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UniProtKB - Q88FY6 (NICT_PSEPK)
Protein
Putative metabolite transport protein NicT
Gene
nicT
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Status
Functioni
Probable transporter, possibly involved in the aerobic nicotinate degradation pathway.
1 PublicationGO - Molecular functioni
- transmembrane transporter activity Source: InterPro
GO - Biological processi
- aromatic compound catabolic process Source: UniProtKB-KW
Keywordsi
Biological process | Aromatic hydrocarbons catabolism, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Putative metabolite transport protein NicTAlternative name(s): Nicotinate degradation protein T |
Gene namesi | Name:nicT Ordered Locus Names:PP_3940 |
Organismi | Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) |
Taxonomic identifieri | 160488 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
Proteomesi |
|
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 28 – 48 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 66 – 86 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 93 – 113 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 123 – 143 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 152 – 172 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 189 – 209 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 254 – 274 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 290 – 310 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 320 – 340 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 347 – 367 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 374 – 394 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 411 – 431 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000418474 | 1 – 437 | Putative metabolite transport protein NicTAdd BLAST | 437 |
Expressioni
Inductioni
Repressed by NicR in the absence of 6-hydroxynicotinate (6HNA) inducer. In presence of 6HNA, repression is alleviated.1 Publication
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_0_0_6 |
OMAi | ERRWHII |
PhylomeDBi | Q88FY6 |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
Q88FY6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPIANATTVH SDIDHGTKAL YSKITWRLIP FLCFCYLAAY LDRINVGFAK
60 70 80 90 100
LQMLEDLQFS TAAYGLGAGL FFVGYIIFEV PSNLILQRVG AKLWIARIMI
110 120 130 140 150
TWGLLSACTM FVTSTTQFYI LRFLLGAAEA GFLPGVLYYL TMWYPTYRRG
160 170 180 190 200
RIIALFMIGL PLSSVIGGPI SGWIMGHFDQ VQGLHGWQWL FLLEAIPSVL
210 220 230 240 250
LGILTFWALP NHFQQAKWLS ADDKAQLAAD LAADDAEGKD SKHSFRDGFF
260 270 280 290 300
NLKVWMLGGI DFSILLSAYA MGFWMPTFIR DAGVSDTFHI GLLTAIPSLA
310 320 330 340 350
ALAGMLMIGA SSDRHRERRW HIIVPFIIGA IAMASSTLFS QNLVMTVVLF
360 370 380 390 400
AIASAAIIGA VPVFFSLPAT FLKGTAAATG FALACSVANI AGLVSNSLMG
410 420 430
VVTDLTGTSH AALWVFAGCL ILSCFLVIAL PAKLVNR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE015451 Genomic DNA Translation: AAN69534.1 |
RefSeqi | NP_746070.1, NC_002947.4 WP_003251108.1, NC_002947.4 |
Genome annotation databases
EnsemblBacteriai | AAN69534; AAN69534; PP_3940 |
KEGGi | ppu:PP_3940 |
PATRICi | fig|160488.4.peg.4194 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE015451 Genomic DNA Translation: AAN69534.1 |
RefSeqi | NP_746070.1, NC_002947.4 WP_003251108.1, NC_002947.4 |
3D structure databases
SMRi | Q88FY6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 160488.PP_3940 |
Genome annotation databases
EnsemblBacteriai | AAN69534; AAN69534; PP_3940 |
KEGGi | ppu:PP_3940 |
PATRICi | fig|160488.4.peg.4194 |
Phylogenomic databases
eggNOGi | COG2271, Bacteria |
HOGENOMi | CLU_001265_0_0_6 |
OMAi | ERRWHII |
PhylomeDBi | Q88FY6 |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NICT_PSEPK | |
Accessioni | Q88FY6Primary (citable) accession number: Q88FY6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 5, 2012 |
Last sequence update: | June 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families