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UniProtKB - Q89AU1 (NUOG_BUCBP)

Entry version 111 (07 Apr 2021)
Sequence version 1 (01 Jun 2003)
Previous versions | rss
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Protein

NADH-quinone oxidoreductase subunit G

Gene

nuoG

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi34Iron-sulfur 1 (2Fe-2S)By similarity1
Metal bindingi45Iron-sulfur 1 (2Fe-2S)By similarity1
Metal bindingi48Iron-sulfur 1 (2Fe-2S)By similarity1
Metal bindingi67Iron-sulfur 1 (2Fe-2S)By similarity1
Metal bindingi99Iron-sulfur 2 (4Fe-4S); via tele nitrogenPROSITE-ProRule annotation1
Metal bindingi103Iron-sulfur 2 (4Fe-4S)PROSITE-ProRule annotation1
Metal bindingi106Iron-sulfur 2 (4Fe-4S)PROSITE-ProRule annotation1
Metal bindingi112Iron-sulfur 2 (4Fe-4S)PROSITE-ProRule annotation1
Metal bindingi151Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi154Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi157Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi201Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi228Iron-sulfur 4 (4Fe-4S)Sequence analysis1
Metal bindingi231Iron-sulfur 4 (4Fe-4S)Sequence analysis1
Metal bindingi235Iron-sulfur 4 (4Fe-4S)Sequence analysis1
Metal bindingi263Iron-sulfur 4 (4Fe-4S)Sequence analysis1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
Ligand2Fe-2S, 4Fe-4S, Iron, Iron-sulfur, Metal-binding, NAD

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		BAPH224915:G1G09-152-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit G (EC:7.1.1.-)
Alternative name(s):
NADH dehydrogenase I subunit G
NDH-1 subunit G
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nuoG
Ordered Locus Names:bbp_148
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224915 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Erwiniaceae › Buchnera ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000601 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001185441 – 907NADH-quinone oxidoreductase subunit GAdd BLAST907

Keywords - PTMi

Quinone

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		Q89AU1

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		224915.bbp_148

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 832Fe-2S ferredoxin-typePROSITE-ProRule annotationAdd BLAST83
Domaini83 – 1224Fe-4S His(Cys)3-ligated-typePROSITE-ProRule annotationAdd BLAST40
Domaini221 – 2774Fe-4S Mo/W bis-MGD-typePROSITE-ProRule annotationAdd BLAST57

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the complex I 75 kDa subunit family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1034, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000422_11_4_6

