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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 29NADUniRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBTHE:G13PU-5738-MONOMER
UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:BT_0825
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000001414 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001707401 – 479Altronate oxidoreductaseAdd BLAST479

Proteomic databases

PaxDbiQ8A9J0
PRIDEiQ8A9J0

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_0825

Structurei

3D structure databases

ProteinModelPortaliQ8A9J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DEI Bacteria
COG0246 LUCA
InParanoidiQ8A9J0
KOiK00041
OMAiVVIVRPI
OrthoDBiPOG091H0H06

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00670 Altron_oxidoreduct, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR023668 Altronate_OxRdtase
IPR013118 Mannitol_DH_C
IPR013131 Mannitol_DH_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01232 Mannitol_dh, 1 hit
PF08125 Mannitol_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

Q8A9J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKALNKETAP KVQRPERIIQ FGEGNFLRAF VDWIIYNMNQ KTDFNSSVVV
60 70 80 90 100
VQPIDKGMVD MLNAQDDLYH VNLQGLDKGE VVNSLTMIDV ISRALNPYTQ
110 120 130 140 150
NDEFMKLAEQ PEMRFVISNT TEAGIAFDPT CKLEDAPASS YPGKLTQLLY
160 170 180 190 200
HRFKTFNGDK TKGLIIFPCE LIFLNGHKLK ETIYQYIDLW NLGNEFKTWF
210 220 230 240 250
EEACGVYATL VDRIVPGFPR KDIAAIKEKI QYDDNLVVQA EIFHLWVIEA
260 270 280 290 300
PQEVAKEFPA DKAGLNVLFV PSEAPYHERK VTLLNGPHTV LSPVAYLSGV
310 320 330 340 350
NIVRDACQHE VIGKYIHKVM FDELMETLNL PKEELKKFAE DVLERFNNPF
360 370 380 390 400
VDHAVTSIML NSFPKYETRD LPGLKTYLER KGELPKGLVL GLAAIITYYK
410 420 430 440 450
GGVRADGAEI VPNDAPEIMN LLKELWATGC TKKVTEGVLA AEFIWGEDLN
460 470
KIPGLAAAVK ADLDSIQEKG MLETVKGIL
Length:479
Mass (Da):53,962
Last modified:June 1, 2003 - v1
Checksum:i29F5AFD94429B071
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA Translation: AAO75932.1
RefSeqiNP_809738.1, NC_004663.1
WP_008761512.1, NC_004663.1

Genome annotation databases

EnsemblBacteriaiAAO75932; AAO75932; BT_0825
GeneIDi1074221
31616927
KEGGibth:BT_0825
PATRICifig|226186.12.peg.842

Similar proteinsi

Entry informationi

Entry nameiUXAB_BACTN
AccessioniPrimary (citable) accession number: Q8A9J0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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