068.1
AK166879 mRNA Translation: BAE39090.1
AK166909 mRNA Translation: BAE39110.1
AK166920 mRNA Translation: BAE39117.1
AK167014 mRNA Translation: BAE39190.1
AK167025 mRNA Translation: BAE39198.1
AK167111 mRNA Translation: BAE39259.1
AK167237 mRNA Translation: BAE39359.1
AK167418 mRNA Translation: BAE39506.1
AK170416 mRNA Translation: BAE41782.1

NCBI Reference Sequences

More...
RefSeqi
NP_001139592.1, NM_001146120.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000105465; ENSMUSP00000101105; ENSMUSG00000004207

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
19156

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079082 Genomic DNA No translation available.
BC145359 mRNA Translation: AAI45360.1
AK088369 mRNA Translation: BAC40308.1
AK089998 mRNA Translation: BAC41035.1
AK135637 mRNA Translation: BAE22597.1
AK145802 mRNA Translation: BAE26658.1
AK148152 mRNA Translation: BAE28378.1
AK150331 mRNA Translation: BAE29473.1
AK151034 mRNA Translation: BAE30051.1
AK151173 mRNA Translation: BAE30176.1
AK151230 mRNA Translation: BAE30222.1
AK151525 mRNA Translation: BAE30473.1
AK151686 mRNA Translation: BAE30610.1
AK151852 mRNA Translation: BAE30742.1
AK151891 mRNA Translation: BAE30775.1
AK151907 mRNA Translation: BAE30788.1
AK151943 mRNA Translation: BAE30819.1
AK152117 mRNA Translation: BAE30961.1
AK152126 mRNA Translation: BAE30967.1
AK152134 mRNA Translation: BAE30975.1
AK152203 mRNA Translation: BAE31032.1
AK152355 mRNA Translation: BAE31147.1
AK152505 mRNA Translation: BAE31272.1
AK152557 mRNA Translation: BAE31311.1
AK152605 mRNA Translation: BAE31352.1
AK152819 mRNA Translation: BAE31522.1
AK159108 mRNA Translation: BAE34824.1
AK159198 mRNA Translation: BAE34893.1
AK159266 mRNA Translation: BAE34946.1
AK159333 mRNA Translation: BAE34998.1
AK159341 mRNA Translation: BAE35003.1
AK159384 mRNA Translation: BAE35039.1
AK159427 mRNA Translation: BAE35074.1
AK159451 mRNA Translation: BAE35094.1
AK159457 mRNA Translation: BAE35099.1
AK159463 mRNA Translation: BAE35104.1
AK159487 mRNA Translation: BAE35122.1
AK159510 mRNA Translation: BAE35142.1
AK159528 mRNA Translation: BAE35157.1
AK159530 mRNA Translation: BAE35159.1
AK159589 mRNA Translation: BAE35209.1
AK159604 mRNA Translation: BAE35223.1
AK159657 mRNA Translation: BAE35266.1
AK159685 mRNA Translation: BAE35288.1
AK159720 mRNA Translation: BAE35315.1
AK159728 mRNA Translation: BAE35322.1
AK159840 mRNA Translation: BAE35418.1
AK159861 mRNA Translation: BAE35435.1
AK159862 mRNA Translation: BAE35436.1
AK159877 mRNA Translation: BAE35449.1
AK159910 mRNA Translation: BAE35473.1
AK159915 mRNA Translation: BAE35478.1
AK159936 mRNA Translation: BAE35496.1
AK159982 mRNA Translation: BAE35533.1
AK159994 mRNA Translation: BAE35544.1
AK160015 mRNA Translation: BAE35561.1
AK160024 mRNA Translation: BAE35567.1
AK160046 mRNA Translation: BAE35588.1
AK160877 mRNA Translation: BAE36065.1
AK161313 mRNA Translation: BAE36317.1
AK166700 mRNA Translation: BAE38955.1
AK166707 mRNA Translation: BAE38961.1
AK166744 mRNA Translation: BAE38986.1
AK166811 mRNA Translation: BAE39038.1
AK166849 mRNA Translation: BAE39068.1
AK166879 mRNA Translation: BAE39090.1
AK166909 mRNA Translation: BAE39110.1
AK166920 mRNA Translation: BAE39117.1
AK167014 mRNA Translation: BAE39190.1
AK167025 mRNA Translation: BAE39198.1
AK167111 mRNA Translation: BAE39259.1
AK167237 mRNA Translation: BAE39359.1
AK167418 mRNA Translation: BAE39506.1
AK170416 mRNA Translation: BAE41782.1
RefSeqiNP_001139592.1, NM_001146120.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1388, 437 antibodies

Genome annotation databases

EnsembliENSMUST00000105465; ENSMUSP00000101105; ENSMUSG00000004207
GeneIDi19156

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5660
MGIiMGI:97783, Psap

Phylogenomic databases

GeneTreeiENSGT00940000156695
OMAiNIENQCD
TreeFamiTF316942

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
19156, 0 hits in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Psap, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000004207, Expressed in stroma of bone marrow and 370 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR003119, SAP_A
IPR007856, SapB_1
IPR008138, SapB_2
IPR008373, Saposin
IPR011001, Saposin-like
IPR021165, Saposin_chordata
IPR008139, SaposinB_dom
PfamiView protein in Pfam
PF02199, SapA, 2 hits
PF05184, SapB_1, 3 hits
PF03489, SapB_2, 4 hits
PIRSFiPIRSF002431, Saposin, 1 hit
PRINTSiPR01797, SAPOSIN
SMARTiView protein in SMART
SM00162, SAPA, 2 hits
SM00741, SapB, 4 hits
SUPFAMiSSF47862, SSF47862, 3 hits
PROSITEiView protein in PROSITE
PS51110, SAP_A, 2 hits
PS50015, SAP_B, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8BFQ1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8BFQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: December 2, 2020
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again