Identification of Orthologs from Complete Genome Data

More...OMAi		PSICHGC

Database of Orthologous Groups

More...OrthoDBi		323168at2

Family and domain databases

Conserved Domains Database

More...CDDi		cd00207, fer2, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036010, 2Fe-2S_ferredoxin-like_sf
IPR001041, 2Fe-2S_ferredoxin-type
IPR006656, Mopterin_OxRdtase
IPR006963, Mopterin_OxRdtase_4Fe-4S_dom
IPR000283, NADH_UbQ_OxRdtase_75kDa_su_CS
IPR010228, NADH_UbQ_OxRdtase_Gsu
IPR019574, NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04879, Molybdop_Fe4S4, 1 hit
PF00384, Molybdopterin, 1 hit
PF10588, NADH-G_4Fe-4S_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00926, Molybdop_Fe4S4, 1 hit
SM00929, NADH-G_4Fe-4S_3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54292, SSF54292, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01973, NuoG, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51085, 2FE2S_FER_2, 1 hit
PS51839, 4FE4S_HC3, 1 hit
PS51669, 4FE4S_MOW_BIS_MGD, 1 hit
PS00641, COMPLEX1_75K_1, 1 hit
PS00642, COMPLEX1_75K_2, 1 hit
PS00643, COMPLEX1_75K_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q89AU1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIIFVDNEE YNVDKSDNLL QACLSSGINI PYFCWHPVLG SIGSCRQCAV 
        60         70         80         90        100
TIYKDLEDKV GQLVMSCMTS VLDGMIVSTS DKISRNFRKG IIELLMLNHP 
       110        120        130        140        150
HDCPICEEGG SCHLQDMTVM AGHTVRRYRF TKRTHKNQYL GHFITHEMNR 
       160        170        180        190        200
CISCYRCVRY YKDYSGGTDL GVFGISNNVY FGRYNDGCLE SEFSGNLVEV 
       210        220        230        240        250
CPTGVFTDKT YSKKYSRKWD MQYAPSICQH CCVGCNISVG EKYGKISRIE 
       260        270        280        290        300
NRYHNAINHY FLCDLGRFSY DYSNVDERLT YSIYRSQNKT KIINDVNKTI 
       310        320        330        340        350
DKLAMKFKKS SKIIGIGSCR ASVESNFSLQ KLVGSENFYL GISQKEYDCL 
       360        370        380        390        400
MLIKDILKDN QIHVPTLREI EKSDVIFLLG EDVTKTSPLI ALSIRQSIKG 
       410        420        430        440        450
QVKTQDVSKN IPIWHADAVK NSFRNNKNKL FITNLMNSSL DDIADESYYA 
       460        470        480        490        500
STFDQVLLGA EVYKCISNNC ISNVTLLKQD LLSCAKRIAT ALTLSKCPLI 
       510        520        530        540        550
ISGSHSYNLD LIKVSFNIAK SLKVIGKNVG LILLSSNVNS IGVSLLEGIS 
       560        570        580        590        600
IEKVINKVLL KQIDKIIVLE NDLYRYLPES IVDTLFKSSS CTVVIDHLNT 
       610        620        630        640        650
RTLKQADIAI PTCNSFESSG TVVNYEGRAQ RFFKTYHPNS SENKKSILES 
       660        670        680        690        700
WKWLHLLYCK LHKISVFWHS LDDVIEEISL KIFSFSKLKD VAPNSSFKIF 
       710        720        730        740        750
GQKLARSHHR ASGRTALYSN INIHEPRPPQ DNDTMFSFSM EGCQNVQNYL 
       760        770        780        790        800
PYVPFSWFPG WNSVQSWNTY KKINNENYGK HLFQDTTKFV LTYYKLNCKN 
       810        820        830        840        850
VNKIEDLYLI VPCYFLFCNN ELAQYSPVIQ ENVLKNAYGI INTEDAKVLL 
       860        870        880        890        900
IESGSKIEFS YLNKNFSIKV QLSKEFKKGQ LGLPLGMADF PFFLAEKQVK 

VFRKISI
Length:907
Mass (Da):103,415
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i021643AD31F32E43
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE016826 Genomic DNA Translation: AAO26882.1

NCBI Reference Sequences

More...RefSeqi		WP_011091283.1, NC_004545.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAO26882; AAO26882; bbp_148

Database of genes from NCBI RefSeq genomes

More...GeneIDi		56470692

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		bab:bbp_148

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA Translation: AAO26882.1
RefSeqiWP_011091283.1, NC_004545.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi224915.bbp_148

Proteomic databases

PRIDEiQ89AU1

Genome annotation databases

EnsemblBacteriaiAAO26882; AAO26882; bbp_148
GeneIDi56470692
KEGGibab:bbp_148

Phylogenomic databases

eggNOGiCOG1034, Bacteria
HOGENOMiCLU_000422_11_4_6
OMAiPSICHGC
OrthoDBi323168at2

Enzyme and pathway databases

BioCyciBAPH224915:G1G09-152-MONOMER

Family and domain databases

CDDicd00207, fer2, 1 hit
InterProiView protein in InterPro
IPR036010, 2Fe-2S_ferredoxin-like_sf
IPR001041, 2Fe-2S_ferredoxin-type
IPR006656, Mopterin_OxRdtase
IPR006963, Mopterin_OxRdtase_4Fe-4S_dom
IPR000283, NADH_UbQ_OxRdtase_75kDa_su_CS
IPR010228, NADH_UbQ_OxRdtase_Gsu
IPR019574, NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd
PfamiView protein in Pfam
PF04879, Molybdop_Fe4S4, 1 hit
PF00384, Molybdopterin, 1 hit
PF10588, NADH-G_4Fe-4S_3, 1 hit
SMARTiView protein in SMART
SM00926, Molybdop_Fe4S4, 1 hit
SM00929, NADH-G_4Fe-4S_3, 1 hit
SUPFAMiSSF54292, SSF54292, 1 hit
TIGRFAMsiTIGR01973, NuoG, 1 hit
PROSITEiView protein in PROSITE
PS51085, 2FE2S_FER_2, 1 hit
PS51839, 4FE4S_HC3, 1 hit
PS51669, 4FE4S_MOW_BIS_MGD, 1 hit
PS00641, COMPLEX1_75K_1, 1 hit
PS00642, COMPLEX1_75K_2, 1 hit
PS00643, COMPLEX1_75K_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNUOG_BUCBP
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q89AU1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 14, 2003
Last sequence update: June 1, 2003
Last modified: April 7, 2021
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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