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Entry version 98 (07 Apr 2021)
Sequence version 1 (01 Jun 2003)
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Protein

Flagellar biosynthesis protein FlhA

Gene

flhA

Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BAPH224915:G1G09-227-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Flagellar biosynthesis protein FlhA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:flhA
Ordered Locus Names:bbp_223
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBuchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224915 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000601 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei21 – 43HelicalSequence analysisAdd BLAST23
Transmembranei47 – 64HelicalSequence analysisAdd BLAST18
Transmembranei76 – 98HelicalSequence analysisAdd BLAST23
Transmembranei118 – 140HelicalSequence analysisAdd BLAST23
Transmembranei209 – 231HelicalSequence analysisAdd BLAST23
Transmembranei251 – 273HelicalSequence analysisAdd BLAST23
Transmembranei285 – 307HelicalSequence analysisAdd BLAST23
Transmembranei311 – 333HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001900141 – 702Flagellar biosynthesis protein FlhAAdd BLAST702

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224915.bbp_223

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q89AN5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG1298, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015346_3_0_6

Identification of Orthologs from Complete Genome Data

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OMAi
MAINPGQ

Database of Orthologous Groups

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OrthoDBi
436367at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.490.80, 1 hit
1.10.8.540, 1 hit
3.40.30.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042194, FHIPEP_1
IPR042193, FHIPEP_3
IPR042196, FHIPEP_4
IPR025505, FHIPEP_CS
IPR006301, FlhA
IPR001712, T3SS_FHIPEP

The PANTHER Classification System

More...
PANTHERi
PTHR30161, PTHR30161, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00771, FHIPEP, 1 hit

PIRSF; a whole-protein classification database

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PIRSFi
PIRSF005419, FlhA, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00949, TYPE3IMAPROT

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01398, FlhA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00994, FHIPEP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q89AN5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANILSIFKT FEIKRLVKFQ TLSGPVLILI ILSMMVLPLA PFILDLFFTF
60 70 80 90 100
NIALSIVVLL MSMFTTKTLE FTSFPTILLF STLLRLALNI ASTRIILLNG
110 120 130 140 150
HIGSCSAGNV IQAFGHFLVG GNFTIGIIVF IILIIINFMV ITKGASRIAE
160 170 180 190 200
VGARFTLDGM PGKQMAIDAD LNAGLIGEKQ AKKRRIEINQ EADFYGSMDG
210 220 230 240 250
ASKFVRGDAI AGILIMIVNI IGGLVIGILQ HNMTFSQAAQ VYTILTIGDG
260 270 280 290 300
LVAQIPALVV STASGVIVTR VSTDQNVSEQ IVSQLFCNPQ VILLSGIVLG
310 320 330 340 350
VLGLVPGMPN IIFLIFTTLL FFISWLIYRN PVIFTNFEST MKKIDNTNFC
360 370 380 390 400
NISDASWNDV QLEGSISIEL GNLLIPMIKV NSKKSNLLDK IRNVRKKCAK
410 420 430 440 450
NIGFLPPLVH IRDNNNLPGN CYCILIKGIE ISKGTVQCGK FLAINSGNAS
460 470 480 490 500
GPLPLPAEET SDPIFKFKSF WITSELINQA KQKGYNIAED STVISTHLNH
510 520 530 540 550
IILTHISLLF GRQEAQQLLD YVSKFCPKLI EDLIPNSINL TIFHQVLQNL
560 570 580 590 600
LIENVPIRDM QTILETLITH APNYQNDSQI LTSLVRISLG KLIIQNIFQN
610 620 630 640 650
NKIEVIKFDS KLEQILLKTI ANKDSVLEPG LYNYIVVKLQ QEYNNCKLKN
660 670 680 690 700
IPCVLLVHHN LRVFIAKMLL KNIPKIFVLS NLELEDVTKI YTTNIIGDQT

KT
Length:702
Mass (Da):77,857
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8A0C091FCC9ED38
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE016826 Genomic DNA Translation: AAO26954.1

NCBI Reference Sequences

More...
RefSeqi
WP_011091355.1, NC_004545.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAO26954; AAO26954; bbp_223

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56470765

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bab:bbp_223

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016826 Genomic DNA Translation: AAO26954.1
RefSeqiWP_011091355.1, NC_004545.1

3D structure databases

SMRiQ89AN5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224915.bbp_223

Genome annotation databases

EnsemblBacteriaiAAO26954; AAO26954; bbp_223
GeneIDi56470765
KEGGibab:bbp_223

Phylogenomic databases

eggNOGiCOG1298, Bacteria
HOGENOMiCLU_015346_3_0_6
OMAiMAINPGQ
OrthoDBi436367at2

Enzyme and pathway databases

BioCyciBAPH224915:G1G09-227-MONOMER

Family and domain databases

Gene3Di1.10.490.80, 1 hit
1.10.8.540, 1 hit
3.40.30.60, 1 hit
InterProiView protein in InterPro
IPR042194, FHIPEP_1
IPR042193, FHIPEP_3
IPR042196, FHIPEP_4
IPR025505, FHIPEP_CS
IPR006301, FlhA
IPR001712, T3SS_FHIPEP
PANTHERiPTHR30161, PTHR30161, 1 hit
PfamiView protein in Pfam
PF00771, FHIPEP, 1 hit
PIRSFiPIRSF005419, FlhA, 1 hit
PRINTSiPR00949, TYPE3IMAPROT
TIGRFAMsiTIGR01398, FlhA, 1 hit
PROSITEiView protein in PROSITE
PS00994, FHIPEP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFLHA_BUCBP
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q89AN5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2003
Last modified: April 7, 2021
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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