Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 104 (11 Dec 2019)
Sequence version 1 (01 Jun 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Nicotinate dehydrogenase subunit B

Gene

nicB

Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of the two-component enzyme NicAB that mediates nicotinate hydroxylation, the first step in the aerobic nicotinate degradation pathway. Mediates conversion of nicotinate into 6-hydroxynicotinate (6HNA).2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mo-molybdopterin cytosine dinucleotideBy similarityNote: Binds 1 Mo-molybdopterin cytosine dinucleotide (Mo-MCD) cofactor per subunit.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: nicotinate degradation

This protein is involved in the pathway nicotinate degradation, which is part of Cofactor degradation.1 Publication
View all proteins of this organism that are known to be involved in the pathway nicotinate degradation and in Cofactor degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei818Heme 1 (covalent)PROSITE-ProRule annotation1
Binding sitei821Heme 1 (covalent)PROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi822Iron (heme 1 axial ligand)PROSITE-ProRule annotation1
Binding sitei964Heme 2 (covalent)PROSITE-ProRule annotation1
Binding sitei967Heme 2 (covalent)PROSITE-ProRule annotation1
Metal bindingi968Iron (heme 2 axial ligand)PROSITE-ProRule annotation1
Binding sitei1088Heme 3 (covalent)PROSITE-ProRule annotation1
Binding sitei1091Heme 3 (covalent)PROSITE-ProRule annotation1
Metal bindingi1092Iron (heme 3 axial ligand)PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Biological processAromatic hydrocarbons catabolism
LigandHeme, Iron, Metal-binding, Molybdenum

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:MONOMER-15546
PPUT160488:G1G01-4213-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
1.17.1.5 5092
1.17.2.1 5092

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA01010

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nicotinate dehydrogenase subunit B (EC:1.17.2.1)
Alternative name(s):
Nicotinate degradation protein B
Nicotinate dehydrogenase large subunit
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nicB
Synonyms:ndhL
Ordered Locus Names:PP_3948
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri160488 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000556 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei764 – 784HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells lacking both nicA and nicB lack the ability to hydroxylate nicotinate. Cells do not grow in a nicotinate medium but grow in a 6-hydroxynicotinate medium.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004184651 – 1187Nicotinate dehydrogenase subunit BAdd BLAST1187

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q88FX8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Repressed by NicS in the absence of 6-hydroxynicotinate (6HNA) or nicotinate inducers. In presence of 6HNA, repression is alleviated.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
160488.PP_3948

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q88FX8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini804 – 907Cytochrome c 1PROSITE-ProRule annotationAdd BLAST104
Domaini949 – 1057Cytochrome c 2PROSITE-ProRule annotationAdd BLAST109
Domaini1075 – 1163Cytochrome c 3PROSITE-ProRule annotationAdd BLAST89

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The cytochrome c domains probably enable interaction with the electron transfer chain, possibly by delivering the electrons to a cytochrome oxidase.1 Publication

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CE2 Bacteria
COG1529 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000166649

KEGG Orthology (KO)

More...
KOi
K18030

Identification of Orthologs from Complete Genome Data

More...
OMAi
WSAWVAD

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.760.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000674 Ald_Oxase/Xan_DH_a/b
IPR036856 Ald_Oxase/Xan_DH_a/b_sf
IPR008274 AldOxase/xan_DH_Mopterin-bd
IPR037165 AldOxase/xan_DH_Mopterin-bd_sf
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02738 Ald_Xan_dh_C2, 3 hits
PF00034 Cytochrom_C, 1 hit
PF13442 Cytochrome_CBB3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01008 Ald_Xan_dh_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46626 SSF46626, 3 hits
SSF54665 SSF54665, 1 hit
SSF56003 SSF56003, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51007 CYTC, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q88FX8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNHSQQVPSR DQLLAKTGVL LIVDQITPPS GPVAKGVTPT VKERELALFI
60 70 80 90 100
AVSDDGMVYA FNGHVDLGTG IRTSLAQIVA EELDLRMDQV HMVLGDTERA
110 120 130 140 150
PNQGATIASA TLQISAVPLR KAAATARRYL LQQAALRLGC PPEMLRIEDG
160 170 180 190 200
TVIASNGSTL SFAELVQGKN HQLHIADDAP LKAIEDYRLV GRSAPRVDIP
210 220 230 240 250
GKATGELTYV HDMRLPNMLH GRVIRPPYAG HDSGDFVGNS LLAVDESSIA
260 270 280 290 300
HLPGVVAVVV IRDFVGVVAE REEQAIRAAH ELKVSWKPFT GKLPDLSDVA
310 320 330 340 350
QAIRDNPRVQ RTVLDQGDVD GGIANASQRL SRSYLWPYQL HASIGPSCAL
360 370 380 390 400
ADFTAGQIRV WSGTQNPHLL RADLAWLLAC DEARIEIIRM EAAGCYGRNC
410 420 430 440 450
ADDVCADAVL LSRAVQRPVR VQLTREQEHV WEPKGTAQLM EIDGGLNADG
460 470 480 490 500
SVAAYDFQTS YPSNGAPTLA LLLTGAVEPV PALFEMGDRT SIPPYDYEHM
510 520 530 540 550
RVTINDMTPL VRASWMRGVS AMPNSFAHES YIDELAFAAG VDPVEYRLKH
560 570 580 590 600
LSDPRAIDLV KATAERAQWQ PHTRPMQTQA EGDVLRGRGF AYARYIHSKF
610 620 630 640 650
PGFGAAWAAW VADVAVDRRT GEVAVTRVVI GHDAGMMVNP EGVRHQIHGN
660 670 680 690 700
VIQSTSRVLK EQVSFEESTV ASKEWGGYPI LTFPELPAID VMMLPRQHEP
710 720 730 740 750
PMGSGESASV PSAAAIANAI FDATGIRFRE LPITAERVRA ALGGEGQGPD
760 770 780 790 800
APAPAQPSTK RSKWWFGSLA GVFGAALGML ATALPWRAEI APVTPPGVGS
810 820 830 840 850
WSAAMLERGR QVAAAGDCAV CHTVSGGKAN AGGLAMDTPF GTLYSTNITP
860 870 880 890 900
DPETGIGRWS FAAFERAMRE GISRDGRHLY PAFPYTSFRN INDADMQALY
910 920 930 940 950
AYLMSQTPVR QEAPANQMRF PFNQRPLMAG WNARFLQRGE YQPDPQRSAQ
960 970 980 990 1000
WNRGAYLVDG LGHCTACHSP RNLMGAEKGG SSYLAGGMVD GWEAPALNAL
1010 1020 1030 1040 1050
GKSSTPWSED ELFNYLSTGF SEKHGVAAGP MGPVVSELAT LPKSDVRAIA
1060 1070 1080 1090 1100
HYLSSLEGEP QALAANAAPQ VDTHVSLSNG ERVFKGACLG CHSDGLGPKL
1110 1120 1130 1140 1150
FGVSPSMAVN SNVHSDLPDN LLRVVLHGIP TPATRDLGYM PGFKDSLSDR
1160 1170 1180
QVADLAAYLR HRFAADKPAW QGLASKAAQV RANPGSH
Length:1,187
Mass (Da):127,875
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA237F711DB6CE4E5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU604833 Genomic DNA Translation: ACC64340.1
AE015451 Genomic DNA Translation: AAN69542.1

NCBI Reference Sequences

More...
RefSeqi
NP_746078.1, NC_002947.4
WP_010954765.1, NC_002947.4

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAN69542; AAN69542; PP_3948

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1046616

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ppu:PP_3948

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|160488.4.peg.4204

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU604833 Genomic DNA Translation: ACC64340.1
AE015451 Genomic DNA Translation: AAN69542.1
RefSeqiNP_746078.1, NC_002947.4
WP_010954765.1, NC_002947.4

3D structure databases

SMRiQ88FX8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi160488.PP_3948

Proteomic databases

PRIDEiQ88FX8

Genome annotation databases

EnsemblBacteriaiAAN69542; AAN69542; PP_3948
GeneIDi1046616
KEGGippu:PP_3948
PATRICifig|160488.4.peg.4204

Phylogenomic databases

eggNOGiENOG4105CE2 Bacteria
COG1529 LUCA
HOGENOMiHOG000166649
KOiK18030
OMAiWSAWVAD

Enzyme and pathway databases

UniPathwayiUPA01010
BioCyciMetaCyc:MONOMER-15546
PPUT160488:G1G01-4213-MONOMER
BRENDAi1.17.1.5 5092
1.17.2.1 5092

Family and domain databases

Gene3Di1.10.760.10, 3 hits
InterProiView protein in InterPro
IPR000674 Ald_Oxase/Xan_DH_a/b
IPR036856 Ald_Oxase/Xan_DH_a/b_sf
IPR008274 AldOxase/xan_DH_Mopterin-bd
IPR037165 AldOxase/xan_DH_Mopterin-bd_sf
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
PfamiView protein in Pfam
PF02738 Ald_Xan_dh_C2, 3 hits
PF00034 Cytochrom_C, 1 hit
PF13442 Cytochrome_CBB3, 1 hit
SMARTiView protein in SMART
SM01008 Ald_Xan_dh_C, 1 hit
SUPFAMiSSF46626 SSF46626, 3 hits
SSF54665 SSF54665, 1 hit
SSF56003 SSF56003, 2 hits
PROSITEiView protein in PROSITE
PS51007 CYTC, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNICB_PSEPK
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q88FX8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: June 1, 2003
Last modified: December 11, 2019
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again